258
Views
22
CrossRef citations to date
0
Altmetric
Original Article

Insulin nanoparticles for transdermal delivery: preparation and physicochemical characterization and in vitro evaluation

, , , , &
Pages 1177-1185 | Received 09 Sep 2009, Accepted 11 Feb 2010, Published online: 01 Apr 2010

References

  • Gale EAM. (2009). The discovery of type 1 diabetes. Diabetes, 50(2):217–26.
  • Vivian Fonseca M. (2006). The role of basal insulin therapy in patients with type 2 diabetes mellitus. Insulin, 1(2):51–60.
  • Chen H, Zhu H, Zheng J, Mou D, Wan J, Zhang J, . (2009). Iontophoresis-driven penetration of nanovesicles through microneedle-induced skin microchannels for enhancing transdermal delivery of insulin. J Control Release, 139(1):63–72.
  • Skyler JS, Weinstock RS, Raskin P, Yale JF, Barrett E, Gerich JE, . (2005). Use of inhaled insulin in a basal/bolus insulin regimen in type 1 diabetic subjects: A 6-month, randomized, comparative trial. Diab Care, 28(7):1630–5.
  • Klingler C, Müller BW, Steckel H. (2009). Insulin-micro- and nanoparticles for pulmonary delivery. Int J Pharm, 377(1–2): 173–9.
  • Singh B, Chauhan N. (2009). Modification of psyllium polysaccharides for use in oral insulin delivery. Food Hydrocolloid, 23(3):928–35.
  • Lee Y-C, Simamora P, Pinsuwanc S, Yalkowskya SH. (2002). Review on the systemic delivery of insulin via the ocular route. Int J Pharm, 233(1–2):1–18.
  • Hosny EA (1999). Relative hypoglycemia of rectal insulin suppositories containing deoxycholic acid, sodium taurocholate, polycarbophil, and their combinations in diabetic rabbits. Drug Dev Ind Pharm, 25(6):745–52.
  • El-Sayed Khafagy MM, Onukia Y, Takayamaa K. (2007). Current challenges in non-invasive insulin delivery systems: A comparative review. Adv Drug Deliv Rev, 59(15):1521–46.
  • Prausnitz MR, Mitragotri S, Langer R. (2004). Current status and future potential of transdermal drug delivery. Nat Rev Drug Discov, 3(2):115–24.
  • Prausnitz MR, Mitragotri S, Langer R. (2001). Overcoming skin's barrier: The search for effective and user-friendly drug delivery. Diab Technol Ther, 3(2):233–6.
  • El Maghraby GM, Williams AC, Barry BW. (2004). Interactions of surfactants (edge activators) and skin penetration enhancers with liposomes. Int J Pharm, 276(1–2):143–61.
  • Kalia YN, Naik A, Garrison J, Guy RH. (2004). Iontophoretic drug delivery. Drug Deliv, 56(5):619–58.
  • Lavon I, Kost J. (2004). Ultrasound and transdermal drug delivery. Drug Discov Today, 9(15):670–6.
  • Prausnitz MR. (2004). Microneedles for transdermal drug delivery. Adv Drug Deliv, 56(5):581–7.
  • Reverchon E, Adami R. (2006). Nanomaterials and supercritical fluids. J Supercrit Fluids, 37(1):1–22.
  • Miguel AMF, Gamse T, Cocero MJ. (2006). Supercritical anti-solvent precipitation of lycopene: Effect of the operating parameters. J Supercrit Fluids, 36(3):225–35.
  • Catchpole OJ, Grey JB, Mitchell KA, Lan JS. (2004). Supercitical antisolvent fractionation of propolis tincture. J Supercrit Fluids, 29(1–2):97–106.
  • Zhiyi L, Jingzhi J, Xuewu L, Huihua T, Wei W. (2009). Experimental investigation on the micronization of aqueous cefadroxil by supercritical fluid technology. J Supercrit Fluids, 48(3):247–52.
  • Huang Z, Sun G-B, Chiew YC, Kawi S. (2006). Formation of ultrafine aspirin particles through rapid expansion of supercritical solutions (RESS). Powder Technol, 160(2): 127–34.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.