Hyperoside nanocrystals for HBV treatment: process optimization, in vitro and in vivo evaluation

References

• Zou Y, Lu Y, Wei D. Antioxidant activity of a flavonoid-rich extract of Hypericum perforatum L. in vitro. J Agric Food Chem 2004;52:5032–9.
   PubMed Web of Science ®Google Scholar
• Wang XR, Zhou ZH, Du AQ, Huang ZM. Studies on the flavonol constituents of Abelmoschus manihot L. Medic Chin J Nat Med 2004;2:91–3.
   Google Scholar
• Jurikova T, Sochor J, Rop O, et al. Polyphenolic profile and biological activity of Chinese hawthorn (Crataegus pinnatifida BUNGE) fruits. Molecules 2012;17:14490–509.
   PubMed Web of Science ®Google Scholar
• Li J, Huang H, Zhou W, et al. Anti-hepatitis B virus activities of Geranium carolinianum L. extracts and identification of the active components. Biol Pharm Bull 2008;31:743–7.
   PubMed Web of Science ®Google Scholar
• Feng X, Li YH, Liang CY, et al. Chemical constituents from Embelia laeta. Zhong Yao Cai 2013;36:1947–9.
   PubMedGoogle Scholar
• Wu LL, Yang XB, Huang ZM, et al. In vivo and in vitro antiviral activity of hyperoside extracted from Abelmoschus manihot (L) medic. Acta Pharmacol Sin 2007;28:404–9.
   PubMed Web of Science ®Google Scholar
• Ku SK, Kwak S, Kwon OJ, Bae JS. Hyperoside inhibits high-glucose-induced vascular inflammation in vitro and in vivo. Inflammation 2014;37:1389–400.
   PubMed Web of Science ®Google Scholar
• Choi JH, Kim DW, Yun N, et al. Protective effects of hyperoside against carbon tetrachloride-induced liver damage in mice. J Nat Prod 2011;74:1055–60.
   PubMed Web of Science ®Google Scholar
• Cao XS, Sha M, Ou YQ, et al. In vivo integrated pharmacokinetics of four flavonoids of Abelmoschus manihot extract in rats. Zhong Cao Yao 2010;41:255–9.
   Google Scholar
• Zhong H, Zhu Y, Yu JN, Xu XM. Advanced in solubilization methods of water-insoluble natural drugs. Zhongguo Zhong Yao Za Zhi 2014;39:3226–31.
   PubMedGoogle Scholar
• He S, Yang H, Zhang R, et al. Preparation and in vitro-in vivo evaluation of teniposide nanosuspensions. Int J Pharm 2014;478:131–7.
   PubMed Web of Science ®Google Scholar
• Mishra B, Sahoo J, Dixit PK. Formulation and process optimization of naproxen nanosuspensions stabilized by hydroxy propyl methyl cellulose. Carbohydr Polym 2015;127:300–8.
   PubMed Web of Science ®Google Scholar
• Scholz P, Keck CM. Flavonoid nanocrystals produced by ARTcrystal®-technology. Int J Pharm 2015;482:27–37.
   PubMed Web of Science ®Google Scholar
• Keck CM, Müller RH. Drug nanocrystals of poorly soluble drugs produced by high pressure homogenization. Eur J Pharm Biopharm 2006;62:3–16.
   PubMed Web of Science ®Google Scholar
• Ahuja BK, Jena SK, Paidi SK, et al. Formulation, optimization and in vitro-in vivo evaluation of febuxostat nanosuspension. Int J Pharm 2015;478:540–52.
   PubMed Web of Science ®Google Scholar
• Shegokar R, Müller RH. Nanocrystals: industrially feasible multifunctional formulation technology for poorly soluble actives. Int J Pharm 2010;399:129–39.
   PubMed Web of Science ®Google Scholar
• Möschwitzer JP. Drug nanocrystals in the commercial pharmaceutical development process. Int J Pharm 2013;453:142–56.
   PubMed Web of Science ®Google Scholar
• Guo JJ, Yue PF, Lv JL, et al. Development and in vivo/in vitro evaluation of novel herpetrione nanosuspension. Int J Pharm 2013;441:227–33.
   PubMed Web of Science ®Google Scholar
• Yue PF, Li Y, Wan J, et al. Process optimization and evaluation of novel baicalin solid nanocrystals. Int J Nanomedicine 2013;8:2961–73.
   PubMed Web of Science ®Google Scholar
• Sun M, Gao Y, Pei Y, et al. Development of nanosuspension formulation for oral delivery of quercetin. J Biomed Nanotechnol 2010;6:325–32.
   PubMed Web of Science ®Google Scholar
• Ai G, Huang ZM, Wang DW, et al. Pharmacokinetics study of hyperoside in rats. Chin J Exp Trad Med Form 2013;19:158–61.
   Google Scholar
• Wu N, Zhang LH, Cheng L, et al. Preparation of hyperoside solid nanocrystal and evaluation of its in vitro release. Zhong Cao Yao 2015;46:1759–63.
   Google Scholar
• Cui J, Li C, Deng Y, et al. Freeze-drying of liposomes using tertiary butyl alcohol/water cosolvent systems. Int J Pharm 2006;312:131–6.
   PubMed Web of Science ®Google Scholar
• Zelenková T, Barresi AA, Fissore D. On the use of tert-butanol/water cosolvent systems in production and freeze-drying of poly-ɛ-caprolactone nanoparticles. J Pharm Sci 2015;104:178–90.
   PubMed Web of Science ®Google Scholar
• Han YQ, Huang ZM, Yang XB, et al. In vivo and in vitro anti-hepatitis B virus activity of total phenolics from Oenanthe javanica. J Ethnopharmacol 2008;118:148–53.
   PubMed Web of Science ®Google Scholar
• Xu Y, Liu X, Lian R, et al. Enhanced dissolution and oral bioavailability of aripiprazole nanosuspensions prepared by nanoprecipitation/homogenization based on acid-base neutralization. Int J Pharm 2012;438:287–95.
   PubMed Web of Science ®Google Scholar
• Ghosh I, Schenck D, Bose S, Ruegger C. Optimization of formulation and process parameters for the production of nanosuspension by wet media milling technique: effect of Vitamin E TPGS and nanocrystal particle size on oral absorption. Eur J Pharm Sci 2012;47:718–28.
   PubMed Web of Science ®Google Scholar
• Wang Y, Zheng Y, Zhang L, et al. Stability of nanosuspensions in drug delivery. J Control Release 2013;72:1126–41.
   Web of Science ®Google Scholar
• Yue PF, Li Y, Wan J, et al. Study on formability of solid nanosuspensions during nanodispersion and solidification: I. Novel role of stabilizer/drug property. Int J Pharm 2013;454:269–77.
   PubMed Web of Science ®Google Scholar
• Xia D, Cui F, Piao H, et al. Effect of crystal size on the in vitro dissolution and oral absorption of nitrendipine in rats. Pharm Res 2010;27:1965–76.
   PubMed Web of Science ®Google Scholar
• Junghanns JU, Müller RH. Nanocrystal technology, drug delivery and clinical applications. Int J Nanomedicine 2008;3:295–309.
   PubMed Web of Science ®Google Scholar
• Erlund I, Kosonen T, Alfthan G, et al. Pharmacokinetics of quercetin from quercetin aglycone and rutin in healthy volunteers. Eur J Clin Pharmacol 2000;56:545–53.
   PubMed Web of Science ®Google Scholar
• Godfrey KR, Arundel PA, Dong Z, Bryant R. Modelling the double peak phenomenon in pharmacokinetics. Comput Methods Programs Biomed 2011;104:62–9.
   PubMed Web of Science ®Google Scholar
• Lu L, Qian D, Guo J, et al. Abelmoschi corolla non-flavonoid components altered the pharmacokinetic profile of its flavonoids in rat. J Ethnopharmacol 2013;148:804–11.
   PubMed Web of Science ®Google Scholar
• Ying X, Meng X, Wang S, et al. Simultaneous determination of three polyphenols in rat plasma after orally administering hawthorn leaves extract by the HPLC method. Nat Prod Res 2012;26:585–91.
   PubMed Web of Science ®Google Scholar
• Xia D, Quan P, Piao H, et al. Preparation of stable nitrendipine nanosuspensions using the precipitation-ultrasonication method for enhancement of dissolution and oral bioavailability. Eur J Pharm Sci 2010;40:325–34.
   PubMed Web of Science ®Google Scholar
• Geng M, Wang JH, Chen HY, et al. Effects of hyperin on the cccDNA of duck hepatitis B virus and its immunological regulation. Yao Xue Xue Bao 2009;44:1440–4.
   PubMedGoogle Scholar