Curcumin improves tendon healing in rats: a histological, biochemical, and functional evaluation

References

• Postacchini F, Puddu G. Subcutaneous ruptures of the Achilles tendon. Int Surg 1976;4:145–50.
   Google Scholar
• Chai W, Ni M, Rui YF, Zhang KY, Zhang Q, Xu LL, Chan KM, Li G, Wang Y. Effect of growth and differentiation factor 6 on the tenogenic differentiation of bone marrow-derived mesenchymal stem cells. Chin Med J 2013;126(8):1509–16.
   PubMed Web of Science ®Google Scholar
• Kaux JF, Janssen L, Drion P, Nusgens B, Libertiaux V, Pascon F, Heyeres A, Hoffmann A, Lambert C, Le Goff C, Denoël V, Defraigne JO, Rickert M, Crielaard JM, Colige A. Vascular Endothelial Growth Factor-111 (VEGF-111) and tendon healing: preliminary results in a rat model of tendon injury. Muscle Ligaments Tendons J. 2014;4(1):24–8.
   PubMedGoogle Scholar
• Yin Z, Chen X, Zhu T, Hu JJ, Song HX, Shen WL, Jiang LY, Heng BC, Ji JF, Ouyang HW. The effect of decellularized matrices on human tendon stem/progenitor cells differentiation and tendon repair. Acta Biomater 2013;9(12):9317–29.
   PubMed Web of Science ®Google Scholar
• Jiang D, Xu B, Yang M, Zhao Z, Zhang Y, Li Z. Efficacy of tendon stem cells in fibroblast-derived matrix for tendon tissue engineering. Cytotherapy 2014;16(5):662–73.
   PubMed Web of Science ®Google Scholar
• Ni M, Rui YF, Tan Q, Liu Y, Xu LL, Chan KM, Wang Y, Li G. Engineered scaffold-free tendon tissue produced by tendon-derived stem cells. Biomaterials 2013;34(8):2024–37.
   PubMed Web of Science ®Google Scholar
• Tamaddonfard E, Farshid AA, Ahmadian E, Hamidhoseyni A. Crocin enhanced functional recovery after sciatic nerve crush injury in rats. Iran J Basic Med Sci 2013; 16(1):83–90.
   PubMed Web of Science ®Google Scholar
• Sheng QS, Wang ZJ, Zhang J, Zhang YG. Salidroside promotes peripheral nerve regeneration following crush injury to the sciatic nerve in rats. Neuroreport 2013;24(5):217–23.
   PubMed Web of Science ®Google Scholar
• Aiyegbusi AI, Duru FI, Anunobi CC, Noronha CC, Okanlawon AO. Bromelain in the early phase of healing in acute crush Achilles tendon injury. Phytother Res PTR 2011;25(1):49–52.
   PubMed Web of Science ®Google Scholar
• Kulac M, Aktas C, Tulubas F, Uygur R, Kanter M, Erboga M, Ceber M, Topcu B, Ozen OA. The effects of topical treatment with curcumin on burn wound healing in rats. J Mol Histol 2013;44(1):83–90.
   PubMed Web of Science ®Google Scholar
• Ma J, Liu J, Yu H, Wang Q, Chen Y, Xiang L. Curcumin promotes nerve regeneration and functional recovery in rat model of nerve crush injury. Neurosci Lett 2013;547:26–31.
   PubMed Web of Science ®Google Scholar
• Castangia I, Nácher A, Caddeo C, Valenti D, Fadda AM, Díez-Sales O, Ruiz-Saurí A, Manconi M. Fabrication of quercetin and curcumin bionanovesicles for the prevention and rapid regeneration of full-thickness skin defects on mice. Acta Biomater 2014;10(3):1292–300.
   PubMed Web of Science ®Google Scholar
• Strimpakos AS, Sharma RA. Curcumin: preventive and therapeutic properties in laboratory studies and clinical trials. Antioxidants Redox Signal 2008;10(3):511–45.
   PubMed Web of Science ®Google Scholar
• Li X, Chen S, Zhang B, Li M, Diao K, Zhang Z, Li J, Xu Y, Wang X, Chen H. In situ injectable nano-composite hydrogel composed of curcumin, N,O-carboxymethyl chitosan and oxidized alginate for wound healing application. Int J Pharmaceut 2012;437(1–2):110–9.
   PubMed Web of Science ®Google Scholar
• Yu L, Yi J, Ye G, Zheng Y, Song Z, Yang Y, Song Y, Wang Z, Bao Q. Effects of curcumin on levels of nitric oxide synthase and AQP-4 in a rat model of hypoxia-ischemic brain damage. Brain Res 2012, 1475:88–95.
   PubMed Web of Science ®Google Scholar
• Buhrmann C, Mobasheri A, Busch F, Aldinger C, Stahlmann R, Montaseri A, Shakibaei M. Curcumin modulates nuclear factor kappaB (NF-kappaB)-mediated inflammation in human tenocytes in vitro: role of the phosphatidylinositol 3-kinase/Akt pathway. J Biol Chem 2011;286(32):28556–66.
   PubMed Web of Science ®Google Scholar
• Alaseirlis DA, Li Y, Cilli F, Fu FH, Wang JH. Decreasing inflammatory response of injured patellar tendons results in increased collagen fibril diameters. Connective Tissue Res 2005;46(1):12–7.
   PubMed Web of Science ®Google Scholar
• Park HB, Hah YS, Yang JW, Nam JB, Cho SH, Jeong ST. Antiapoptotic effects of anthocyanins on rotator cuff tenofibroblasts. J Orthopaedic Res Off Publ Orthopaedic Res Soc 2010;28:1162–9.
   PubMed Web of Science ®Google Scholar
• Ni M, Lui PP, Rui YF, Lee YW, Lee YW, Tan Q, Wong YM, Kong SK, Lau PM, Li G, Chan KM. Tendon-derived stem cells (TDSCs) promote tendon repair in a rat patellar tendon window defect model. J Orthopaedic Res Off Publ Orthopaedic Res Soc 2012;30(4):613–9.
   PubMed Web of Science ®Google Scholar
• Jagetia GC, Rajanikant GK. Acceleration of wound repair by curcumin in the excision wound of mice exposed to different doses of fractionated gamma radiation. Int Wound J 2012;9(1):76–92.
   PubMed Web of Science ®Google Scholar
• Guerra Fda R1, Vieira CP, Almeida MS, Oliveira LP, de Aro AA, Pimentel ER. LLLT improves tendon healing through increase of MMP activity and collagen synthesis. Lasers Med Sci 2013;28(5):1281–8.
   Google Scholar
• Panchatcharam M, Miriyala S, Gayathri VS, Suguna L. Curcumin improves wound healing by modulating collagen and decreasing reactive oxygen species. Mol Cell Biochem 2006;290(1–2):87–96.
   PubMed Web of Science ®Google Scholar
• Sharma AV, Ganguly K, Paul S, Maulik N, Swarnakar S. Curcumin heals indomethacin-induced gastric ulceration by stimulation of angiogenesis and restitution of collagen fibers via VEGF and MMP-2 mediated signaling. Antioxidants Redox Signal 2012;16(4):351–62.
   PubMed Web of Science ®Google Scholar
• Lopez-Jornet P, Camacho-Alonso F, Jimenez-Torres MJ, Orduna-Domingo A, Gomez-Garcia F. Topical curcumin for the healing of carbon dioxide laser skin wounds in mice. Photomed Laser Surg 2011;29(12):809–14.
   PubMed Web of Science ®Google Scholar
• Rattan SI, Fernandes RA, Demirovic D, Dymek B, Lima CF. Heat stress and hormetin-induced hormesis in human cells: effects on aging, wound healing, angiogenesis, and differentiation. Dose-Response Publ Int Hormesis Soc 2009;7(1):90–103.
   PubMed Web of Science ®Google Scholar
• Scharstuhl A, Mutsaers HA, Pennings SW, Szarek WA, Russel FG, Wagener FA. Curcumin-induced fibroblast apoptosis and in vitro wound contraction are regulated by antioxidants and heme oxygenase: implications for scar formation. J Cell Mol Med 2009;13(4):712–25.
   PubMed Web of Science ®Google Scholar
• Clore JN, Cohen IK, Diegelmann RF. Quantitation of collagen types I and III during wound healing in rat skin. Proc Soc Exp Biol Med 1979;161(3):337–40.
   PubMed Web of Science ®Google Scholar
• Eriksen HA1, Pajala A, Leppilahti J, Risteli J. Increased content of type III collagen at the rupture site of human Achilles tendon. J Orthopaedic Res Off Publ Orthopaedic Res Soc 2002;20(6):1352–7.
   PubMed Web of Science ®Google Scholar
• Kant V, Gopal A, Pathak NN, Kumar P, Tandan SK, Kumar D. Antioxidant and anti-inflammatory potential of curcumin accelerated the cutaneous wound healing in streptozotocin-induced diabetic rats. Int Immunopharmacol 2014;20(2):322–30.
   PubMed Web of Science ®Google Scholar
• Shukunami C1, Takimoto A, Oro M, Hiraki Y. Scleraxis positively regulates the expression of tenomodulin, a differentiation marker of tenocytes. Dev Biol 2006;298(1):234–47.
   Google Scholar
• Poulsen RC, Knowles HJ, Carr AJ, Hulley PA. Cell differentiation versus cell death: extracellular glucose is a key determinant of cell fate following oxidative stress exposure. Cell Death Dis 2014;5:e1074.
   PubMed Web of Science ®Google Scholar
• Kitamura N, Tohyama H, Nishihira J, Hatano M, Suzuki M, Yasuda K. Stress deprivation enhances manganese superoxide dismutase expression in the rat patellar tendon. Int J Mol Med 2004;14(4):537–43.
   PubMed Web of Science ®Google Scholar