Histological assessment of follicular delivery of flutamide by solid lipid nanoparticles: potential tool for the treatment of androgenic alopecia

References

• Aggarwal S, Thareja S, Verma A, et al. An overview on 5α-reductase inhibitors. Steroids 2010;75:109–53
   PubMed Web of Science ®Google Scholar
• Pérez-Ornelas V, Cabeza M, Bratoeff E, et al. New 5α-reductase inhibitors: in vitro and in vivo effects. Steroids 2005;70:217–24
   PubMed Web of Science ®Google Scholar
• Kaufman KD. Androgens and alopecia. Mol Cell Endocrinol 2002;198:89–95
   PubMed Web of Science ®Google Scholar
• Sintov A, Serafimovich S, Gilhar A. New topical antiandrogenic formulations can stimulate hair growth in human bald scalp grafted onto mice. Int J Pharm 2000;194:125–34
   PubMed Web of Science ®Google Scholar
• Castelo-Branco C, Moyano D, Gómez O, et al. Long-term safety and tolerability of flutamide for the treatment of hirsutism. Fertil Steril 2009;91:1183–8
   PubMed Web of Science ®Google Scholar
• Cusan L, Dupont A, Bélanger A, et al. Treatment of hirsutism with the pure antiandrogen flutamide. J Am Acad Dermatol 1990;23:462–9
   PubMed Web of Science ®Google Scholar
• Falsetti L, Gambera A. Comparison of finasteride and flutamide in the treatment of idiopathic hirsutism. Fertil Steril 1999;72:41–6
   PubMed Web of Science ®Google Scholar
• Inal MM, Yildirim Y, Taner CE. Comparison of the clinical efficacy of flutamide and spironolactone plus Diane 35 in the treatment of idiopathic hirsutism: a randomized controlled study. Fertil Steril 2005;84:1693–7
   PubMed Web of Science ®Google Scholar
• Tabbakhian M, Tavakoli N, Jaafari MR, et al. Enhancement of follicular delivery of finasteride by liposomes and niosomes: 1. In vitro permeation and in vivo deposition studies using hamster flank and ear models. Int J Pharm 2006;323:1–10
   PubMed Web of Science ®Google Scholar
• Alnasif N, Zoschke C, Fleige E, et al. Penetration of normal, damaged and diseased skin — an in vitro study on dendritic core–multishell nanotransporters. J Control Release 2014;185:45–50
   PubMed Web of Science ®Google Scholar
• Bolzinger M-A, Briançon S, Pelletier J, et al. Penetration of drugs through skin, a complex rate-controlling membrane. Curr Opin Colloid Interface Sci 2012;17:156–65
   Web of Science ®Google Scholar
• Lauterbach A, Müller-Goymann CC. Comparison of rheological properties, follicular penetration, drug release, and permeation behavior of a novel topical drug delivery system and a conventional cream. Eur J Pharm Biopharm 2014;88:614–24
   PubMed Web of Science ®Google Scholar
• Lauterbach A, Mueller-Goymann CC. Development, formulation, and characterization of an adapalene-loaded solid lipid microparticle dispersion for follicular penetration. Int J Pharm 2014;466:122–32
   PubMed Web of Science ®Google Scholar
• Ghanbarzadeh S, Arami S. Formulation and evaluation of piroxicam transferosomal gel: an approach for penetration enhancement. J Drug Deliv Sci Technol 2013;23:587–90
   Web of Science ®Google Scholar
• Doktorovova S, Souto EB, Silva AM. Nanotoxicology applied to solid lipid nanoparticles and nanostructured lipid carriers – a systematic review of in vitro data. Eur J Pharm Biopharm 2014;87:1–18
   PubMed Web of Science ®Google Scholar
• Weber S, Zimmer A, Pardeike J. Solid lipid nanoparticles (SLN) and nanostructured lipid carriers (NLC) for pulmonary application: a review of the state of the art. Eur J Pharm Biopharm 2014;86:7–22
   PubMed Web of Science ®Google Scholar
• Peng X-z, Zhong X-y, Yang H, et al. Comparison on influence of huangbai acne ointment prepared different techniques for structure of sebaceous glands of golden hamster. Guiding J Tradit Chin Med Pharm 2012;11:015
   Google Scholar
• Khan S, Baboota S, Ali J, et al. Chlorogenic acid stabilized nanostructured lipid carriers (NLC) of atorvastatin: formulation, design and in vivo evaluation. Drug Dev Ind Pharm 2015. [Epub ahead of print]. doi: 10.3109/03639045.2015.1040414
   Web of Science ®Google Scholar
• Niranjan K, Brian H, Harsh C. Physicochemical characterization techniques for solid lipid nanoparticles: principles and limitations. Drug Dev Ind Pharm 2014;40:1565–75
   PubMed Web of Science ®Google Scholar
• United States Pharmacopeia 35 – National Formulary 30. Flutamide capsul monograph. Rockville (MD): USP-NF; 2015
   Google Scholar
• Balakrishnan P, Shanmugam S, Lee WS, et al. Formulation and in vitro assessment of minoxidil niosomes for enhanced skin delivery. Int J Pharm 2009;377:1–8
   PubMed Web of Science ®Google Scholar
• Cevc G, Blume G. Hydrocortisone and dexamethasone in very deformable drug carriers have increased biological potency, prolonged effect, and reduced therapeutic dosage. Biochim Biophys Acta Biomembr 2004;1663:61–73
   PubMed Web of Science ®Google Scholar
• Elsayed MMA, Abdallah OY, Naggar VF, et al. Lipid vesicles for skin delivery of drugs: reviewing three decades of research. Int J Pharm 2007;332:1–16
   PubMed Web of Science ®Google Scholar
• Lombardi Borgia S, Regehly M, Sivaramakrishnan R, et al. Lipid nanoparticles for skin penetration enhancement – correlation to drug localization within the particle matrix as determined by fluorescence and parelectric spectroscopy. J Control Release 2005;110:151–63
   PubMed Web of Science ®Google Scholar
• Manosroi A, Chankhampan C, Manosroi W, et al. Transdermal absorption enhancement of papain loaded in elastic niosomes incorporated in gel for scar treatment. Eur J Pharm Sci 2013;48:474–83
   PubMed Web of Science ®Google Scholar
• Pinto MF, Moura CC, Nunes C, et al. A new topical formulation for psoriasis: development of methotrexate-loaded nanostructured lipid carriers. Int J Pharm 2014;477:519–26
   PubMed Web of Science ®Google Scholar
• Javadzadeh Y, Hamishehkar H. Enhancing percutaneous delivery of methotrexate using different types of surfactants. Colloids Surf B Biointerfaces 2011;82:422–6
   PubMed Web of Science ®Google Scholar
• Jain AK, Jain A, Garg NK, et al. Adapalene loaded solid lipid nanoparticles gel: an effective approach for acne treatment. Colloids Surf B Biointerfaces 2014;121:222–9
   PubMed Web of Science ®Google Scholar
• Küchler S, Radowski MR, Blaschke T, et al. Nanoparticles for skin penetration enhancement – a comparison of a dendritic core-multishell-nanotransporter and solid lipid nanoparticles. Eur J Pharm Biopharm 2009;71:243–50
   PubMed Web of Science ®Google Scholar
• Prow TW, Grice JE, Lin LL, et al. Nanoparticles and microparticles for skin drug delivery. Adv Drug Del Rev 2011;63:470–91
   PubMed Web of Science ®Google Scholar
• Schäfer-Korting M, Mehnert W, Korting H-C. Lipid nanoparticles for improved topical application of drugs for skin diseases. Adv Drug Deliv Rev 2007;59:427–43
   PubMed Web of Science ®Google Scholar
• Madheswaran T, Baskaran R, Thapa RK, et al. Design and in vitro evaluation of finasteride-loaded liquid crystalline nanoparticles for topical delivery. AAPS PharmSciTech 2013;14:45–52
   PubMed Web of Science ®Google Scholar
• Souto EB, Doktorovova S, Boonme P. Lipid-based colloidal systems (nanoparticles, microemulsions) for drug delivery to the skin: materials and end-product formulations. J Drug Deliv Sci Technol 2011;21:43–54
   Web of Science ®Google Scholar
• Pardeike J, Hommoss A, Müller RH. Lipid nanoparticles (SLN, NLC) in cosmetic and pharmaceutical dermal products. Int J Pharm 2009;366:170–84
   PubMed Web of Science ®Google Scholar
• Hamishehkar H, Shokri J, Fallahi S, et al. Histopathological evaluation of caffeine-loaded solid lipid nanoparticles in efficient treatment of cellulite. Drug Dev Ind Pharm 2014. [Epub ahead of print]. doi: 10.3109/03639045.2014.980426
   PubMed Web of Science ®Google Scholar
• Rasaee S, Ghanbarzadeh S, Mohammadi M, et al. Nano phytosomes of quercetin: a promising formulation for fortification of food products with antioxidants. Pharm Sci 2014;20:96–101
   Google Scholar
• Ghaderi S, Ghanbarzadeh S, Hamishehkar H. Evaluation of different methods to produce nanoparticle containing gammaoryzanol for potential use in food fortification. Pharm Sci 2015;20:130–4
   Google Scholar
• Trauer S, Richter H, Kuntsche J, et al. Influence of massage and occlusion on the ex vivo skin penetration of rigid liposomes and invasomes. Eur J Pharm Biopharm 2014;86:301–6
   PubMed Web of Science ®Google Scholar
• Lu GW, Warner KS, Wang F. Development of pilosebaceous unit-targeted drug products. In: Shah VP, Maibach HI, Jenner J, eds. Topical drug bioavailability, bioequivalence, and penetration. Berlin: Springer; 2014:181–215
   Google Scholar
• Pitaksuteepong T, Somsiri A, Waranuch N. Targeted transfollicular delivery of artocarpin extract from Artocarpus incisus by means of microparticles. Eur J Pharm Biopharm 2007;67:639–45
   PubMed Web of Science ®Google Scholar
• Subongkot T, Wonglertnirant N, Songprakhon P, et al. Visualization of ultradeformable liposomes penetration pathways and their skin interaction by confocal laser scanning microscopy. Int J Pharm 2013;441:151–61
   PubMed Web of Science ®Google Scholar
• Raphael AP, Meliga SC, Chen X, et al. Depth-resolved characterization of diffusion properties within and across minimally-perturbed skin layers. J Control Release 2013;166:87–94
   PubMed Web of Science ®Google Scholar
• Kovačević AB, Müller RH, Savić SD, et al. Solid lipid nanoparticles (SLN) stabilized with polyhydroxy surfactants: preparation, characterization and physical stability investigation. Colloids Surf Physicochem Eng Aspects 2014;444:15–25
   Web of Science ®Google Scholar
• Keck CM, Kovačević A, Müller RH, et al. Formulation of solid lipid nanoparticles (SLN): the value of different alkyl polyglucoside surfactants. Int J Pharm 2014;474:33–41
   PubMed Web of Science ®Google Scholar
• Kovacevic A, Savic S, Vuleta G, et al. Polyhydroxy surfactants for the formulation of lipid nanoparticles (SLN and NLC): effects on size, physical stability and particle matrix structure. Int J Pharm 2011;406:163–72
   PubMed Web of Science ®Google Scholar
• Mehnert W, Mäder K. Solid lipid nanoparticles: production, characterization and applications. Adv Drug Deliv Rev 2001;47:165–96
   PubMed Web of Science ®Google Scholar
• Zhai Y, Zhai G. Advances in lipid-based colloid systems as drug carrier for topic delivery. J Control Release 2014;193:90–9
   PubMed Web of Science ®Google Scholar
• Pople PV, Singh KK. Development and evaluation of colloidal modified nanolipid carrier: application to topical delivery of tacrolimus. Eur J Pharm Biopharm 2011;79:82–94
   PubMed Web of Science ®Google Scholar