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Research Article

Synthesis and in vitro release study of ibuprofen-loaded gelatin graft copolymer nanoparticles

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Pages 61-65 | Received 20 May 2012, Accepted 30 Oct 2012, Published online: 18 Dec 2012

References

  • Maincent P, Le Verge R, Sado P, et al. Disposition kinetics and oral bioavailability of vincamine-Loaded polyalkyl cyanoacrylate nanoparticles. J. Pharm Sci 1986;75:955–8
  • Damgé C, Maincent P, Ubrich N. Oral delivery of insulin associated to polymeric nanoparticles in diabetic rats. J Control Release 2007;117:163–70
  • Sheik-Hassan A, Socha M, Lamprecht A, et al. Effect of the microencapsulation of nanoparticles on the reduction of burst release. Int J Pharm 2007;344:53–61
  • Sheik-Hassan A, Sapin A, Leroy P, et al. Composite microparticles with in vivo reduction of the burst release effect. Eur J Pharm Biopharm 2009;73:337–44
  • Ikada Y, Tabata Y. Protein release from gelatin matrices. Adv Drug Delivery Rev 1998;31:287–301
  • Chain YW. Novel drug delivery systems. 2nd ed. New York: Marcel Dekker; 1992
  • Sakuma S, Hayashi M, Akashi M. Design of nanoparticles composed of graft copolymers for oral peptide delivery. Adv Drug Deliv Rev 2001;47:21–37
  • Kreuter J, ed. Nanoparticles. In: Colloidal drug delivery systems. New York: Marcel Dekker; 1994:219–342
  • Carbone AL, Uhrich KE. Design and synthesis of fast-degrading poly(anhydride-esters). Macromol Rapid Commun 2009;30:1021–6
  • Sakuma S, Ohshima H, Kondo TJ. Binding constants of metal cations to and hamaker constant for poly(N,N-l-lysinediylterephthaloyl) microcapsules. Colloid Interface Sci 1990;135:455–60
  • Brigger I, Duberne, C, Couveur P. Nanoparticles in cancer therapy and diagnosis. Adv Drug Del Rev 2002;54:631–51
  • Hans ML, Lowman AM. Biodegradable nanoparticles for drug delivery and targeting. Curr Opin Solid State Mater Sci 2002;6:319–27
  • Panyam J, Labhasetwar V. Biodegradable nanoparticles for drug and gene delivery to cells and tissue. Adv Drug Del Rev 2003;55:329–47
  • Nakada Y, Fattal E, Foulquier M, Couvreur P. Pharmacokinetics and biodistribution of oligonucleotide adsorbed onto poly(isobutylcyanoacrylate) nanoparticles after intravenous administration in mice. Pharm Res 1996;13:38–43
  • Kuijpers AJ, Van Wachem PB, Van Luyn MJ, et al. In vivo compatibility and degradation of crosslinked gelatin gels incorporated in knitted Dacron. J Biomed Mater Res 2000; 51:136–45
  • Haroun AA, El Toumy SA. Effect of natural polyphenols on physicochemical properties of crosslinked gelatin-based polymeric biocomposite. J Appl Polym Sci 2010;116:2825–32
  • Haroun AA, Gamal-Eldeen A, Harding DRK. Preparation, characterization and in vitro biological study of biomimetic three-dimensional gelatin–montmorillonite/cellulose scaffold for tissue engineering. J Mater Sci: Mater Med 2009;20:2527–40
  • Kuijpers AJ, Engbers GH, Krijgsveld J, et al. Crosslinking and characterization of gelatin matrices for biomedical applications. J Biomater Sci Polym Ed 2000;11:225–43
  • Dinarvand R, Sepehri N, Manoochehri S, et al. Polylactide-co-glycolide nanoparticles for controlled delivery of anticancer agents. Int J Nanomed 2011;6:877–95
  • Stevens KR, Einerson NJ, Burmania JA, Kao WJ. In vivo biocompatibility of gelatin-based hydrogels and interpenetrating networks. Biomater Sci Polymer Edn 2002;13:1353–66
  • Mario Y, Chakfe N, Deng X, et al. Carbodiimide cross-linked gelatin: a new coating for porous polyester arterial prostheses. Biomaterials 1995;16:1131–9
  • Haroun AA, Migonney V. Synthesis and in vitro evaluation of gelatin/hydroxyapatite graft copolymers to form bionanocomposites. Int J Biol Macromol 2010;46:310–16
  • Haroun AA, El-Halawany NR. Encapsulation of bovine serum albumin within β-cyclodextrin/gelatin-based polymeric hydrogel for controlled protein drug release. IRBM 2010;31:234–41
  • Kang HW, Tabata Y, Ikada, Y. Fabrication of porous gelatin scaffolds for tissue engineering. Biomaterials 1999;20:1339–44
  • Tabata Y, Morimoto K, Katsumata H, et al. Surfactant-free preparation of biodegradable hydrogel microspheres for protein release. J Bioact Compat Polym 1999;14:371–84
  • Ferreira L, Vidal MM, Gil MH. Evaluation of poly(2-hydroxyethyl methacrylate) gels as drug delivery systems at different pH values. Int J Pharm 2000;194:169–80
  • Arida AI, Amoro B, Jaghbir M, et al. Development of sustained release ibuprofen microspheres using solvent evaporation technique. Arch Pharm 1999;332:405–7
  • Wolfe MM. Gastrointestinal toxicity of non steroidal anti-inflammatory drugs. N Engl J Med 1999;340:1888–99
  • Bajpai AK, Choubey J. Design of gelatin nanoparticles as swelling controlled delivery system for chloraquine phosphate. J Mater Sci: Mater Med 2006;17:345–58

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