Aging of Natural and Acquired Immunity of Mice. II. Decreased T Cell Responses to Syngeneic Tumor Cells and Parental-Strain Spleen Cells

References

• Albright J W, Makinodan T. Decline in the growth potential of spleen-colonizing bone marrow stem cells of long-lived aging mice. J Exp Med 1976; 144: 1204–1213
   PubMed Web of Science ®Google Scholar
• Burnet M. An immunological approach to aging. Lancet 1970; 2: 358
   PubMed Web of Science ®Google Scholar
• Lewis V M, Twomey I, Bealmear P, Goldstein G, Good R. Age, thymic involution and circulating thymic hormone activity. J Clin Endocrinol Metab 1978; 47: 145–150
   PubMed Web of Science ®Google Scholar
• Callard R E, Basten A. Immune function in aged mice. I. T-cell responsiveness using phytohemagglutinin as a functional probe. Cell Immunol 1977; 31: 13–25
   PubMed Web of Science ®Google Scholar
• Kay M B, Mendoza J, Diven J, Denton T, Union N, Lajiness M. Age-related changes in the immune system of mice of eight medium and long-lived strains and hybrids. I. Organ, cellular and activity changes. Mech Aging Dev 1979; 11: 295–315
   PubMed Web of Science ®Google Scholar
• Callard R E, De Groth B F, St, Basten A, McKenzie I F C. Immune function in aged mice. V. Role of suppressor cells. J Immunol 1980; 124: 51–53
   Google Scholar
• Weksler M E, Innes J B, Goldstein G. Immunological studies of aging. IV. The contribution of thymic involution to the immune deficiencies of aging mice and reversal with thymopoietin. J Exp Med 1978; 148: 996–1006
   PubMed Web of Science ®Google Scholar
• Hirokawa K, Makinodan T. Thymic involution: effect on T cell differentiation. J Immunol 1975; 114: 1659–1664
   PubMed Web of Science ®Google Scholar
• Meredith P, Titton W, Gerbase-Delima M, Walford R. Age-related changes in the cellular immune response of lymph node and thymus cells in long lived mice. Cell Immunol 1975; 18: 324–330
   PubMed Web of Science ®Google Scholar
• Gerbase-DeLima M, Wilkinson J, Smith G S, Walford R L. Age-related decline in thymic-independent immune function in a long-lived mouse strain. J Gerontol 1974; 29: 261–270
   PubMedGoogle Scholar
• Friedman D, Keiser V, Globerson A. Reactivation of immunocompetence in spleen cells of aged mice. Nature (London) 1974; 251: 545–546
   PubMed Web of Science ®Google Scholar
• Goodman S A, Makinodan T. Effect of Age on cell-mediated immunity in long-lived mice. Clin Exp Immunol 1975; 19: 533–542
   PubMed Web of Science ®Google Scholar
• Hirano T, Nordin A. Age associated decline in the in-vitro development of cytotoxic lymphocytes in NZB mice. J Immunol 1976; 117: 1093–1098
   PubMed Web of Science ®Google Scholar
• Krohn P L. Review lectures on senescence. II. Heterochronic transplantation in the study of aging. Proc R Soc London, Ser. 1963; 157: 128
   Web of Science ®Google Scholar
• Shigemoto S, Kishimoto S, Yamamura Y. Change of cell-mediated cytotoxicity with aging. J Immunol 1975; 115: 307–309
   PubMed Web of Science ®Google Scholar
• Stutman O. Cell-mediated immunity and aging. Fed Proc 1974; 33: 2028–2032
   PubMedGoogle Scholar
• Stutman O, Yunis E J, Good R A. Studies on thymus function. III. Duration of thymic function. J Exp Med 1972; 135: 339–356
   PubMed Web of Science ®Google Scholar
• Bennett M. Effect of age on immune function in terms of chemically induced cancers. Environ Health Perspec 1979; 29: 17–22
   PubMed Web of Science ®Google Scholar
• Smith R T, Landy M. Immune Surveillance. Academic Press, New York 1970
   Google Scholar
• Walford R L. The Immunologic Theory of Aging. Einer Munskgaard, Copenhagen 1969
   Google Scholar
• Stutman O. Tumor development after 3-methylcholanthrene in immunologically deficient athymic nude mice. Science 1974; 183: 534–536
   PubMed Web of Science ®Google Scholar
• Fitzgerald P A, Bennett M. Aging of natural and acquired immunity of mice. I. Decreased natural killer cell function and hybrid resistance to marrow cell grafts. Cancer Invest 1983; 1: 15–24
   PubMed Web of Science ®Google Scholar
• Bennett M, Baker E E, Eastcott J W, Kumar V, Yonkosky D. Selective elimination of marrow precursors with the bone seeking isotope 89Sr; implications for hemopoiesis, lymphopoiesis, viral leukemogenesis and infection. J Reticuloendothel Soc 1975; 20: 71–76
   Google Scholar
• Seaman W E, Blackman M A, Gendhert T D, Roubinian J R, Loeb J, Talal N. β-Estradiol reduces natural killer cells in mice. J Immunol 1978; 121: 2193–2198
   PubMed Web of Science ®Google Scholar
• Seaman W E, Gundhart T D, Greenspan J S, Blackman M A, Talal N. 1979 Natural killer cells, bone and the bone marrow: studies in estrogen-treated mice and in con-genitally osteopetrotic (mi/mi) mice. J Immunol, 122: 2541–2547
   PubMed Web of Science ®Google Scholar
• Seaman W E, Merigan T C, Talal N. Natural killing in estrogen-treated mice responds poorly to Poly I:C despite normal stimulation of circulating interferon. J Immunol 1979; 123: 2903–2905
   PubMed Web of Science ®Google Scholar
• Mantel N. Evaluation of survival data and two new rank order statistics arising in its consideration. Cancer Chemother Rep 1966; 50: 163–170
   PubMedGoogle Scholar
• Miller R G, Phillips R A. Reduction of the in vitro cytotoxic lymphocyte response produced by in vivo exposure to semiallogeneic cells: Recruitment or active suppression. J Immunol 1976; 117: 1913–1921
   PubMed Web of Science ®Google Scholar
• Takei F, Levy J G, Kilburn D G. In vitro induction of cytotoxicity against syngeneic mastocytoma and its suppression by spleen and thymus cells from tumor-bearing mice. J Immunol 1976; 116: 288–293
   PubMed Web of Science ®Google Scholar
• Takei F, Levy J, Kilburn D. Characterization of a soluble factor that specifically suppresses the in vitro generation of cells cytotoxic for syngeneic tumor cells in mice. J Immunol 1978; 120: 1218–1224
   PubMed Web of Science ®Google Scholar
• Fujimoto S, Matsuzawa T, Nakagawa K, Tada T. Cellular interaction between cytotoxic and suppressor T cells against syngeneic tumors in the mouse. Cell Immunol 1978; 38: 378–387
   PubMed Web of Science ®Google Scholar
• Kumar V, Caruso T, Bennett M. Mechanisms of genetic resistance to Friend virus leukemia. III. Susceptibility of mitogen-responsive lymphocytes mediated by T cells. J Exp Med 1976; 143: 728–740
   PubMed Web of Science ®Google Scholar
• Levy E M, Bennett M, Kumar V, Fitzgerald P, Cooperband S R. Adoptive transfer of spleen cells from mice treated with radioactive strontium: suppressor cells, natural killer cells, and “hybrid resistance” in recipient mice. J Immunol 1980; 124: 611–618
   PubMed Web of Science ®Google Scholar
• Merluzzi V J, Levy E M, Kumar V, Bennett M, Cooperband S R. In vitro activation of suppressor cells from spleens of mice treated with radioactive strontium. J Immunol 1978; 121: 505–512
   PubMed Web of Science ®Google Scholar
• Leuvano E, Kumar V, Bennett M. Hybrid resistance to EL-4 lymphoma cells. II. Association between loss of hybrid resistance with detection of suppressor cells after treatment of mice with 89Sr. Scand J Immunol 1981; 13: 563–571
   PubMed Web of Science ®Google Scholar
• Kumar V, Luevano E, Bennett M. Hybrid resistance to EL-4 lymphoma cells. I. Characterization of natural killer cells which lyse EL-4 cells and their distinction from marrow-dependent natural killer cells. J Exp Med 1979; 150: 531–547
   PubMed Web of Science ®Google Scholar
• Bennett M, Melvold R W, Kohn H E. Bone marrow cell grafts involving the H-2D and H-2L mutant haplotypes. Immunogenetics 1980; 10: 273–2; 1
   Web of Science ®Google Scholar
• Eastcott J W, Broitman S A, Bennett M. Immunogenetic differences between lymph cell and bone marrow cell grafts in irradiated mice. Cell Immunol 1981; 58: 124–133
   PubMedGoogle Scholar
• Nakamura I, Nakano K, Cudkowicz G. Fl hybrid antiparent H-2d cytotoxicity: genetic control by H-2D and H-2L genes. In XIIIth International Leukocyte Culture Conference (National Research Council of Canada). 1979
   Google Scholar