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Research Article

Preparation of cationic biodegradable dextran microspheres loaded with BSA and study on the mechanism of protein loading

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Pages 653-658 | Received 25 May 2010, Accepted 16 May 2011, Published online: 03 Apr 2012

References

  • Kumar MNVR. (2000). Nano and microparticles as controlled drug delivery devices. J Pharm Pharmaceut Sci, 3:234–258.
  • Sinha VR, Trehan A. (2003). Biodegradable microspheres for protein delivery. J Control Release, 90:261–280.
  • Hoyer H, Perera G, Bernkop-Schnurch A. (2010). Noninvasive delivery systems for peptides and proteins in osteoporosis therapy: A retroperspective. Drug Dev Ind Pharm, 36:31–44.
  • Yoncheva K, Lambov N, Miloshev S. (2009). Modification of biodegradable poly(malate) and poly(lactic-co-glycolic acid) microparticles with low molecular polyethylene glycol. Drug Dev Ind Pharm, 35:449–454.
  • Stenekes RJ, Franssen O, van Bommel EM, Crommelin DJ, Hennink WE. (1998). The preparation of dextran microspheres in an all-aqueous system: effect of the formulation parameters on particle characteristics. Pharm Res, 15:557–561.
  • Franssen O, Vandervennet L, Roders P, Hennink WE. (1999). Degradable dextran hydrogels: controlled release of a model protein from cylinders and microspheres. J Control Release, 60:211–221.
  • Cadée JA, Brouwer LA, den Otter W, Hennink WE, van Luyn MJ. (2001). A comparative biocompatibility study of microspheres based on crosslinked dextran or poly(lactic-co-glycolic)acid after subcutaneous injection in rats. J Biomed Mater Res, 56:600–609.
  • Vlugt-Wensink KD, Meijer YJ, van Steenbergen MJ, Verrijk R, Jiskoot W, Crommelin DJ et al. (2007). Effect of excipients on the encapsulation efficiency and release of human growth hormone from dextran microspheres. Eur J Pharm Biopharm, 67:589–596.
  • Sajadi Tabassi SA, Tafaghodi M, Jaafari MR. (2008). Induction of high antitoxin titers against tetanus toxoid in rabbits by intranasal immunization with dextran microspheres. Int J Pharm, 360:12–17.
  • Cai C, Bakowsky U, Rytting E, Schaper AK, Kissel T. (2008). Charged nanoparticles as protein delivery systems: a feasibility study using lysozyme as model protein. Eur J Pharm Biopharm, 69:31–42.
  • Raemdonck K, Thienen TGV, Vandenbroucke RE, Sanders NN, Demeester J, Smedt SCD. (2008). Dextran microgels for time-controlled delivery of siRNA. Adv Funct Mater, 18:993–1001.
  • T, Kopac K, Bozgeyik, J Yener. (2008). Effect of pH and temperature on the adsorption of bovine serum albumin onto titanium dioxide. Colloids Surf A Physicochem Eng Aspects, 322:19–28.
  • Vlugt-Wensink KD, Vlugt TJ, Jiskoot W, Crommelin DJ, Verrijk R, Hennink WE. (2006). Modeling the release of proteins from degrading crosslinked dextran microspheres using kinetic Monte Carlo simulations. J Control Release, 111:117–127.
  • DijkWolthuis WNEV, Tsang SKY, KettenesvandenBosch JJ, Hennink WE. (1997). A new class of polymerizable dextrans with hydrolysable groups: Hydroxyethyl methacrylated dextran with and without oligolactate spacer. Polymer, 38:6235–6242.
  • Wetering PVD, Zuidam NJ, Steenbergen MJD, Houwen OVD, Underberg WJM, Hennink WE. (1998). A mechanistic study of the hydrolytic stability of poly(2-(dimethylamino)ethyl methacrylate). Macromolecules, 31:8063–8068.
  • Wittemann A, Ballauff M. (2004). Secondary structure analysis of proteins embedded in spherical polyelectrolyte brushes by FT-IR spectroscopy. Anal Chem, 76:2813–2819.
  • Czeslik C, Jansen R, Ballauff M, Wittemann A, Royer CA, Gratton E et al. (2004). Mechanism of protein binding to spherical polyelectrolyte brushes studied in situ using two-photon excitation fluorescence fluctuation spectroscopy. Phys Rev E Stat Nonlin Soft Matter Phys, 69:021401.
  • Rosenfeldt S, Wittemann A, Ballauff M, Breininger E, Bolze J, Dingenouts N. (2004). Interaction of proteins with spherical polyelectrolyte brushes in solution as studied by small-angle x-ray scattering. Phys Rev e Stat Nonlin Soft Matter Phys, 70:061403.
  • Haupt B, Neumann T, Wittemann A, Ballauff M. (2005). Activity of enzymes immobilized in colloidal spherical polyelectrolyte brushes. Biomacromolecules, 6:948–955.
  • Cadée JA, de Groot CJ, Jiskoot W, den Otter W, Hennink WE. (2002). Release of recombinant human interleukin-2 from dextran-based hydrogels. J Control Release, 78:1–13.
  • Stenekes RJ, De Smedt SC, Demeester J, Sun G, Zhang Z, Hennink WE. (2000). Pore sizes in hydrated dextran microspheres. Biomacromolecules, 1:696–703.
  • Van Tomme SR, Hennink WE. (2007). Biodegradable dextran hydrogels for protein delivery applications. Expert Rev Med Devices, 4:147–164.

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