References
- Sharom FJ. Multidrug resistance protein: P-glycoprotein. Drug Transporters. Hoboken (NJ): John Wiley & Sons, Inc.; 2006:223–62
- Gao X, Bhattacharya S, Chan WK, et al. Expression of P-glycoprotein and CYP3A4 along the porcine oral-gastrointestinal tract: implications on oral mucosal drug delivery. Drug Dev Ind Pharm 2014;40:599–603
- Ingwerson K. Cell cycle kinetics and antineoplastic agents. In: Barton-Burke M, Wilkes G, Ingwerson K, eds. Cancer chemotherapy: a nursing process approach. 3rd ed. Sudbury (MA): Jones and Bartlett Publishers, Inc.; 2001:42–4
- Seelig A. A general pattern for substrate recognition by P-glycoprotein. Eur J Biochem/FEBS 1998;251:252–61
- Ozben T. Mechanisms and strategies to overcome multiple drug resistance in cancer. FEBS Lett 2006;580:2903–9
- Varma MVS, Ashokraj Y, Dey CS, Panchagnula R. P-glycoprotein inhibitors and their screening: a perspective from bioavailability enhancement. Pharmacol Res 2003;48:347–59
- Föger F, Schmitz T, Bernkop-Schnürch A. In vivo evaluation of an oral delivery system for P-gp substrates based on thiolated chitosan. Biomaterials 2006;27:4250–5
- Werle M, Hoffer M. Glutathione and thiolated chitosan inhibit multidrug resistance P-glycoprotein activity in excised small intestine. J Control Release 2006;111:41–6
- Föger F, Kafedjiiski K, Hoyer H, et al. Enhanced transport of P-glycoprotein substrate saquinavir in presence of thiolated chitosan. J Drug Target 2007;15:132–9
- Liqin J, Xuemin L, Lingrong L, Qiqing Z. Thiolated chitosan-modified PLA-PCL-TPGS nanoparticles for oral chemotherapy of lung cancer. Nanoscale Res Lett 2013;8:66
- Kast CE, Bernkop-Schnürch A. Thiolated polymers – thiomers: development and in vitro evaluation of chitosan-thioglycolic acid conjugates. Biomaterials 2001;22:2345–52
- Brandt J, Svenson A, Carlsson J, Drevin H. Covalent coupling of unsaturated compounds to thiol agrarose using γ-radiation. J Solid-Phase Biochem 1977;2:105–9
- Wang X, Iqbal J, Rahmat D, Bernkop-Schnürch A. Preactivated thiomers: permeation enhancing properties. Int J Pharm 2012;438:217–24
- Iqbal J, Sarti F, Perera G, Bernkop-Schnürch A. Development and in vivo evaluation of an oral drug delivery system for paclitaxel. Biomaterials 2011;32:170–5
- Valentin P. Polymeric biomaterials: structure and function. 3rd ed. Boca Raton (FL): CRC Press; 2013
- Bernkop-Schnürch A, Schwarz V, Steininger S. Polymers with thiol groups: a new generation of mucoadhesive polymers? Pharm Res 1999;16:876–81
- Laffleur F, Hintzen F, Rahmat D, et al. Enzymatic degradation of thiolated chitosan. Drug Dev Ind Pharmacy. 2013;39:1531–9
- Saha P, Yang JJ, Lee VH. Existence of a p-glycoprotein drug efflux pump in cultured rabbit conjunctival epithelial cells. Invest Ophthalmol Vis Sci 1998;39:1221–6
- Profit L, Eagling VA, Back DJ. Modulation of P-glycoprotein function in human lymphocytes and Caco-2 cell monolayers by HIV-1 protease inhibitors. AIDS (London, England) 1999;13:1623–7
- Gradauer K, Dünnhaupt S, Vonach C, et al. Thiomer-coated liposomes harbor permeation enhancing and efflux pump inhibitory properties. J Control Release: Offic J Control Release Soc 2013;165:207–15
- Junginger HE. Polymeric permeation enhancers. In: Bernkop-Schnürch A, ed. Oral delivery of macromolecular drugs: barriers, strategies and future trends. New York: Springer Science & Business Media; 2009
- Greindl M, Föger F, Hombach J, Bernkop-Schnürch A. In vivo evaluation of thiolated poly(acrylic acid) as a drug absorption modulator for MRP2 efflux pump substrates. Eur J Pharm Biopharm 2009;72:561–6
- Palmberger TF, Hombach J, Bernkop-Schnürch A. Thiolated chitosan: development and in vitro evaluation of an oral delivery system for acyclovir. Int J Pharm 2008;348:54–60
- Loo TW, Bartlett MC, Clarke DM. Transmembrane segment 1 of human P-glycoprotein contributes to the drug-binding pocket. Biochem J 2006;396:537–45
- Bernkop-Schnürch A, Grabovac V. Polymeric efflux pump inhibitors in oral drug delivery. Am J Drug Deliv 2006;4:263–72
- Bernkop-Schnürch A, Krauland AH, Leitner VM, Palmberger T. Thiomers: potential excipients for non-invasive peptide delivery systems. Eur J Pharmaceut Biopharmaceut 2004;58:253–63
- Dassa E, Bouige P. The ABC of ABCs: a phylogenetic and functional classification of ABC systems in living organisms. Res Microbiol 2001;152:211–29
- Dean M, Rzhetsky A, Allikmets R. The human ATP-binding cassette (ABC) transporter superfamily. Genome Res 2001;11:1156–66
- Sharom FJ. ABC multidrug transporters: structure, function and role in chemoresistance. Pharmacogenomics 2008;9:105–27