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Original Articles Radiophysics/Radiobiology

Experimental investigation of the cell survival in dose cold spot

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Pages 16-24 | Received 08 Aug 2012, Accepted 10 Mar 2013, Published online: 25 Apr 2013

References

  • Wilt TJ, MacDonald R, Rutks I, Shamliyan TA, Taylor BC, Kane RL. Systematic review: Comparative effectiveness and harms of treatments for clinically localized prostate cancer. Ann Intern Med 2008;148:435–48.
  • Bromfield GP, Meng A, Warde P, Bristow RG. Cell death in irradiated prostate epithelial cells: Role of apoptotic and clonogenic cell kill. Prostate Cancer Prostatic Dis 2003;6: 73–85.
  • Tome WA, Fowler JF. On cold spots in tumor subvolumes. Med Phys 2002;29:1590–8.
  • Zhang Y, Zhou J, Baldwin J, Held KD, Prise KM, Redmond RW, et al. Ionizing radiation-induced bystander mutagenesis and adaptation: quantitative and temporal aspects. Mutat Res 2009;671:20–5.
  • Ryan LA, Seymour CB, Joiner MC, Mothersill CE. Radiation-induced adaptive response is not seen in cell lines showing a bystander effect but is seen in lines showing HRS/IRR response. Int J Radiat Biol 2009;85:87–95.
  • Hamada N. Evidence and significance of non-targeted effects of ionizing radiation. Curr Mol Pharmacol 2011;4:78.
  • Butterworth KT, McGarry CK, O’Sullivan JM, Hounsell AR, Prise KM. A study of the biological effects of modulated 6 MV radiation fields. Phys Med Biol 2010;55:1607–18.
  • Butterworth KT, McGarry CK, Trainor C, O’Sullivan JM, Hounsell AR, Prise KM. Out-of-field cell survival following exposure to intensity-modulated radiation fields. Int J Radiat Oncol Biol Phys 2011;79:1516–22.
  • Puck TT, Marcus PI. Action of x-rays on mammalian cells. J Exp Med 1956;103:653–66.
  • Mothersill C, Smith R, Singh H, Seymour C. Serum serotonin levels determine the magnitude and type of bystander effects in medium transfer experiments. Radiat Res 2010; 174:119–23.
  • Mothersill C, Seymour C. Medium from irradiated human epithelial cells but not human fibroblasts reduces the clonogenic survival of unirradiated cells. Int J Radiat Biol 1997; 71:421–7.
  • IAEA. Absorbed dose determination in external beam radiotherapy: An international code of practice based on the standards of absorbed dose to water. Technical Report Series 398. Vienna: IAEA; 2000.
  • Klipp E, Liebermeister W. Mathematical modeling of intracellular signaling pathways. BMC Neurosci 2006;7 (Suppl 1):S10.
  • Nagar S, Smith LE, Morgan WF. Mechanisms of cell death associated with death-inducing factors from genomically unstable cell lines. Mutagenesis 2003;18:549–60.
  • Schaue D, Kachikwu E, McBride W. Cytokines in radiobiological responses: A review. Radiat Res 2012;178:505–23.
  • Muller K, Meineke V. Radiation-induced alterations in cytokine production by skin cells. Exp Hematol 2007;35(4 Suppl 1):96–104.
  • Bentzen SM. Preventing or reducing late side effects of radiation therapy: Radiobiology meets molecular pathology. Nat Rev Cancer 2006;6:702–13.
  • Burr KL, Robinson JI, Rastogi S, Boylan MT, Coates PJ, Lorimore SA, et al. Radiation-induced delayed bystander-type effects mediated by hemopoietic cells. Radiat Res 2010;173:760–8.
  • Hei TK, Zhou H, Ivanov VN, Hong M, Lieberman HB, Brenner DJ, et al. Mechanism of radiation-induced bystander effects: A unifying model. J Pharm Pharmacol 2008;60: 943–50.
  • Hei TK, Zhou H, Chai Y, Ponnaiya B, Ivanov VN. Radiation induced non-targeted response: Mechanism and potential clinical implications. Curr Mol Pharmacol 2011;4:96–105.
  • Zhou H, Ivanov VN, Gillespie J, Geard CR, Amundson SA, Brenner DJ, et al. Mechanism of radiation-induced bystander effect: Role of the cyclooxygenase-2 signaling pathway. Proc Natl Acad Sci U S A 2005;102:14641–6.
  • Mackonis EC, Suchowerska N, Zhang M, Ebert M, McKenzie DR, Jackson M. Cellular response to modulated radiation fields. Phys Med Biol 2007; 52:5469–82.
  • Mariotti L, Facoetti A, Alloni D, Bertolotti A, Ranza E, Ottolenghi A. Effects of ionizing radiation on cell-to-cell communication. Radiat Res 2010;174:280–9.
  • Bromley R, Davey R, Oliver L, Harvie R, Baldock C. A preliminary investigation of cell growth after irradiation using a modulated x-ray intensity pattern. Phys Med Biol 2006;51: 3639–51.
  • Bromley R, Oliver L, Davey R, Harvie R, Baldock C. Predicting the clonogenic survival of A549 cells after modulated x-ray irradiation using the linear quadratic model. Phys Med Biol 2009;54:187–206.
  • Butterworth KT, McGarry CK, O’Sullivan JM, Hounsell AR, Prise KM. A study of the biological effects of modulated 6 MV radiation fields. Phys Med Biol 2010;55:1607–18.
  • Trainor C, Butterworth K, Mc Garry C. DNA damage responses following exposure to modulated radiation fields. PLoS One 2012;7:e43326.
  • Suchowerska N, Ebert MA, Zhang M, Jackson M. In vitro response of tumour cells to non-uniform irradiation. Phys Med Biol 2005;50:3041–51.
  • Lisbona A, Averbeck D, Supiot S, Delpon G, Ali D, Vinas F, et al. IMRT combined to IGRT: increase of the irradiated volume. Consequences? Cancer Radiother 2010;14:563–70.

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