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Original Article

Cochlear damage in guinea pigs following contralateral sound stimulation with and without gentamicin

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Pages 183-193 | Received 28 Aug 1992, Accepted 06 May 1993, Published online: 12 Oct 2009

References

  • Black J., Calesnick B., Williams D., Weinstein M. J. Pharmacology of gentamicin: a new broad-spectrum antibiotic. Antimicrob Agents Chemother 1963; 138: 47
  • Cody A. R., Johnstone B. M. Acoustic trauma: single neuron basis for the half-octave shift. J Acoust Soc Am 1981; 70: 707–11
  • Cody A. R., Johnstone B. M. Temporary threshold shift modified by binaural acoustic stimulation. Hear Res 1982; 6: 199–205
  • Cody A. R., Robertson D. Variability of noisc-induccd damage in the guinea pig cochlea: electrophysiological and morphological correlates after strictly controlled exposures. Hear Res 1983; 9: 55–70
  • Coleman J. W. Age dependent changes and acoustic trauma in the spiral organ of the guinea pig. Scand Audiol 1976; 5: 63–8
  • Collins P. W. P., Twine J. M. The ototoxic effects of different doses of gentamicin on the cochlea of pigmented guinea pigs. Br J Audiol 1985; 19: 257–64
  • Collins P. W. P. Synergistic interactions of gentamicin and pure tones causing cochlear hair cell loss in pigmented guinea pigs. Hear Res 1988a; 36: 249–60
  • Collins P. W. P. Synergistic interactions of gentamicin and noise: hair cell loss and BSER audiometry. Br J Audiol 1988b; 22: 133, (Abstract)
  • Collins P. W. P. Damaging effects of gentamicin and sound on cochlear structure and function in guinea pigs. Doctoral Thesis. University of London. 1989
  • Dodson H. C., Walliker J. R., Frampton S., Douek E. E., Fourcin A. J., Bannister L. H. Structural alteration of hair cells in the contralateral ear resulting from extracochlear electrical stimulation. Nature 1986; 320: 65–7
  • Engstrom H., Ades H. W., Anderson A. Structural Pattern of the Organ of Corti. Almquist and Wiksell, Stockholm 1966
  • Engstrom H., Engstrom B. Structural changes in the cochlea following overstimulation by noise. Acta Oto-laryngol (Stockh) 1979; 75–9, (Suppl. 360)
  • Forge A. Outer hair cell loss and supporting cell expansion following chronic gentamicin treatment. Hear Res 1985; 19: 171–82
  • Forge A., Wright A., Davies S. J. Analysis of structural changes in the stria vascularis following chronic gentamicin treatment. Hear Res 1987; 31: 253–66
  • Hawkins J. E., Johnsson L. G. Micro-dissection and surface preparation of the inner ear. Handbook of Auditory and Vestibular Methods, C. A. Smith, J. A. Vernon. Thomas, Springfield, IL 1975; 5–52
  • Hawkins J. E. Drug ototoxicily. Handbook of Sensory Physiology, Vol. V/3, W. D. Kiedel, W. D. Neff. Springer-Verlag, New York 1976; 707–48
  • Hawkins J. E., Johnsson L. G. Histopathology of cochlear and vestibular ototoxicity in laboratory animals. Aminoglycoside Ototoxicity, S. A. Lerner, G. J. Matz, J. E. Hawkins. Little, Brown, Boston, MA 1981; 175–95
  • Hildesheimer M., Makai E., Muchnik C., Rubenstein M. The influence of the efferent system on acoustic overstimulation. Hear Res 1990; 43: 263–8
  • Huntcr-Duvar I. H., Suzuki M., Mount R. J. Anatomical changes in the organ of Corti after acoustic stimulation. New Perspectives in Noise Induced Hearing Loss, R. P. Hamernik, D. Henderson, R. Salvi. Raven Press, New York 1982; 3–22
  • Jackson G. G., Arcieri G. Ototoxicity of gentamicin in man: a survey and controlled analysis of clinical experience in the United States. J Infect Dis 1971; 124: 130–7, (Suppl.)
  • McDowell B. Ototoxicity of gentamicin in guinea pigs: a light microscopical study. Doctoral Thesis. University of London. 1983
  • McDowell B. The ototoxicity of repetitive chronic aminoglycoside administration. Acta Otolaryngol (Stockh) 1986; 101: 242–6
  • McDowell B., Davies S., Forge A. The effect of gentamicin-induced hair cell loss on the tight junctions of the recticular lamina. Hear Res 1989; 40: 221–32
  • Pye A. Structural cochlear changes after noise exposure. Proc Inst Acoust 1987; 9: 289–98
  • Pye A., Ulehlova L. A comparison of initial and permanent surface changes to guinea pig hair cells after acoustic overstimulation. Arch Otorhinolaryngol 1989; 246: 3–10
  • Rajan R., Johnstone B. M. Crossed cochlear influences on monaural temporary threshold shifts. Hear Res 1983; 9: 279–94
  • Rajan R., Johnstone B. M. Binaural acoustic stimulation exercises protective effects on the cochlea that mimic the effects of electrical stimulation of an auditory efferent pathway. Brain Res 1988; 459: 241–55
  • Rajan R., Johnstone B. M. Contralateral cochlear destruction mediates protection from monaural loud sound exposures through the crossed olivocochlear bundle. Hear Res 1989; 39: 263–78
  • Rajan R. The effects of upper pontine transections on normal cochlear responses and on the protective effects of contralateral acoustic stimulation in barbiturate-anaesthetised normal-hearing guinea pigs. Hear Res 1990a; 45: 137–44
  • Rajan R. Electrical stimulation of the inferior colliculus at low rates protects the cochlea from auditory desen-sitization. Brain Res 1990b; 506: 192–204
  • Robertson D., Johnstone B. M. Acoustic trauma in the guinea pig cochlea: early changes in ultrastructure and neural threshold. Hear Res 1980; 3: 167–79
  • Saunders J. C. Dear, S. C., Schneider M. E. The anatomical consequences of acoustic injury: a review and tutorial. J Acoust Soc Am 1985; 78: 833–60
  • Schacht J. Molecular mechanisms of drug induced hearing loss. Hear Res 1986; 22: 297–304
  • Slepecky N. Overview of mechanical damage to the inner car: noise as a tool to probe cochlear function. Hear Res 1986; 22: 307–21
  • Spoendlin H., Brun J. P. Relation of structural damage to exposure time and intensity in acoustic trauma. Acta Otolaryngol (Stockh) 1973; 75: 220–6
  • Tange R. A., Conijn E. A. J. G., Van Zeijl L. G. P. M., Huizing E. H. Pattern of gentamicin-induced degeneration in the guinea pig. A morphological and elcctrophysiological study. Arch Otorhinolaryngol 1982; 236: 173–84
  • Ulehlova L. Normal cellular pattern of the organ of Corti in the guinea pig. Arch Otorhinolaryngol 1973; 204: 321–30
  • Warren E. H., Liberman M. C. Effects of contralaleral sound on auditory-nerve responses. Hear Res 1989; 37: 105–22
  • Wersall J. Structural damage to the organ of Corti and the vestibular epithelia caused by aminoglycoside antibiotics in the guinea pig. Aminoglycoside Ototoxicity, S. A. Lerner, G. J. Matz, J. E. Hawkins. Little, Brown, Boston, MA 1981; 389–408
  • Ylikoski J., Wersall J., Bjorkroth B. Hearing loss and cochlear pathology in gentamicin intoxicated guinea pigs. Acta Path Microbiol Scand 1973; 81: 30–47, (Suppl. 241)

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