Sugars as solid dispersion carrier to improve solubility and dissolution of the BCS class II drug: clotrimazole

References

• Chiou WL, Riegelman S. Pharmaceutical applications of solid dispersion systems. J Pharm Sci 1971;60:1281–302
   PubMed Web of Science ®Google Scholar
• Vasconcelos T. Sarmento B, Costa P. Solid dispersions as strategy to improve oral bioavailability of poor water soluble drugs. Drug Discov Today 2007;12:1068–75
   PubMed Web of Science ®Google Scholar
• Passerini N, Albertini B, Gonzalez-Rodríguez ML, et al. Preparation and characterisation of ibuprofen–poloxamer 188 granules obtained by melt granulation. Eur J Pharm Sci 2002;15:71–8
   PubMed Web of Science ®Google Scholar
• Jagdale S, Patil S, Kuchekar B, Chabukswar A. Preparation and characterization of metformin hydrochloride Compritol 888 ATO solid dispersion. J Young Pharm 2011;3:197–204
   PubMedGoogle Scholar
• Damian F, Blaton N, Naesens L, et al. Physicochemical characterization of solid dispersions of the antiviral agent UC-781 with polyethylene glycol 6000 and Gelucire 44/14. Eur J Pharm Sci 2000;10:311–22
   PubMed Web of Science ®Google Scholar
• Van den Mooter G, Weuts I, De Ridder T, Blaton N. Evaluation of Inutec SP1 as a new carrier in the formulation of solid dispersions for poorly soluble drugs. Int J Pharm 2006;316:1–6
   PubMed Web of Science ®Google Scholar
• Kalivoda A, Fischbach M, Kleinebudde P. Application of mixtures of polymeric carriers for dissolution enhancement of oxeglitazar using hot melt extrusion. Int J Pharm 2012;439:145–56
   PubMed Web of Science ®Google Scholar
• Allen LV, Ju Yanchick VA, Maness DD. Dissolution rates of corticosteroids utilizing sugar glass dispersions. J Pharm Sci 1977;66:496–7
   Web of Science ®Google Scholar
• Allen LV, Ju Yanchick VA, Maness DD. Dissolution rates of hydrocortisone and prednisone utilizing sugar solid dispersions systems in tablet form. J Pharm Sci 1978;67:979–81
   PubMed Web of Science ®Google Scholar
• Attia MA, Habib FS. Dissolution rates of carbamazepine and nitrazepam utilizing sugar solid dispersion system. Drug Dev Ind Pharm 1985;11:1957–69
   Web of Science ®Google Scholar
• Mummaneni V, Vasavada RC. Solubilization and dissolution of famotidine from solid glass dispersion of xylitol. Int J Pharm 1990;66:71–7
   Web of Science ®Google Scholar
• Eva S, Christer N. Physicochemical aspects of drug release. XI. Tableting properties of solid dispersion using xylitol as carrier material. Int J Pharm 1990;67:139–53
   Google Scholar
• Arias MJ, Gines JM, Moyano JR, et al. Influence of preparation method of solid dispersion on their dissolution rate: study of triamterene –d-mannitol system. Int J Pharm 1995;123:25–31
   Web of Science ®Google Scholar
• Arias MJ, Moyano JR, Gine JM. Study by DSC and HSM of the oxazepam -PEG 6000 and oxazepam-d-mannitol systems: application to the preparation of solid dispersions. Thermochim Acta 1998;321:33–41
   Web of Science ®Google Scholar
• Langer M, Höltje M, Urbanetz NA, et al. Investigations on the predictability of the formation of glassy solid solutions of drugs in sugar alcohols. Int J Pharm 2003;252:167–79
   PubMed Web of Science ®Google Scholar
• van Drooge DJ, Hinrichs WLJ, Frijlink HW. Anomalous dissolution behaviour of tablets prepared from sugar glass-based solid dispersions. J Control Rel 2004;97:441–52
   PubMed Web of Science ®Google Scholar
• Natalija Z, Ales O, Marjan B, Stane S. Physical properties and dissolution behaviour of nifedipine/mannitol solid dispersions prepared by hot melt method. Int J Pharm 2004;291:51–8
   PubMed Web of Science ®Google Scholar
• Al-Hamidi H, Alison AE, Mohammad AM, Ali N. To enhance dissolution rate of poorly water-soluble drugs: glucosamine hydrochloride as a potential carrier in solid dispersion formulations. Colloid Surface B 2010;76:170–8
   PubMed Web of Science ®Google Scholar
• Singh G, Chhabra G, Pathak K. Dissolution behaviour and thermodynamic stability of fused-sugar dispersions of poorly water-soluble drug. Dissolut Technol 2011;18:62–70
   Web of Science ®Google Scholar
• Abhisekh D, Amit Kumar N, Biswaranjan M, Satyabrata P. Solubility and dissolution enhancement of etoricoxib by solid dispersion technique using sugar carriers. ISRN Pharm 2011;2011:1–8
   Google Scholar
• Realdon N, Ragazzi E. Effect of drug solubility on in vitro availability rate from suppositories with polyethylene glycol excipients. Pharmazie 2001;56:163–7
   PubMed Web of Science ®Google Scholar
• Madhusudhan B, Rambhan D, Gudsoorkar VR, et al. Development and Evaluation of antifungal activity of O/W type Creams Containing solid dispersion of Clotrimazole. Indian J Pharm Sci 1999;61:346–9
   Google Scholar
• Balata G, Mahdi M, Bakera R. Improvement of solubility and dissolution properties of clotrimazole by solid dispersion and inclusion complexes. Ind J Pharm Sci 2013;73:517–26
   Web of Science ®Google Scholar
• Ahmed MO, El-Gibaly I, Ahmed SM. Effect of cyclodextrins on the physicochemical properties and antimycotic activity of clotrimazole. Int J Pharm 1998;171:111–21
   Web of Science ®Google Scholar
• Higuchi T, Connors KA. Phase solubility techniques. Adv Anal Chem Instrum 1965;4:207–12
   Google Scholar
• Suhagia B, Patel HM, Shah SA, et al. Preparation and characterization of etoricoxib-polyethylene glycol 4000 plus Polyvinylpyrrolidone K30 solid dispersions. Acta Pharm 2006;56:285–98
   PubMedGoogle Scholar
• Ceschel GC, Maffei P, Lombardi Borgia S, et al. Development of a mucoadhesive dosage form for vaginal administration. Drug Dev Ind Pharm 2001;27:541–7
   PubMed Web of Science ®Google Scholar
• Margareth RC, Loebenberg R, Almukainzi M. Simulated biological fluids with possible application in dissolution testing. Dissolut Technol 2011;18:15–28
   Web of Science ®Google Scholar
• Zhang Y, Huo M, Zhou J, Zou A. DDSolver: an add-in program for modeling and comparison of drug dissolution profiles. AAPS J 2010;12:263–71
   PubMed Web of Science ®Google Scholar
• Leuner C, Dressman J. Improving drug solubility for oral delivery using solid dispersions. Eur J Pharm Biopharm 2000;50:47–60
   PubMed Web of Science ®Google Scholar