194
Views
19
CrossRef citations to date
0
Altmetric
Research Paper

The association between endothelial nitric oxide synthase gene G894T polymorphism and hypertension in Han Chinese: a case-control study and an updated meta-analysis

, , , , , , , & show all
Pages 185-195 | Received 14 Jan 2014, Accepted 27 Mar 2014, Published online: 21 May 2014

References

  • Cavalli-Sforza LL. 1998. The Chinese human genome diversity project. Proc Natl Acad Sci USA 95:11501–11503
  • Chao YX. 2006. Association of endothelial nitric oxide synthase gene polymorphism with essential hypertension and its cardiocerebrovascular complications. (Unpublished)
  • Chen LN, Xu QB, Ma P. 2011. Relationship between G894T polymorphism of endothelial nitric oxide synthesis gene and essential hypertension in Han ethnicity of Ningxia. Ningxia Yi Ke Da Xue Xue Bao 33:909–911
  • Chu JY, Huang W, Kuang SQ, Wang JM, Xu JJ. 1998. Genetic relationship of populations in China. Proc Natl Acad Sci USA 95:11763–11768
  • Dang HS, Chen W. 2006. Genic polymorphism of plasma endothelial nitric oxide synthase in patients with coronary heart disease induced by essential hypertension in relation to the gender, age and family history. Zhongguo Lin Chuang Kang Fu Za Zhi 10:4–12
  • Di Q, Zhan YY, Chen YL, Ding XJ. 2002. Association of Glu298Asp polymorphism of the endothelial nitric oxide synthase gene with essential hypertension in old people. Zhongguo Quan Ke Yi Xue Za Zhi 5:355–357
  • Dong HY, Li JQ, Wang Q, Luo ZG. 2006. Association between essential hypertension and the polymorphism of angiotensin-conversion enzyme gene and endothelial nitric oxide synthase gene. Zhongguo Yi Shi Za Zhi 8:1059–1061
  • Egger M, Davey Smith G, Schneider M, Minder C. 1997. Bias in meta-analysis detected by a simple, graphical test. BMJ 315:629–634
  • Fairchild TA, Fulton D, Fontana JT, Gratton JP, McCabe TJ, Sessa WC. 2001. Acidic hydrolysis as a mechanism for the cleavage of the Glu(298)Asp variant of human endothelial nitric-oxide synthase. J Biol Chem 276:26674–26679
  • Greene CS, Penrod NM, Williams SM, Moore JH. 2009. Failure to replicate a genetic association may provide important clues about genetic architecture. PLoS One 4:e5639
  • Gu D, Su S, Ge D, Chen S, Huang J, Li B, Chen R, Qiang B. 2006. Association study with 33 single-nucleotide polymorphisms in 11 candidate genes for hypertension in Chinese. Hypertension 47:1147–1154
  • Higgins JP, Thompson SG, Deeks JJ, Altman PG. 2003. Measuring inconsistency in meta-analysis. BMJ 327:557–560
  • Hingorani AD. 2001. Polymorphisms in endothelial nitric oxide synthase and atherogenesis: John French Lecture 2000. Atherosclerosis 154:521–527
  • Hingorani AD, Liang CF, Fatibene J, Lyon A, Monteith S, Parsons A, Haydock S, et al. 1999. A common variant of the endothelial nitric oxide synthase (Glu298->Asp) is a major risk factor for coronary artery disease in the UK. Circulation 100:1515–1520
  • Horai S, Murayama K, Hayasaka K, Matsubayashi S, Hattori Y, Fucharoen G, Harihara S, et al. 1996. mtDNA polymorphism in east Asian populations, with special reference to the peopling of Japan. Am J Hum Genet 59:579–590
  • Jia CQ, Zhao ZT, Wang LH, Hao FR, Feng YQ, Wang SM, Xu XF, Jia CX. 2003. Effects of G894T mutation in the endothelial nitric oxide synthase gene on blood pressure. Zhong Hua Liu Xing Bing Xue Za Zhi 24:36–39
  • Lacolley P, Gautier S, Poirier O, Pannier B, Cambien F, Benetos A. 1998. Nitric oxide synthase gene polymorphisms, blood pressure and aortic stiffness in normotensive and hypertensive subjects. J Hypertens 16:31–35
  • Lau J, Ioannidis JP, Schmid CH. 1997. Quantitative synthesis in systematic reviews. Ann Intern Med 127:820–826
  • Li DB, Hua Q, Pi L. 2004. Association of G894T polymorphism of endothelial nitric oxide synthase gene and essential hypertension. Zhonghua Gao Xue Ya Za Zhi 12:326–329
  • Li DJ, Liu H, Dong XL, Li W, Zhao YY. 2009a. Association study on polymorphism of endothelial nitric oxide synthase gene and hypertension. Guo Ji Yi Chuan Xue Za Zhi 32:17–18
  • Li DJ, Wu WF, Xu YL, Jiang XB, Jiang WJ, Wang SJ, Feng ZC, Zhang DF. 2009b. Effect of G894T mutation in the endothelial nitric oxide synthase gene and abnormality of waist to hip ratio on essential hypertension. Zhongguo Quan Ke Yi Xue Za Zhi 12:1173–1175
  • Li J, Cun Y, Tang WR, Wang Y, Li SN, Ouyang HR, Wu YR, et al. 2011. Association of eNOS gene polymorphisms with essential hypertension in the Han population in southwestern China. Genet Mol Res 10:2202–2212
  • Li YY. 2011. Endothelial nitric oxide synthase G894T gene polymorphism and essential hypertension in the Chinese population: a meta-analysis involving 11,248 subjects. Intern Med 50:2099–2106
  • Liang Q, Yang XL, Yang G, Cui JH. 2006. The relationship of angiotension-converting enzyme and endothelial nitric oxide synthase gene polymorphism in predisposition to essential hypertension. Lin Chuang He Shi Yan Yi Xue Za Zhi 5:861–862
  • Little RJA, Rubin DB. 1987. Statistical analysis with missing data. New York: Wiley. p 121
  • Liu HZ, Ha DW. 2002. Relationship between G894T polymorphism of endothelial nitric oxide synthase gene and essential hypertension. Zhongguo Xun Huan Za Zhi 17:361–363
  • Ma HX, Xie ZX, Niu YH, Li ZY, Zhou P. 2006. Single nucleotide polymorphisms in NOS3 A-922G, T-786C and G894T: a correlation study of the distribution of their allelic combinations with hypertension in Chinese Han population. Yi Chuan 28:3–10
  • Mancia G, De Backer G, Dominiczak A, Cifkova R, Fagard R. 2007. 2007 Guidelines for the Management of Arterial Hypertension: The Task Force for the Management of Arterial Hypertension of the European Society of Hypertension (ESH) and of the European Society of Cardiology (ESC). J Hypertens 25:1105–1187
  • Marsden PA, Heng HH, Scherer SW, Stewart RJ, Hall AV, Shi XM, Tsui LC, Schappert KT. 1993. Structure and chromosomal localization of the human constitutive endothelial nitric oxide synthase gene. J Biol Chem 268:17478–17488
  • McDonald DM, Alp NJ, Channon KM. 2004. Functional comparison of the endothelial nitric oxide synthase Glu298Asp polymorphic variants in human endothelial cells. Pharmacogenetics 14:831–839
  • Men C, Tang K, Lin G, Li J, Zhan Y. 2011. ENOS-G894T polymorphism is a risk factor for essential hypertension in China. Indian J Biochem Biophys 48:154–157
  • Miyamoto Y, Saito Y, Kajiyama N, Yoshimura M, Shimasaki Y, Nakayama M, Kamitani S, et al. 1998. Endothelial nitric oxide synthase gene is positively associated with essential hypertension. Hypertension 32:3–8
  • Moncada S, Higgs A. 1993. The l-arginine-nitric oxide pathway. N Engl J Med 329:2002–2012
  • Nejatizadeh A, Kumar R, Stobdan T, Goyal AK, Sikdar S, Gupta M, Javed S, Pasha MA. 2008. Endothelial nitric oxide synthase gene haplotypes and circulating nitric oxide levels significantly associate with risk of essential hypertension. Free Radic Biol Med 44:1912–1918
  • Niu WQ, Qi Y, Zhang LT, Qi YX, Wang B, Hou SQ, Zhai XY, Qiu CC. 2009. Endothelial nitric oxide synthase genetic variation and essential hypertension risk in Han Chinese: the Fangshan study. J Hum Hypertens 23:136–139
  • Omoto K, Saitou N. 1997. Genetic origins of the Japanese: a partial support for the dual structure hypothesis. Am J Phys Anthropol 102:437–446
  • Persu A, Stoenoiu MS, Messiaen T, Davila S, Robino C, El-Khattabi O, Mourad M, et al. 2002. Modifier effect of ENOS in autosomal dominant polycystic kidney disease. Hum Mol Genet 11:229–241
  • Petitti DB. 1994. Meta-analysis, decision analysis, and cost-effectiveness analysis. New York: Oxford University Press
  • Tan JC, Zhu ZM, Zhu SJ, Yu CQ, Wang L, Liu XL, Wang HY. 2003. The GNB3 and eNOS gene polymorphisms in patients with essential hypertension. Zhonghua Xin Xue Guan Bing Za Zhi 31:173–176
  • Tang W, Yang Y, Wang B, Xiao C. 2008. Association between a G894T polymorphism of eNOS gene and essential hypertension in Hani and Yi minority groups of China. Arch Med Res 39:222–225
  • Tang ZZ, Li JR, Yang JH. 2007. Relationship of endothelial nitric oxide synthase gene polymorphism with blood pressure, lipid profile and blood sugar level. Di-san Jun Yi Da Xue Xue Bao 29:448–450
  • Tesauro M, Thompson WC, Rogliani P, Qi L, Chaudhary PP, Moss J. 2000. Intracellular processing of endothelial nitric oxide synthase isoforms associated with differences in severity of cardiopulmonary diseases: cleavage of proteins with aspartate vs. glutamate at position 298. Proc Natl Acad Sci 6:2832–2835
  • Van Houwelingen HC, Arends LR, Stijnen T. 2002. Advanced methods in meta-analysis: multivariate approach and meta-regression. Stat Med 21:589–624
  • Wang C, Sun G, Yan XL, Ding YC, Chen M. 2006a. Association of polymorphisms G894T and T786C in the endothelial nitric oxide synthase gene with the risk of essential hypertension in Mongolian population. Zhongguo Fen Zi Xin Zang Bing Xue Za Zhi 6:81–84
  • Wang L, Chen D, Xue Y, Cheng Q, Zhu N. 2006b. Relationship between the Glu298Asp polymorphism of the endothelial nitric oxide synthase gene and essential hypertension. Guo Ji Yi Chuan Xue Za Zhi 29:336–340
  • Wang XH, Ni RZ. 2010. The Association between G894T Polymorphism of eNOS Gene and essential hypertension in Han group of Yunnan. Kunming Yi Xue Yuan Xue Bao 31:72–75
  • Wang ZQ, Mao YJ. 2009. Relationship between endothelial nitric oxide synthase and endothelin-2 gene polymorphisms and essential hypertension. Zhongguo Lao Nian Xue Za Zhi 29:2153–2155
  • Wen B, Li H, Lu D, Song X, Zhang F, He Y, Li F, et al. 2004. Genetic evidence supports demic diffusion of Han culture. Nature 431:302–305
  • Woolf B. 1995. On estimating the relation between blood group and disease. Ann Hum Genet 19:251–253
  • Xu XJ, Wang SZ, Lin RY, Wang XF, Liang XH, Wen H, Zhang ZX. 2004. Study of the G894T polymorphism of endothelial nitric oxide synthase gene with hypertension in Xinjiang Kazakh group. Zhonghuo Gao Xue Ya Za Zhi 12:131–134
  • Yoon Y, Song J, Hong SH, Kim JQ. 2000. Plasma nitric oxide concentrations and nitric oxide synthase gene polymorphisms in coronary artery disease. Clin Chem 46:1626–1630
  • Zdoukopoulos N, Doxani C, Messinis IE, Stefanidis I, Zintzaras E. 2011. Polymorphisms of the endothelial nitric oxide synthase (NOS3) gene in preeclampsia: a candidate-gene association study. BMC Pregnancy Childbirth 11:89–93
  • Zhang HF, Ma LY, Fang JR, Min H, Huang DZ. 2009. Relationship between G894T polymorphism of endothelial nitric oxide synthase gene and essential hypertension in dongxiang minority population. Shandong Yi Xue Za Zhi 49:14–16
  • Zhang HG, Chen YF, Ding M, Jin L, Case DT, Jiao YP, Wang XP, et al. 2010. Dermatoglyphics from all Chinese ethnic groups reveal geographic patterning. PLoS One 5:e8783
  • Zhang LP, Wang SZ, Zhao XX, Lian B, Wang XF, Lin RY, Lu DR, Jin L. 2006. Association between endothelial nitric oxide synthase gene (G894T) polymorphism and essential hypertension in Uygur populations. Zhonghua Xin Xue Guan Bing Za Zhi 34:403–406
  • Zhao F, Feng SX, Li GL, Ma H, Hu B. 2006a. Relationship between eNOS gene G894T mutation and hyperinsulinemia in patients with essential hypertension. Lin Chuang Xin Xue Guan Bing Za Zhi 22:413–416
  • Zhao Q, Su SY, Chen SF, Li B, Gu DF. 2006b. Association study of the endothelial nitric oxide synthase gene polymorphisms with essential hypertension in northern Han Chinese. Chin Med J (Engl) 119:1065–1071
  • Zhao SG, Hu RL, Niu GM, Zhang CY, Wang ZG, Jiang MF, Hu RL. 2008. Relationship between eNOS gene G894T polymorphism and essential hypertension complicating stroke in Mongmolian patients. Zhongguo Nao Xue Guan Bing Za Zhi 5:167–171
  • Zhou JZ, Chen Y, Zhou Y, Zhong WB, Li HW. 2010. Association of endothelial nitric oxide synthase gene polymorphism with essentiao hypertenson in Hans in Xinjiang. Lin Chuang Jun Yi Za Zhi 38:391–393
  • Zou FJ, Tang B, He F, Liu C, Wang G, Zhang Q, Lu XG, et al. 2011. Association of tag single-nucleotide polymorphisms of eNOS gene with essential hypertension in Han of Xinjiang. Zhongguo Bing Li Sheng Li Za Zhi 27:2049–2055

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.