Drug Development and Industrial Pharmacy, Volume 42, Issue 11 (2016)

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Drug Development and Industrial Pharmacy, Volume 42, Issue 11 (2016)

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Research Articles

Article
Synchronous delivery of felodipine and metoprolol tartrate using monolithic osmotic pump technology
Shiqing Zhao, Fanglin Yu, Nan Liu, Zhong Di, Kun Yan, Yan Liu, Ying Li, Hui Zhang, Yang Yang, Zhenbo Yang, Zhiping Li & Xingguo Mei
Pages: 1723-1731
Published online: 13 Apr 2016
AbstractforSynchronous delivery of felodipine and metoprolol tartrate using monolithic osmotic pump technology | Full Text | References | PDF (1.5 MB)
  • 218 Views
  • 7 CrossRef citations
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Article
Studies on the in vitro and in vivo degradation behavior of amino acid derivative-based organogels
Zhen Li, Jinxu Cao, Beibei Hu, Heran Li, Hongzhuo Liu, Fei Han, Zhenyun Liu, Chao Tong & Sanming Li
Pages: 1732-1741
Published online: 19 Apr 2016
AbstractforStudies on the in vitro and in vivo degradation behavior of amino acid derivative-based organogels | Full Text | References | PDF (1.5 MB)
  • 201 Views
  • 11 CrossRef citations
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Article
In vitro models to estimate drug penetration through the compromised stratum corneum barrier
André Engesland, Nataša Škalko-Basnet & Gøril Eide Flaten
Pages: 1742-1751
Published online: 13 Apr 2016
AbstractforIn vitro models to estimate drug penetration through the compromised stratum corneum barrier | Full Text | References | PDF (1.2 MB) | Supplemental
  • 456 Views
  • 13 CrossRef citations
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Article
Nanoparticles as tool for enhanced ophthalmic delivery of vancomycin: a multidistrict-based microbiological study, solid lipid nanoparticles formulation and evaluation
Carol Yousry, Rania Hassan Fahmy, Tamer Essam, Hanan M. El-laithy & Seham A. Elkheshen
Pages: 1752-1762
Published online: 19 Apr 2016
AbstractforNanoparticles as tool for enhanced ophthalmic delivery of vancomycin: a multidistrict-based microbiological study, solid lipid nanoparticles formulation and evaluation | Full Text | References | PDF (1.6 MB)
  • 331 Views
  • 32 CrossRef citations
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Article
Development and gamma-scintigraphy study of Hibiscus rosasinensis polysaccharide-based microspheres for nasal drug delivery
Nitin Sharma, Shanu Tyagi, Satish Kumar Gupta, Giriraj Thirupathirao Kulkarni, Aseem Bhatnagar & Neeraj Kumar
Pages: 1763-1771
Published online: 19 Apr 2016
AbstractforDevelopment and gamma-scintigraphy study of Hibiscus rosasinensis polysaccharide-based microspheres for nasal drug delivery | Full Text | References | PDF (1.5 MB)
  • 130 Views
  • 5 CrossRef citations
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Article
Hyperoside nanocrystals for HBV treatment: process optimization, in vitro and in vivo evaluation
Baode Shen, Na Wu, Chengying Shen, Fucheng Zhang, Yan Wu, Pinghua Xu, Lihong Zhang, Wei Wu, Yi Lu, Jin Han, Yonggang Wang & Hailong Yuan
Pages: 1772-1781
Published online: 24 Apr 2016
AbstractforHyperoside nanocrystals for HBV treatment: process optimization, in vitro and in vivo evaluation | Full Text | References | PDF (3.1 MB)
  • 232 Views
  • 21 CrossRef citations
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Article
Novel gold nanoparticles coated with somatostatin as a potential delivery system for targeting somatostatin receptors
Ahmed A. H. Abdellatif, Gamal Zayed, Asmaa El-Bakry, Alaa Zaky, Imran Y. Saleem & Hesham M. Tawfeek
Pages: 1782-1791
Published online: 05 May 2016
AbstractforNovel gold nanoparticles coated with somatostatin as a potential delivery system for targeting somatostatin receptors | Full Text | References | PDF (1.7 MB) | Supplemental
  • 243 Views
  • 40 CrossRef citations
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Article
Pharmacokinetics and tissue distribution of two novel isomerism anticancer platinum compounds
Donglin He, Shuhui Yin, Fuguo Han, Jingjie Zhu, Yun Shi, Zhiyuan Tong & Qingfei Liu
Pages: 1792-1799
Published online: 24 Apr 2016
AbstractforPharmacokinetics and tissue distribution of two novel isomerism anticancer platinum compounds | Full Text | References | PDF (920.3 KB)
  • 126 Views
  • 4 CrossRef citations
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Article
The improved dissolution performance of a post processing treated spray-dried crystalline solid dispersion of poorly soluble drugs
Siok-Yee Chan, Seok-Ming Toh, Nasir Hayat Khan, Yin-Ying Chung & Xin-Zi Cheah
Pages: 1800-1812
Published online: 24 Apr 2016
AbstractforThe improved dissolution performance of a post processing treated spray-dried crystalline solid dispersion of poorly soluble drugs | Full Text | References | PDF (3.2 MB) | Supplemental
  • 200 Views
  • 6 CrossRef citations
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Article
Spray-dried solid dispersions containing ferulic acid: comparative analysis of three carriers, in vitro dissolution, antioxidant potential and in vivo anti-platelet effect
Jessica Mendes Nadal, Mona Lisa Simionatto Gomes, Débora Maria Borsato, Martinha Antunes Almeida, Fernanda Malaquias Barboza, Sônia Faria Zawadzki, Paulo Vitor Farago & Sandra Maria Warumby Zanin
Pages: 1813-1824
Published online: 24 Apr 2016
AbstractforSpray-dried solid dispersions containing ferulic acid: comparative analysis of three carriers, in vitro dissolution, antioxidant potential and in vivo anti-platelet effect | Full Text | References | PDF (1.8 MB)
  • 234 Views
  • 20 CrossRef citations
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Article
On-line monitoring of vacuum drying of theophylline using NIR spectroscopy: solid-state transitions, water content and semi-empirical modeling
Touil Amira, Peczalski Roman & Zagrouba Fethi
Pages: 1825-1832
Published online: 30 May 2016
AbstractforOn-line monitoring of vacuum drying of theophylline using NIR spectroscopy: solid-state transitions, water content and semi-empirical modeling | Full Text | References | PDF (1.4 MB)
  • 128 Views
  • 2 CrossRef citations
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Article
Optimization of hot melt extrusion parameters for sphericity and hardness of polymeric face-cut pellets
Abdullah S. Alshetaili, Bjad K. Almutairy, Saad M. Alshahrani, Eman A. Ashour, Roshan V. Tiwari, Sultan M. Alshehri, Xin Feng, Bader B. Alsulays, Soumyajit Majumdar, Nigel Langley, Karl Kolter, Andreas Gryczke, Scott T. Martin & Michael A. Repka
Pages: 1833-1841
Published online: 04 May 2016
AbstractforOptimization of hot melt extrusion parameters for sphericity and hardness of polymeric face-cut pellets | Full Text | References | PDF (3 MB)
  • 317 Views
  • 18 CrossRef citations
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Article
Influence of spray drying and dispersing agent on surface and dissolution properties of griseofulvin micro and nanocrystals
Dhaval A. Shah, Manan Patel, Sharad B. Murdande & Rutesh H. Dave
Pages: 1842-1850
Published online: 04 May 2016
AbstractforInfluence of spray drying and dispersing agent on surface and dissolution properties of griseofulvin micro and nanocrystals | Full Text | References | PDF (1.8 MB)
  • 329 Views
  • 15 CrossRef citations
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Article
Characterization of melt-quenched and milled amorphous solids of gatifloxacin
Yusuke Hattori, Ayumi Suzuki & Makoto Otsuka
Pages: 1851-1856
Published online: 22 May 2016
AbstractforCharacterization of melt-quenched and milled amorphous solids of gatifloxacin | Full Text | References | PDF (1.3 MB) | Supplemental
  • 189 Views
  • 4 CrossRef citations
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Article
Processing-induced-transformations (PITs) during direct compression: impact of compression speeds on phase transition of caffeine
Audrey Juban, Stephanie Briancon & François Puel
Pages: 1857-1864
Published online: 10 May 2016
AbstractforProcessing-induced-transformations (PITs) during direct compression: impact of compression speeds on phase transition of caffeine | Full Text | References | PDF (1,003.8 KB)
  • 209 Views
  • 6 CrossRef citations
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Article
Lysozyme-loaded lipid-polymer hybrid nanoparticles: preparation, characterization and colloidal stability evaluation
Burcu Devrim, Aslı Kara, İmran Vural & Asuman Bozkır
Pages: 1865-1876
Published online: 28 Apr 2016
AbstractforLysozyme-loaded lipid-polymer hybrid nanoparticles: preparation, characterization and colloidal stability evaluation | Full Text | References | PDF (2.1 MB)
  • 781 Views
  • 37 CrossRef citations
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Article
Flow and compaction properties of hypromellose: new directly compressible versus the established grades
Peter Grdešič, Franc Vrečer & Ilija Ilić
Pages: 1877-1886
Published online: 13 May 2016
AbstractforFlow and compaction properties of hypromellose: new directly compressible versus the established grades | Full Text | References | PDF (1.8 MB)
  • 402 Views
  • 14 CrossRef citations
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Article
Spray-dried high-amylose sodium carboxymethyl starch: impact of α-amylase on drug-release profile
Teresa Nabais, Sarra Zaraa & Grégoire Leclair
Pages: 1887-1893
Published online: 10 May 2016
AbstractforSpray-dried high-amylose sodium carboxymethyl starch: impact of α-amylase on drug-release profile | Full Text | References | PDF (1,019.7 KB)
  • 155 Views
  • 2 CrossRef citations
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Article
Application of design of experiments for formulation development and mechanistic evaluation of iontophoretic tacrine hydrochloride delivery
Niketkumar Patel, Shashank Jain, Parshotam Madan & Senshang Lin
Pages: 1894-1902
Published online: 10 May 2016
AbstractforApplication of design of experiments for formulation development and mechanistic evaluation of iontophoretic tacrine hydrochloride delivery | Full Text | References | PDF (1.1 MB)
  • 131 Views
  • 9 CrossRef citations
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Article
Use of к-carrageenan, chitosan and Carbopol 974P in extruded and spheronized pellets that are devoid of MCC
Brenda L. Valle, Wycliffe S. Omwancha, Steven H. Neau & Rodney J. Wigent
Pages: 1903-1916
Published online: 10 May 2016
AbstractforUse of к-carrageenan, chitosan and Carbopol 974P in extruded and spheronized pellets that are devoid of MCC | Full Text | References | PDF (2.1 MB)
  • 146 Views
  • 2 CrossRef citations
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