References
- Bergstrom A, Pisani P, Tenet V, Wolk A, Adami HO. 2001. Overweight as an avoidable cause of cancer in Europe. Int J Cancer 91:421–430
- Borecki IB, Higgins M, Schreiner PJ, Arnett DK, Mayer-Davis E, Hunt SC, Province MA. 1998. Evidence for multiple determinants of the body mass index: the National Heart, Lung, and Blood Institute Family Heart Study. Obes Res 6:107–114
- Chawla A, Boisvert WA, Lee CH, Laffitte BA, Barak Y, Joseph SB, Liao D, et al. 2001. A PPAR gamma-LXR-ABCA1 pathway in macrophages is involved in cholesterol efflux and atherogenesis. Mol Cell 7:161–171
- Cheung WW, Mao P. 2012. Recent advances in obesity: genetics and beyond. ISRN Endocrinol 2012;536905
- Dahlman I, Nilsson M, Jiao H, Hoffstedt J, Lindgren CM, Humphreys K, Kere J, et al. 2006. Liver X receptor gene polymorphisms and adipose tissue expression levels in obesity. Pharmacogenet Genomics 16:881–889
- Europe WHOROF. 1989. Measuring Obesity -- Classification and description of anthropometric data: report on a WHO consultation on the epidemiology of obesity. Warsaw: National Food and Nutrition Institute
- Gaunt TR, Rodriguez S, Day INM. 2007. Cubic exact solutions for the estimation of pairwise haplotype frequencies: implications for linkage disequilibrium analyses and a web tool “CubeX”. BMC Bioinformatics 8:428. doi: 10.1186/1471-2105-8-428
- James PT. 2004. Obesity: the worldwide epidemic. Clin Dermatol 22:276–280
- Juvet LK, Andresen SM, Schuster GU, Dalen KT, Tobin KAR, Hollung K, Haugen F, et al. 2003. On the role of liver X receptors in lipid accumulation in adipocytes. Mol Endocrinol 17:172–182
- Kohro T, Nakajima T, Wada Y, Sugiyama A, Ishii M, Tsutsumi S, Aburatani H, et al. 2000. Genomic structure and mapping of human orphan receptor LXR alpha: upregulation of LXRa mRNA during monocyte to macrophage differentiation. J Atheroscler Thromb 7:145–151
- Kopelman PG. 2000. Obesity as a medical problem. Nature 404:635–643
- Kozak M. 1987. At least six nucleotides preceding the AUG initiator codon enhance translation in mammalian cells. J Mol Biol 196:947–950
- Laffitte BA, Chao LC, Li J, Walczak R, Hummasti S, Joseph SB, Castrillo A, et al. 2003. Activation of liver X receptor improves glucose tolerance through coordinate regulation of glucose metabolism in liver and adipose tissue. Proc Natl Acad Sci USA 100:5419–5424
- Legry V, Cottel D, Ferrieres J, Chinetti G, Deroide T, Staels B, Amouyel P, Meirhaeghe A. 2008. Association between liver X receptor alpha gene polymorphisms and risk of metabolic syndrome in French populations. Int J Obes (Lond) 32:421–428
- Loos RJF. 2012. Genetic determinants of common obesity and their value in prediction. Best Pract Res Clin Endocrinol Metab 26:211–226
- Luan J, Browne PO, Harding AH, Halsall DJ, O'rahilly S, Chatterjee VK, Wareham NJ. 2001. Evidence for gene--nutrient interaction at the PPARgamma locus. Diabetes 50:686–689
- Lund EG, Peterson LB, Adams AD, Lam MH, Burton CA, Chin J, Guo Q, et al. 2006. Different roles of liver X receptor alpha and beta in lipid metabolism: effects of an alpha-selective and a dual agonist in mice deficient in each subtype. Biochem Pharmacol 71:453–463
- Ogden CL, Yanovski SZ, Carroll MD, Flegal KM. 2007. The epidemiology of obesity. Gastroenterology 132:2087--2102
- Price ET, Pacanowski MA, Martin MA, Cooper-Dehoff RM, Pepine CJ, Zineh I, Johnson JA. 2011. Liver X receptor alpha gene polymorphisms and variable cardiovascular outcomes in patients treated with antihypertensive therapy: results from the INVEST-GENES study. Pharmacogenet Genomics 21:333–340
- Rankinen T, Zuberi A, Chagnon YC, Weisnagel SJ, Argyropoulos G, Walts B, Perusse L, Bouchard C. 2006. The human obesity gene map: The 2005 update. Obesity 14:529–644
- Robitaille J, Houde A, Lemieux S, Gaudet D, Perusse L, Vohl MC. 2007. The lipoprotein/lipid profile is modulated by a gene--diet interaction effect between polymorphisms in the liver X receptor-alpha and dietary cholesterol intake in French-Canadians. Br J Nutr 97:11–18
- Sabatti C, Service SK, Hartikainen AL, Pouta A, Ripatti S, Brodsky J, Jones CG, et al. 2009. Genome-wide association analysis of metabolic traits in a birth cohort from a founder population. Nat Genet 41:35–46
- Tobin KAR, Steineger HH, Alberti S, Spydevold O, Auwerx J, Gustafsson JA, Nebb HI. 2000. Cross-talk between fatty acid and cholesterol metabolism mediated by liver X receptor-alpha. Mol Endocrinol 14:741–752