525
Views
47
CrossRef citations to date
0
Altmetric
Research Article

Stability of sulforaphane for topical formulation

, , , &
Pages 494-502 | Received 27 Sep 2012, Accepted 17 Jan 2013, Published online: 23 Apr 2013

References

  • Jemal A, Siegel R, Ward E, et al. Cancer statistics. CA Cancer J Clin 2007;57:43–66
  • Clydesdale GJ, Dandie G, Mueller HK. Ultraviolet light induced injury: immunological and inflammatory effects. Immunol Cell Biol 2001;79:547–68
  • Dickinson SE, Melton TF, Olson ER, et al. Inhibition of activator protein-1 by sulforaphane involves interaction with cysteine in the cFos DNA-binding domain: implications for chemoprevention of UVB-induced skin cancer. Cancer Res 2009;69:7103–10
  • Juge N, Mithen RF, Traka M. Molecular basis for chemoprevention by sulforaphane: a comprehensive review. Cell Mol Life Sci 2007;64:1105–27
  • Chen W, Borchers AH, Dong Z, et al. UVB irradiation-induced activator protein-1 activation correlates with increased c-fos gene expression in a human keratinocyte cell line. J Biol Chem 1998;273:32176–81
  • Cooper SJ, MacGowan J, Ranger-Moore J, et al. Expression of dominant negative c-jun inhibits ultraviolet B-induced squamous cell carcinoma number and size in an SKH-1 hairless mouse model. Mol Cancer Res 2003;11:848–54
  • Barthelman M, Chen W, Gensler HL, et al. Inhibitory effects of perillyl alcohol on UVB-induced murine skin cancer and AP-1 transactivation. Cancer Res 1998;58:711–16
  • Li JJ, Dong Z, Dawson MI, Colburn NN. Inhibition of tumor promoter-induced transformation by retinoids that transrepress AP-1 without transactivating retinoic acid response element. Cancer Res 1996;56:483–9
  • Dinkova-Kostova AT, Jenkins SN, Fahey JW, et al. Protection against UV-light-induced skin carcinogenesis in SKH-1 high-risk mice by sulforaphane-containing broccoli sprout extracts. Cancer Lett 2006;240:243–52
  • Dinkova-Kostova AT, Fahey JW, Wade KL, et al. Induction of the phase 2 response in mouse and human skin by sulforaphane-containing broccoli sprout extracts. Cancer Epidemiol Biomarkers Prev 2007;16:847–51
  • Talalay P, Fahey JW, Healy ZR, et al. Sulforaphane mobilizes cellular defenses that protect skin against damage by UV radiation. Proc Natl Acad Sci USA 2007;104:17500–5
  • ACD/Chemsketch for Windows, Version 12.0, Advanced Chemistry Development, Inc
  • Jin Y, Wang M, Rosen RT, Ho CT. Thermal degradation of sulforaphane in aqueous solution. J Agric Food Chem 1999;47:3121–3
  • Gupta A, Myrdal PB. Development of a perillyl alcohol topical cream formulation. Int J Pharm 2004;269:373–83
  • Rincon M, Flavell RA. AP-1 transcriptional activity requires both T-cell receptor-mediated and co-stimulatory signals in primary T lymphocytes. EMBO J 1994;13:4370–81
  • Bachelor MA, Cooper SJ, Sikorski ET, Bowden GT. Inhibition of p38 mitogen-activated protein kinase and phosphatidylinositol 3-kinase decreases UVB-induced activator protein-1 and cyclooxygenase-2 in a SKH-1 hairless mouse model. Mol Cancer Res 2005;3:90–9
  • Xiao Q, Liang H, Yuan Q-P. Effect of temperature, pH and light on the stability of sulforaphane solution. Chin Pharm J 2009;43:193–6

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.