References
- Reveille JD, Sims AM, Danoy P, Evans DM, Leo P, Pointon JJ, et al. Genome-wide association study of ankylosing spondylitis identifies non-MHC susceptibility loci. Nat Genet 2010;42:123–7.
- Lea WI, Lee YH. The associations between interleukin-1 polymorphisms and susceptibility to ankylosing spondylitis: a meta-analysis. Joint Bone Spine 2012;79:370–4.
- Strowig T, Henao-Mejia J, Elinav E, Flavell R. Inflammasomes in health and disease. Nature 2012;481:278–86.
- Villani AC, Lemire M, Fortin G, Louis E, Silverberg MS, Collette C, et al. Common variants in the NLRP3 region contribute to Crohn’s disease susceptibility. Nat Genet 2009;41:71–6.
- Verma D, Sarndahl E, Andersson H, Eriksson P, Fredrikson M, Jonsson JI, et al. The Q705K polymorphism in NLRP3 is a gain-of-function alteration leading to excessive interleukin-1beta and IL-18 production. PLoS One 2012;7:e34977.
- Schoultz I, Verma D, Halfvarsson J, Torkvist L, Fredrikson M, Sjoqvist U, et al. Combined polymorphisms in genes encoding the inflammasome components NALP3 and CARD8 confer susceptibility to Crohn’s disease in Swedish men. Am J Gastroenterol 2009;104:1180–8.
- Roberts RL, Topless RKG, Phipps-Green AJ, Gearry RB, Barclay ML, Merriman TR. Evidence of interaction of CARD8 rs2043211 with NALP3 rs35829419 in Crohn’s disease. Genes Immun 2010;11:351–6.
- Fontalba A, Martinez-Taboada V, Gutierrez O, Pipaon C, Benito N, Balsa A, et al. Deficiency of the NF-kappaB inhibitor caspase activating and recruitment domain 8 in patients with rheumatoid arthritis is associated with disease severity. J Immunol 2007;179:4867–73.
- McGovern DP, Butler H, Ahmad T, Paolucci M, van Heel DA, Negoro K, et al. TUCAN (CARD8) genetic variants and inflammatory bowel disease. Gastroenterology 2006;131:1190–6.
- Fisher SA, Mirza MM, Onnie CM, Soars D, Lewis CM, Prescott NJ, et al. Combined evidence from three large British Association studies rejects TUCAN/CARD8 as an IBD susceptibility gene. Gastroenterology 2007;132:2078–80.
- Büning C, Schmidt HHJ, Molnár T, Drenth JPH, Fiedler T, Gentz E, et al. No association of the CARD8 (TUCAN) c.30T>A (p.C10X) variant with Crohn’s disease: a study in 3 independent European cohorts. Inflamm Bowel Dis 2008;14:332–7.
- Kastbom A, Verma D, Eriksson P, Skogh T, Wingren G, Söderkvist P. Genetic variation in proteins of the cryopyrin inflammasome influences susceptibility and severity of rheumatoid arthritis (the Swedish TIRA project). Rheumatology 2008;47:415–17.
- Kastbom A, Johansson M, Verma D, Söderkvist P, Rantapää-Dahlqvist S. CARD8 p.C10X polymorphism is associated with inflammatory activity in early rheumatoid arthritis. Ann Rheum Dis 2010;69:723–6.
- Klingberg E, Carlsten H, Hilme E, Hedberg M, Forsblad-d’Elia H. Calprotectin in ankylosing spondylitis – frequently elevated in feces, but normal in serum. Scand J Gastroenterol 2012;47:435–44.
- Pointon JJ, Timms AE, Bradbury L, Brown MA, Wordsworth P. Analysis of positional candidate genes in ankylosing spondylitis: a possible role for ENPP1. Rheumatology 2006;45:I60.