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Research Articles

Co-delivery of paclitaxel and α-tocopherol succinate by novel chitosan-based polymeric micelles for improving micellar stability and efficacious combination therapy

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Pages 1137-1147 | Received 28 Oct 2013, Accepted 06 Jun 2014, Published online: 14 Jul 2014

References

  • Nishiyama N, Kataoka K. Current state, achievement, and future prospects of polymeric micelles as nanocarriers for drug and gene delivery. Pharmacol Ther 2006;112:630–48
  • Yao Z, Zhang C, Ping Q, Yu L. A series of novel chitosan derivatives: synthesis, characterization, and micellar solubilization of paclitaxel. Carbohydr Polymer 2007;68:781–92
  • Ouahab A, Shao Ch, Shen Y, Tu J. Development and characterization of stabilized double loaded mPEG-PDLLA micelles for simultaneous delivery of paclitaxel and docetaxel. Drug Dev Ind Pharm 2014;40:860–8
  • Liang H, Yang Q, Deng L, et al. Phospholipid–Tween 80 mixed micelles as an intravenous delivery carrier for paclitaxel. Drug Dev Ind Pharm 2011;37:597–605
  • Attia A, Yang C, Tan J, et al. The effect of kinetic stability on biodistribution and anti-tumor efficacy of drug-loaded biodegradable polymeric micelles. Biomaterials 2013;34:3132–40
  • Yang C, Attia E, Tan PK, et al. The role of non-covalent interactions in anticancer drug loading and kinetic stability of polymeric micelles. Biomaterials 2012;33:2971–9
  • Lua Y, Parka K. Polymeric micelles and alternative nanonized delivery vehicles for poorly soluble drugs. Int J Pharmaceutic 2013;453:198–214
  • Öcal H, Arıca-Yegin B, Vural I, et al. 5-Fluorouracil-loaded PLA/PLGA PEG–PPG–PEG polymeric nanoparticles: formulation, in vitro characterization and cell culture studies. Drug Dev Ind Pharm 2014;40:560–7
  • Wang F, Chen Y, Zhang D, et al. Folate-mediated targeted and intracellular delivery of paclitaxel using a novel deoxycholic acid-O-carboxymethylated chitosan–folic acid micelles. Int J Nanomedicine 2012;7:325–37
  • Hu FQ, Ren GF, Yuan H, et al. Shell cross-linked stearic acid grafted chitosan oligosaccharide self-aggregated micelles for controlled release of paclitaxel. Colloids Surf B Biointerfaces 2006;50:97–103
  • Yang C, Tan JPK, Cheng W, et al. Supramolecular nanostructures designed for high cargo loading capacity and kinetic stability. Nano Today 2010;5:515–23
  • Voets IK, Keizer A, Stuart MAC, et al. Irreversible structural transitions in mixed micelles of oppositely charged diblock copolymers in aqueous solution. Macromolecules 2007;40:2158–64
  • Hu FQ, Wu X, Du Y, et al. Cellular uptake and cytotoxicity of sell crosslinked stearic acid-grafted chitosan oligosaccharide micelles encapsulating doxorubicin. Eur J Pharmaceutic Biopharmaceutic 2008;69:117–25
  • Alani WG, Bae Y, Deepa A, Kwon S. Polymeric micelles for the pH-dependent controlled, continuous low dose release of paclitaxel. Biomaterials 2010;31:1765–72
  • Hu FQ, Liu LN, Du YZ, Yuan H. Synthesis and antitumor activity of doxorubicin conjugated stearic acid-g-chitosan oligosaccharide polymeric micelles. Biomaterials 2009;30:6955–63
  • Prasad KN, Kumar B, Yan XD, et al. Tocopheryl succinate, the most effective form of vitamin E for adjuvant cancer treatment: a review. J Am Coll Nutr 2003;22:108–17
  • Lim S, Choi M, Kim M, Kim J. Tocopheryl succinate potentiates the paclitaxel-induced apoptosis through enforced caspase 8 activation in human H460 lung cancer cells. Exp Mol Med 2009;41:737–45
  • Zhang X, Peng X, Yu W, et al. Alpha-tocopheryl succinate enhances doxorubicin-induced apoptosis in human gastric cancer cells via promotion of doxorubicin influx and suppression of doxorubicin efflux. Cancer Let 2011;307:174–81
  • Youk HJ, Lee E, Choi MK, et al. Enhanced anticancer efficacy of α-tocopheryl succinate by conjugation with polyethylene glycol. J Control Release 2005;107:43–52
  • Hrzenjak A, Reicher H, Wintersperger A, et al. Inhibition of lung carcinoma cell growth by high density lipoprotein-associated α-tocopheryl-succinate. Cell Mol Life Sci 2004;61:1520–31
  • Kogure K, Manabe S, Hama S, et al. Potentiation of anti-cancer effect by intravenous administration of vesiculated α-tocopheryl hemisuccinate on mouse melanoma in vivo. Cancer Lett 2003;192:19–24
  • Quinones JP, Gothelf KV, Kjem J, et al. Self-assembled nanoparticles of modified-chitosan conjugates for the sustained release of dl-α-tocopherol. Carbohydr Polym 2013;92:856–64
  • Noh SM, Han SE, Shim G, et al. Tcopheryl oligochitosan based self-assembling oligomersomes for siRNA delivery. Biomaterials 2011;32:849–57
  • Lo CL, Huang CK, Lin KM, Hsiue GH. Mixed micelles formed from graft and diblock copolymers for application in intracellular drug delivery. Biomaterials 2007;28:1225–8
  • Kim H, Emoto K, Lijima M, et al. Core-stabilized polymeric micelle as potential drug carrier: increased solubilization of taxol. Poly Adv Technol 1999;10:647–54
  • Martínez Sancho C, Herrero Vanrell R, Negro S. Determination of vitamin E acid succinate in biodegradable microspheres by reversed-phase, high-performance liquid chromatography. J Chromatogr Sci 2004;42:4348–52
  • Du Y-Z, Wang L, Hong Y, Hu F-Q. Linoleic acid-grafted chitosan oligosaccharide micelles for intracellular drug delivery and reverse drug resistance of tumor cells. Int J Biol Macromol 2011;48:215–22
  • Emami J, Rezazadeh M, Varshosaz J, et al. Formulation of LDL targeted nanostructured lipid carriers loaded with paclitaxel: a detailed study of preparation, freeze drying condition, and in vitro cytotoxicity. J Nanomaterials 2012;2012: Article ID 358782, doi: 10.1155/2012/358782
  • Du YZ, Weng Q, Yuan H, Hu FQ. Synthesis and antitumor activity of stearate-g-dextran micelles for intracellular doxorubicin delivery. ACS Nano 2010;11:6894–902
  • Shin HC, Alani WG, Rao DA, et al. Multi-drug loaded polymeric micelles for simultaneous delivery of poorly soluble anticancer drugs. J Control Release 2009;140:294–300
  • Janoff AS, Kurtz CL, Jablonski RL, et al. Characterization of cholesterol hemisuccinate and α-tocopherol hemisuccinate vesicles. Biochim Biophys Acta 1988;941:165–75
  • Hama S, Utsumi S, Fukuda Y, et al. Development of a novel drug delivery system consisting of an antitumor agent tocopheryl succinate. J Control Release 2012;161:843–51
  • Yi-Qing Y, Yang F, Hu FQ, et al. Core-modified chitosan-based polymeric micelles for controlled release of doxorubicin. Int J Pharmaceut 2008;35:2294–301
  • Gao Y, Li LB, Zhai G. Preparation and characterization of/TPGS mixed micelles for solubilization of camptotecin. Colloids Surf B Biointerfaces 2008;64:194–9
  • Kogure K, Manabe S, Hama S, et al. Potentiation of anti-cancer effect by intravenous administration of vesiculated α-tocopheryl hemisuccinate on mouse melanoma in vivo. Cancer Lett 2003;192:19–24
  • Pussinen PJ, Lindner H, Glatter O, et al. Lipoprotein-associated α-tocopheryl-succinate inhibits cell growth and induces apoptosis in human MCF-7 and HBL-100 breast cancer cells. Biochim Biophys Acta 2000;1485:129–44

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