References
- Veyrat-Follet C, Farinotti R, Palmer JL. (1997). Physiology of chemotherapy-induced emesis and anti-emetic therapy. Predictive models for evaluation of new compounds. Drugs, 53:206–34.
- Gregory RE, Ettinger DS. (1998). 5-HT3 receptor antagonists for the prevention of chemotherapy-induced nausea and vomiting. A comparison of their pharmacology and clinical efficacy. Drugs, 55:173–89.
- Scarantino CW, Ornitz RD, Hoffman LG. (1992). Radiation-induced emesis: Effects of ondansetron. Semin Oncol, 19:38–43.
- Wilde MI, Markham A. (1996). Ondansetron: A review of its pharmacology and preliminary clinical findings in novel applications. Drugs, 52:773–94.
- Roila F, Del Favero A. (1995). Ondansetron clinical pharmacokinetics. Clin Pharmacokinet, 29:95–109.
- Fromm MF. (2002). The influence of MDR1 polymorphisms on P-glycoprotein expression and function on humans. Adv Drug Deliv Rev, 54:1295–310.
- Hussain AA, Dakkuri A, Itoh S. (2000). Nasal absorption of ondansetron in rats: An alternative route of drug delivery. Cancer Chemother Pharmacol, 45:432–4.
- Cho E, Gwak H, Chun I. (2008). Formulation and evaluation of ondansetron nasal delivery systems. Int J Pharm, 349:101–7.
- Gungor S, Okyar A, Ertürk-Toker S, Baktir G, Ozsoy Y. (2009). Ondansetron-loaded biodegradable microspheres as a nasal sustained delivery system: In vitro/In vivo studies. Pharm Dev Technol (doi: 10.1080/10837450903148257).
- Mygind N, Dahl R. (1998). Anatomy, physiology and function of the nasal cavities in health and disease. Adv Drug Deliv Rev, 29:3–12.
- Ozsoy Y. (2008). Particulate carriers for nasal administration. In: Kumar MNVR, ed. Handbook of particulate drug delivery. CA: American Scientific Publisher, 143–64.
- Chowdary KPR, Rao YS. (2004). Mucoadhesive microspheres for controlled drug delivery. Biol Pharm Bull, 27:1717–24.
- Gavini E, Rassu G, Sanna V, Cossu M, Giunchedi P. (2005). Mucoadhesive microspheres for nasal administration of an antiemetic drug, metoclopramide: In-vitro/ex-vivo studies. J Pharm Pharmacol, 57:287–94.
- Gavini E, Hegge AB, Rassu G, Sanna V, Testa C, Pirisino G, . (2006). Nasal administration of carbamazepine using chitosan microspheres: In vitro/in vivo studies. Int J Pharm, 307:9–15.
- Lehr CM, Bouwstra JA, Schacht EH, Junginger HE. (1992). In vitro evaluation of mucoadhesive properties of chitosan and some other natural polymers. Int J Pharm, 78:43–8.
- Singla AK, Chawla M. (2001). Chitosan: Some pharmaceutical and biological aspects—an update. J Pharm Pharmacol, 53: 1047–67.
- Soane RJ, Frier M, Perkins AC, Jones NS, Davis SS, Illum L. (1999). Evaluation of the clearance characteristics of bioadhesive systems in humans. Int J Pharm, 178:55–65.
- Artursson P, Lindmark T, Davis SS, Illum L. (1994). Effect of chitosan on the permeability of monolayers of intestinal epithelial cells (Caco-2). Pharm Res, 11:1358–61.
- Sinha VR, Singla AK, Wadhawan S, Kaushik R, Kumria R, Bansal K, . (2004). Chitosan microspheres as a potential carrier for drugs. Int J Pharm, 274:1–33.
- Hafner A, Filipovic-Grcic J, Voinovich D, Jalsenjak I. (2007). Development and in vitro characterization of chitosan-based microspheres for nasal delivery of promethazine. Drug Dev Ind Pharm, 33:427–36.
- Asane GS, Nirmal SA, Rasal KB, Naik AA, Mahadik MS, Rao YM. (2008). Polymers for mucoadhesive drug delivery system: A current status. Drug Dev Ind Pharm, 34:1246–66.
- Hussain AA. (1998). Intranasal drug delivery. Adv Drug Deliv Rev, 29:39–49.
- Rowland M, Tozer TN. (1995). Clinical pharmacokinetics: Concepts and applications. 3rd ed. Philadelphia: Lippincott Williams & Wilkins.
- Giunchedi P, Juliano C, Gavini E, Cossu M, Sorrenti M. (2002). Formulation and in vivo evaluation of chlorhexidine buccal tablets prepared using drug-loaded chitosan microspheres. Eur J Pharm Biopharm, 53:233–9.
- Martinac A, Filipovic-Grcic J, Voinovich D, Perissutti B, Franceschinis E. (2005). Development and bioadhesive properties of chitosan-ethylcellulose microspheres for nasal delivery. Int J Pharm, 291:69–77.
- Akbuğa J, Durmaz G. (1994). Preparation and evaluation of crosslinked chitosan microspheres containing furosemide. Preparation and evaluation of cross-linked chitosan microspheres containing furosemide. Int J Pharm, 111:217–22.
- Jameela SR, Jayakrishnan A. (1995). Glutaraldehyde cross-linked chitosan microspheres as a long acting biodegradable drug delivery vehicle: Studies on the in vitro release of mitoxantrone and in vivo degradation of microspheres in rat muscle. Biomaterials, 16:769–75.
- He P, Davis SS, Illum L. (1998). In vitro evaluation of the mucoadhesive properties of chitosan microspheres. Int J Pharm, 166:75–88.
- He P, Davis SS, Illum L. (1999). Chitosan microspheres prepared by spray drying. Int J Pharm, 187:53–65.
- Ventura CA, Tommasini S, Crupi E, Giannone I, Cardile V, Musumeci T, . (2008). Chitosan microspheres for intrapulmonary administration of moxifloxacin: Interaction with biomembrane models and in vitro permeation studies. Eur J Pharm Biopharm, 68:235–44.
- Donovan MD, Huang Y. (1998). Large molecule and particulate uptake in the nasal cavity: The effect of size on nasal absorption. Adv Drug Deliv Rev, 29:147–55.
- Illum L, Fisher AN, Jabbal-Gill I, Davis SS. (2001). Bioadhesive starch microspheres and absorption enhancing agents act synergistically to enhance the nasal absorption of polypeptides. Int J Pharm, 222:109–19.
- Alpar HO, Somavarapu S, Atuah KN, Bramwell VW. (2005). Biodegradable mucoadhesive particulates for nasal and pulmonary antigen and DNA delivery. Adv Drug Deliv Rev, 57:411–30.