References
- Murthy SN, Maibach HI. Topical nail products and ungual drug delivery. Boca Raton: Taylor & Francis/CRC Press; 2013.
- Barot BS, Parejiya PB, Patel HK, et al. Drug delivery to the nail: therapeutic options and challenges for onychomycosis. Crit Rev Ther Drug Carrier Syst 2014;31:459–94.
- Elkeeb R, Hui X, Murthy N, Maibach HI. Emerging topical onychomycosis therapies - quo vadis? Expert Opin Emerg Drugs 2014;19:489–95.
- Kushwaha A, Murthy RN, Murthy SN, et al. Emerging therapies for the treatment of ungual onychomycosis. Drug Dev Ind Pharm 2015;22:1–7.
- Shivakumar HN, Juluri A, Desai BG, Murthy SN. Ungual and transungual drug delivery. Drug Dev Ind Pharm 2012;38:901–11.
- Murdan S. Drug delivery to the nail following topical application. Int J Pharm 2002;236:1–26.
- Gupta AK, Simpson F. Device-based therapies for onychomycosis treatment. Skin Therapy Lett 2012;17:4–9.
- Kobayashi Y, Miyamoto M, Sugibayashi K, Morimoto Y. Drug permeation through the three layers of the human nail plate. J Pharm Pharmacol 1999;51:271–8.
- Lewis BL. Microscopic studies of fetal and mature nail and surrounding soft tissue. AMA Arch Derm Syphilol 1954;70:733–47.
- Mertin D, Lippold BC. In-vitro permeability of the human nail and of a keratin membrane from bovine hooves: prediction of the penetration rate of antimycotics through the nail plate and their efficacy. J Pharm Pharmacol 1997;49:866–72.
- Saner MV, Kulkarni AD, Pardeshi CV. Insights into drug delivery across the nail plate barrier. J Drug Target 2014;22:769–89.
- Kushwaha A, Jacob M, Shiva Kumar HN, et al. Trans-ungual delivery of itraconazole hydrochloride by iontophoresis. Drug Dev Ind Pharm 2014;8:1–5.
- Manda P, Sammeta SM, Repka MA, Murthy SN. Iontophoresis across the proximal nail fold to target drugs to the nail matrix. J Pharm Sci 2012;101:2392–7.
- Palliyil BB, Li C, Owaisat S, Lebo DB. Lateral drug diffusion in human nails. AAPS Pharm Sci Tech 2014;15:1429–38.
- Murthy SN, Waddell DC, Shivakumar HN, et al. Iontophoretic permselective property of human nail. J Dermatol Sci 2007;46:150–2.
- Nair AB, Kim HD, Chakraborty B, et al. Ungual and trans-ungual iontophoretic delivery of terbinafine for the treatment of onychomycosis. J Pharm Sci 2009;98:4130–40.
- Nair AB, Vaka SR, Sammeta SM, et al. Trans-ungual iontophoretic delivery of terbinafine. J Pharm Sci 2009;98:1788–96.
- Nair AB, Kim HD, Davis SP, et al. An ex vivo toe model used to assess applicators for the iontophoretic ungual delivery of terbinafine. Pharm Res 2009;26:2194–201.
- Nair AB, Vaka SR, Murthy SN. Transungual delivery of terbinafine by iontophoresis in onychomycotic nails. Drug Dev Ind Pharm 2011;37:1253–8.
- Murthy SN. Iontophoresis for treating nail diseases. Ther Deliv 2013;4:647–50.
- Dutet J, Delgado-Charro MB. Assessment of iontophoretic and passive ungual penetration by laser scanning confocal microscopy. Pharm Res 2012;29:3464–74.
- Sachdeva V, Kim HD, Friden PM, Banga AK. Iontophoresis mediated in vivo intradermal delivery of terbinafine hydrochloride. Int J Pharm 2010;393:113–19.
- Hao J, Smith KA, Li SK. Iontophoretically enhanced ciclopirox delivery into and across human nail plate. J Pharm Sci 2009;98:3608–16.
- Manda P, Murthy SN. Iontophoretic drug delivery for the treatment of scars. J Pharm Sci 2014;103:1638–42.
- Amichai B, Mosckovitz R, Trau H, et al. Iontophoretic terbinafine HCL 1.0% delivery across porcine and human nails. Mycopathologia 2010;169:343–9.
- Nair AB, Singh K, Shinu P, et al. A comprehensive study to evaluate the effect of constant low voltage iontophoresis on transungual delivery. Drug Dev Ind Pharm 2013;39:807–15.
- Yeganeh MH, McLachlan AJ. Determination of terbinafine in tissues. Biomed. Chromatogr 2000;14:261–8.
- Dykes PJ, Thomas R, Finlay AY. Determination of terbinafine in nail samples during systemic treatment for onychomycoses. Br J Dermatol 1990;123:481–6.
- Chen Y, Wang Y, Zhu M, et al. HPLC determination of fluorescein sodium injection and its related substances. Chin J Pharm Anal 2008;28:961–3.
- Shivakumar HN, Vaka SR, Madhav NV, et al. Bilayered nail lacquer of terbinafine hydrochloride for treatment of onychomycosis. J Pharm Sci 2010;99:4267–76.
- Nair AB, Sammeta SM, Kim HD, et al. Alteration of the diffusional barrier property of the nail leads to greater terbinafine drug loading and permeation. Int J Pharm 2009;375:22–7.
- Nair AB, Chakraborty B, Murthy SN. Effect of polyethylene glycols on the trans-ungual delivery of terbinafine. Curr Drug Deliv 2010;7:407–14.
- Myoung Y, Choi HK. Permeation of ciclopirox across porcine hoof membrane: effect of pressure sensitive adhesives and vehicles. Eur J Pharm Sci 2003;20:319–25.
- Hafeez F, Hui X, Selner M, et al. Ciclopirox delivery into the human nail plate using novel lipid diffusion enhancers. Drug Dev Ind Pharm 2014;40:838–44.
- Chouhan P, Saini TR. Hydration of nail plate: a novel screening model for transungual drug permeation enhancers. Int J Pharm 2012;436:179–82.
- Tanrıverdi ST1, Özer Ö. Novel topical formulations of Terbinafine-HCl for treatment of onychomycosis. Eur J Pharm Sci 2013;48:628–36.