Tumor Suppressor Genes and Cancer of the Human Nervous System

References

• Harris J, Miller O J, Klein G, et al. Suppression of malignancy by cell fusion. Nature 1969; 223: 363–368
   PubMed Web of Science ®Google Scholar
• Klein G, Bregula U, Weiner F, et al. The analysis of malignancy by cell fusion. I. Hybrids between tumour cells and L cell derivatives. J Cell Sci 1974; 8: 659–672
   Google Scholar
• Stanbridge EJ. Genetic regulation of tumorigenic expression in somatic cell hybrids. Adv Viral Oncol 1987; 6: 83
   Google Scholar
• Stanbridge E J, Flandermeyer R R, Daniels DW, et al. Specific chromosome loss associated with the expression of tumorigenicity in human cell hybrids. Somatic Cell Genet 1981; 7: 699–712
   PubMedGoogle Scholar
• Oshimura M, Koi M, Morita H, et al. Suppression of tumorigenecity of human cancer cell lines following chromosome transfer via microcell fusion. Proc Am Assoc Cancer Res 1989; 30: 786
   Google Scholar
• Trent J M, Stanbridge E J, McBride HL, et al. Tumorigenicity in human melanoma cell lines controlled by introduction of human chromosome 6. Science 1990; 247: 568–571
   PubMed Web of Science ®Google Scholar
• Dracopoli N C, Harnett P, Bale SJ, et al. Loss of alleles from the distal short arm of chromosome 1 occurs late in melanoma tumor progression. Proc Natl Acad Sci (USA) 1989; 86: 4614–4618
   PubMed Web of Science ®Google Scholar
• Weston A, Willey J C, Modali H, et al. Differential DNA sequence deletions from chromosomes 3, 11, 13, and 17 in squamous cell carcinoma, large cell carcinoma, and adenocarcinoma of the human lung. Proc Natl Acad Sci (USA) 1989; 86: 5099–5103
   PubMed Web of Science ®Google Scholar
• Kovacs G, Erlandsson R, Bolldog F, et al. Consistent chromosome 3p deletion and loss of heterozygosity in renal cell carcinoma. Proc Natl Acad Sci (USA) 1988; 85: 1571–1575
   PubMed Web of Science ®Google Scholar
• Yokota J, Tsukuda Y, Nakajima T, et al. Loss of heterozygosity on the short arm of chromosome 3 in carcinoma of the cervix. Cancer Res 1989; 49: 3598–3601
   PubMed Web of Science ®Google Scholar
• Green AR. Recessive mechanisms of malignancy. Br J Cancer 1988; 58: 115–121
   PubMed Web of Science ®Google Scholar
• Callahan R, Campbell G. Mutations in human breast cancer: an overview. J Natl Cancer Inst 1989; 81: 1780–1786
   PubMed Web of Science ®Google Scholar
• Fearon E R, Feinberg A P, Hamilton SH, et al. Loss of genes on the short arm of chromosome 11 in bladder cancer. Nature 1985; 318: 377–380
   PubMed Web of Science ®Google Scholar
• Comings DE. A general theory of carcinogenesis. Proc Natl Acad Sci (USA) 1973; 70: 3324–3328
   PubMed Web of Science ®Google Scholar
• De Mars R. In 23rd Ann. Symp. Fundamental Cancer Research Williams & Wilkins. Baltimore 1970; 105–106
   Google Scholar
• Knudson AG. Mutation and cancer: statistical study of retinoblastoma. Proc Natl Acad Sci (USA) 1971; 68: 820–823
   PubMed Web of Science ®Google Scholar
• Hansen M F, Cavenee WK. Genetics of cancer predisposition. Cancer Res 1987; 47: 5518–5527
   PubMed Web of Science ®Google Scholar
• Cavenee W K, Dryja T P, Phillips RA, et al. Expression of recessive alleles by chromosomal mechanisms in retinoblastoma. Nature 1983; 305: 779–784
   PubMed Web of Science ®Google Scholar
• Nakamura Y, Leppert M, O'Connell P, et al. Variable number of tandem repeat (VNTR) markers for human gene mapping. Science 1987; 235: 1616–1622
   PubMed Web of Science ®Google Scholar
• Cavenee W K, Hansen M K, Kock E, et al. Genetic origins of mutations predisposing to retinoblastoma. Science 1985; 228: 501–503
   PubMed Web of Science ®Google Scholar
• Ponder B. Gene losses in human tumours. Nature 1988; 335: 400–402
   PubMed Web of Science ®Google Scholar
• Seizinger B R, Breakefield XO. The role of “tumor suppressor” genes in neural tumors. Trends Neurosci 1990; 13: 3–6
   PubMed Web of Science ®Google Scholar
• Friend S H, Bernards R, Rogel S, et al. A human DNA segment with properties of the gene that predisposes to retinoblastoma and osteosarcoma. Nature 1986; 323: 643–646
   PubMed Web of Science ®Google Scholar
• Seizinger B R, Martuza R L, Gusella JF. Loss of genes on chromosome 22 in tumorigenesis of human acoustic neuroma. Nature 1986; 322: 644–647
   PubMed Web of Science ®Google Scholar
• Seizinger B R, de la Monte S, Atkins L, et al. Molecular genetic approach to human meningioma: Loss of genes on chromosome 22. Proc Natl Acad Sci (USA) 1987; 84: 5419–5423
   PubMed Web of Science ®Google Scholar
• El-Azouzi M, Chung R Y, Farmer GE, et al. Loss of distinct regions on the short arm of chromosome 17 associated with tumorigenesis of human astrocytomas. Proc Natl Acad Sci (USA) 1989; 86: 7186–7190
   PubMed Web of Science ®Google Scholar
• James C D, Carlbom E, Dumanski JP, et al. Clonal genomic alterations in glioma malignancy stages. Cancer Res 1988; 48: 5546–5551
   PubMed Web of Science ®Google Scholar
• James C D, Carlbom E, Nordenskjold M, et al. Mitotic recombination of chromosome 17 in astrocytomas. Proc Natl Acad Sci (USA) 1989; 86: 2858–2862
   PubMed Web of Science ®Google Scholar
• Fujimoto M, Fults D W, Thomas GA, et al. Loss of heterozygosity on chromosome 10 in human glioblastoma multiforme. Genomics 1989; 4: 210–214
   PubMed Web of Science ®Google Scholar
• Barker D, Wright E, Nguyen K, et al. Gene for von Recklinghausen neurofibromatosis is in the pericentromeric region of chromosome 17. Science 1987; 236: 1100–1102
   PubMed Web of Science ®Google Scholar
• Seizinger B R, Rouleau G A, Ozelius LJ, et al. Genetic linkage of von Recklinghausen neurofibromatosis to the nerve growth factor receptor gene. Cell 1987; 49: 589–594
   PubMed Web of Science ®Google Scholar
• Seizinger B R, Rouleau G A, Ozelius LJ, et al. Common pathogenetic mechanism for three tumor types in bilateral acoustic neurofibromatosis. Science 1987; 236: 317–319
   PubMed Web of Science ®Google Scholar
• Seizinger B R, Rouleau G A, Ozelius LJ, et al. Von Hippel-Lindau disease maps to the region of chromosome 3 associated with renal cell carcinoma. Nature 1988; 332: 268–269
   PubMed Web of Science ®Google Scholar
• Larsson C, Skogseid B, Oberg K, et al. Multiple endocrine neoplasia type 1 gene maps to chromosome 11 and is lost in insulinoma. Nature 1988; 332: 85–87
   PubMed Web of Science ®Google Scholar
• Mathew C GP, Smith B A, Thorpe K, et al. Deletion of genes on chromosome 1 in endocrine neoplasia. Nature 1987; 328: 524
   PubMed Web of Science ®Google Scholar
• Francke U. Retinoblastoma and chromosome 13. Cytogenet Cell Genet 1976; 16: 131
   PubMedGoogle Scholar
• Sparkes R S, Sparkes M C, Wilson MG, et al. Regional assignment of genes for human esterase D and retinoblastoma to chromosome band 13q14. Science 1980; 208: 1042–1044
   PubMed Web of Science ®Google Scholar
• Sparkes R S, Murphree A L, Lingua RW, et al. Gene for hereditary retinoblastoma assigned to chromosome 13 by linkage to esterase D. Science 1983; 219: 971–973
   PubMed Web of Science ®Google Scholar
• Lee W H, Bookstein R, Hong F, et al. Human retinoblastoma susceptibility gene: cloning, identification and sequence. Science 1987; 235: 1394–1399
   PubMed Web of Science ®Google Scholar
• Hong F D, Huang H-JS, To H, et al. Structure of the human retinoblastoma gene. Proc Natl Acad Sci (USA) 1989; 86: 5502–5506
   PubMed Web of Science ®Google Scholar
• Yandell D W, Campbell T A, Dayton SH, et al. Identification of cancer-causing point mutations in the human retinoblastoma gene and application to genetic counseling. N Engl J Med 1989; 321: 1689
   PubMed Web of Science ®Google Scholar
• Huang H-JS, Yee J-K, Shew J-Y, et al. Suppression of the neoplastic phenotype by replacement of the RB gene in human cancer cells. Science 1988; 242: 1563–1566
   PubMed Web of Science ®Google Scholar
• De Caprio J A, Ludlow J W, Figge J, et al. SV40 large T antigen forms a specific complex with the product of the retinoblastoma susceptibility gene. Cell 1988; 54: 275–283
   PubMed Web of Science ®Google Scholar
• Whyte P, Buchovich K J, Horowitz JM, et al. Association between an oncogene and an antioncogene: the adenovirus E1A proteins bind to the retinoblastoma gene product. Nature 1988; 334: 124–129
   PubMed Web of Science ®Google Scholar
• Dyson N, Howley P M, Munger K, et al. The human papilloma virus-16 E7 oncoprotein is able to bind to the retinoblastoma gene product. Science 1989; 243: 934–936
   PubMed Web of Science ®Google Scholar
• Green MR. When the products of oncogenes and anti-oncogenes meet. Cell 1989; 56: 1–3
   PubMed Web of Science ®Google Scholar
• Ruley HE. Adenovirus early region 1A enables viral and cellular transforming genes to transform primary cells in culture. Nature 1983; 304: 602–606
   PubMed Web of Science ®Google Scholar
• Fried M, Prives C. The biology of simian virus 40 and polyomavirus. Cancer Cells 1986; 4: 1–16
   Google Scholar
• Stabel S, Argos P, Philipson L. The release of growth arrest by microinjection of adenovirus E1A DNA. EMBO J 1985; 4: 2329–2336
   PubMed Web of Science ®Google Scholar
• Moran E, Mathews MB. Multiple functional domains in the adenovirus E1A gene. Cell 1987; 48: 177–178
   PubMed Web of Science ®Google Scholar
• Livingston D M, Bradley MK. Review: the simian virus 40 large T antigen-a lot packed into a little. Mol Biol Med d 1987; 4: 63–80
   PubMed Web of Science ®Google Scholar
• De Caprio J A, Ludlow J W, Lynch D, et al. The product of the retinoblastoma susceptibility gene has properties of a cell cycle regulatory element. Cell 1989; 58: 1085–1095
   PubMed Web of Science ®Google Scholar
• Buchovich K, Duffy L A, Harlow E. The retinoblastoma protein is phosphorylated during specific phases of the cell cycle. Cell 1989; 58: 1097–1105
   PubMed Web of Science ®Google Scholar
• Tjian R, Fey G, Graessmann A. Biological activity of purified simian virus 40 T antigen proteins. Proc Natl Acad Sci (USA) 1978; 75: 1279–1283
   PubMed Web of Science ®Google Scholar
• Ludlow J W, De Caprio J A, Huang C-M, et al. SV40 large T antigen binds preferentially to an underphosphorylated member of the retinoblastoma susceptibility gene product family. Cell 1989; 56: 57–65
   PubMed Web of Science ®Google Scholar
• Corallini A, Pagnani M, Viadana P, et al. Association of BK virus with human brain tumors and tumors of pancreatic islets. Int J Cancer 1987; 39: 60–67
   PubMed Web of Science ®Google Scholar
• Harbour J W, Lai S-L, Whang-Peng J, et al. Abnormalities in structure and expression of the human retinoblastoma susceptibility gene in SCLC. Science 1988; 241: 353–356
   PubMed Web of Science ®Google Scholar
• Bookstein R, Lee EY-H, Peccei A, et al. Human retinoblastoma gene: long-range mapping and analysis of its deletion in a breast cancer cell line. Mol Cell Biol 1989; 9: 1628–1634
   PubMed Web of Science ®Google Scholar
• Lee ET-H, To P, Shew J-Y, et al. Inactivation of the retinoblastoma susceptibility gene in human breast cancers. Science 1988; 241: 218–221
   PubMed Web of Science ®Google Scholar
• Horowitz J M, Yandell D W, Park S-H, et al. Point mutational inactivation of the retinoblastoma antioncogene. Science 1989; 243: 937–940
   PubMed Web of Science ®Google Scholar
• Toguchida J, Ishikazi K, Sasaki MS, et al. Preferential mutation of paternally derived RB gene as the initial event in sporadic osteosarcoma. Nature 1989; 338: 156–158
   PubMed Web of Science ®Google Scholar
• Lane D P, Crawford LV. T antigen is bound to a host protein in SV40-transformed cells. Nature 1979; 278: 261–263
   PubMed Web of Science ®Google Scholar
• Sarnow P, Ho Y S, Williams J, et al. Adenovirus E1B-58k tumor antigen and SV40 large tumor antigen are physically associated with the same 54kd cellular protein in transformed cells. Cell 1982; 28: 387
   PubMed Web of Science ®Google Scholar
• Eliyahu D, Raz A, Gruss P, et al. Participation of p53 cellular tumour antigen in transformation of normal embryonic cells. Nature 1984; 312: 646–649
   PubMed Web of Science ®Google Scholar
• Parada L F, Land H, Weinberg RA, et al. Cooperation between gene encoding p53 tumour antigen andrasin cellular transformation. Nature 1984; 312: 649–651
   PubMed Web of Science ®Google Scholar
• Finlay C A, Hinds P W, Levine AJ. The p53 proto-oncogene can act as a suppressor of transformation. Cell 1989; 57: 1083–1093
   PubMed Web of Science ®Google Scholar
• Benchimol S, Pim D, Crawford L. Radioimmunoassay of the cellular protein p53 in mouse and human cell lines. EMBO J 1982; 1055–1062
   PubMed Web of Science ®Google Scholar
• Mowat M, Cheng A, Kimura N, et al. Rearrangements of the cellular p53 gene in erythroleukemic cells transformed by Friend virus. Nature 1985; 314: 633–636
   PubMed Web of Science ®Google Scholar
• Wolf D, Rotter V. Major deletions in the gene encoding the p53 tumor antigen cause lack of p53 expression in HL-60 cells. Proc Natl Acad Sci (USA) 1985; 82: 790–794
   PubMed Web of Science ®Google Scholar
• Mercer W E, Nelson D, DeLeo AB, et al. Microinjection of monoclonal antibody to protein p53 inhibits serum-induced DNA synthesis in 3T3 cells. Proc Natl Acad Sci (USA) 1982; 79: 6309–6312
   PubMed Web of Science ®Google Scholar
• Shohat O, Greenberg M, Reisman D, et al. Inhibition of cell growth mediated by plasmids encoding p53 anti-sense. Oncogene 1987; 1: 277
   PubMed Web of Science ®Google Scholar
• Wang E H, Friedman P N, Prives C. The murine p53 protein blocks replication of SV40 DNA in vitro by inhibiting the initiation functions of SV40 large T antigen. Cell 1989; 57: 379–382
   PubMed Web of Science ®Google Scholar
• Masuda H, Miller C, Koeffler HP, et al. Rearrangement of the p53 gene in human osteogenic sarcomas. Proc Natl Acad Sci (USA) 1987; 84: 7716–7719
   PubMed Web of Science ®Google Scholar
• Takahashi T, Nau M M, Chiba I, et al. p53: a frequent target for genetic abnormalities in lung cancer. Science 1989; 246: 491–494
   PubMed Web of Science ®Google Scholar
• Baker S J, Fearon E R, Nigro JM, et al. Chromosome 17 deletions and p53 gene mutations in colorectal carcinomas. Science 1989; 244: 217–221
   PubMed Web of Science ®Google Scholar
• Nigro J M, Baker S J, Preisinger AC, et al. Mutations in the p53 gene occur in diverse human tumour types. Nature 1989; 342: 705–708
   PubMed Web of Science ®Google Scholar
• Chung R Y, Whaley J M, Yandell DW, et al. P53 gene mutations associated with the early appearance of the malignant phenotype in human adult astrocytomas, submitted for publication
   Google Scholar
• Menon A G, Anderson K M, Riccardi VM, et al. Chromosome 17p deletions and p53 gene mutations associated with neurofibrosarcomas from patients with NF1, submitted for publication
   Google Scholar
• Zulch KJ. Brain Tumors: Their Biology and Pathology3 ed. Springer Publishing, New York 1986
   Google Scholar
• Van Tuinen P, Rich D C, Summers KM, et al. Regional mapping panel for human chromosome 17: application to neurofibromatosis type 1. Genomics 1987; 1: 374
   PubMedGoogle Scholar
• Eliyahu D, Goldfinger N, Pinhasi-Kimhi O, et al. Meth A fibrosarcoma cells express two transforming mutant p53 species. Oncogene 1988; 3: 313
   PubMed Web of Science ®Google Scholar
• Rovinski B, Benchimol S. Immortalization of rat embryo fibroblasts by the cellular p53 oncogene. Oncogene 1988; 2: 445–452
   PubMed Web of Science ®Google Scholar
• Herskowitz I. Functional inactivation of genes by dominant negative mutations. Nature 1987; 329: 219–222
   PubMed Web of Science ®Google Scholar
• Knudson AG. Hereditary cancer, oncogenes, and antioncogenes. Cancer Res 1985; 45: 1437–1443
   PubMed Web of Science ®Google Scholar
• Noda M, Kitayama H, Matsuzaki T, et al. Detection of genes with a potential for suppressing the transformed phenotype associated with activatedrasgenes. Proc Natl Acad Sci (USA) 1989; 86: 162–166
   PubMed Web of Science ®Google Scholar
• Kitayama H, Sugimoto Y, Matsuzaki T, et al. Aras-related gene with transformation suppressor activity. Cell 1989; 56: 77–84
   PubMed Web of Science ®Google Scholar
• Zarling J M, Shoyab M, Marquardt H, et al. Oncostatin M: a growth regulator produced by differentiated histiocytic lymphoma cell. Proc Natl Acad Sci (USA) 1986; 83: 9729–9743
   PubMedGoogle Scholar
• Newmark P. Oncogenes and cell growth [news]. Nature 1987; 327: 101
   PubMed Web of Science ®Google Scholar
• Kimchi A, Wang X F, Weinberg RA, et al. Absence of TGF-beta receptors and growth inhibitory responses in retinoblastoma cells. Science 1988; 240: 196–199
   PubMed Web of Science ®Google Scholar
• Fearon E R, Cho K R, Nigro JM, et al. Identification of a chromosome 18q gene that is altered in colorectal cancers. Science 1990; 247: 49–56
   PubMed Web of Science ®Google Scholar
• Bos J L, Fearon E R, Hamilton SR, et al. Prevalence ofrasgene mutations in human colorectal cancers. Nature 1987; 327: 293–297
   PubMed Web of Science ®Google Scholar
• Forrester K, Almoguera M, Han K, et al. Detection of high incidence of K-rasoncogenes during human colon tumourigenesis. Nature 1987; 327: 298–303
   PubMed Web of Science ®Google Scholar
• Vogelstein B, Fearon E R, Dern SE, et al. Allelotype of colorectal carcinomas. Science 1989; 244: 207
   PubMed Web of Science ®Google Scholar
• Solmon E, Voss R, Hall V, et al. Chromosome 5 allele loss in human colorectal carcinomas. Nature 1987; 328: 616–619
   PubMed Web of Science ®Google Scholar
• Williams A F, Barclay AN. The immunoglobulin superfamily-domains for cell surface recognition. Ann Rev Immunol 1988; 6: 381
   PubMed Web of Science ®Google Scholar
• Hynes RO. Molecular biology of fibronectin. Ann Rev Cell Biol 1986; 1: 67
   Google Scholar
• Todaro G J, Green H. Quantitative studies of the growth of mouse embryo cells in culture and their development into established cell lines. J Cell Biol 1963; 17: 299
   PubMed Web of Science ®Google Scholar
• Fidler I J, Hart IR. Biologic diversity in metastatic neoplasms: origins and implications. Science 1982; 217: 998–1003
   PubMed Web of Science ®Google Scholar
• Greenberg M E, Brackenberry R, Edelman GM. Alteration of neural cell adhesion molecule (N-CAM) expression after neuronal cell transformation by Rous sarcoma virus. Proc Natl Acad Sci (USA) 1984; 81: 969–973
   PubMed Web of Science ®Google Scholar
• Pignatelli M, Bodmer WF. Genetics and biochemistry of collagen binding triggered glandular differentiation of a human colon carcinoma cell line. Proc Natl Acad Sci (USA) 1988; 85: 5561–5565
   PubMed Web of Science ®Google Scholar
• Marks P A, Sheffrey M, Rifkind RA, et al. Introduction of transformed cells to dermal differentiation and the modulation of gene expression. Cancer Res 1987; 47: 659–666
   PubMed Web of Science ®Google Scholar
• Folkman J, Cotran R. Relation of vascular proliferation to tumor growth. Int Rev Exp Pathol 1976; 16: 207–248
   PubMedGoogle Scholar
• Bouck N P, di Mayorca G. Chemical carcinogens transform BHK cells by inducing a recessive mutation. Mol Cell Biol 1982; 2: 97–105
   PubMed Web of Science ®Google Scholar
• Bouck N P, Head M. The majority of independently transformed BHK cell clones share a single functional lesion which determines anchorage independence and influences tumorigenicity. In Vitro Cell Dev Biol 1985; 21: 463–469
   PubMed Web of Science ®Google Scholar
• Bouck N P, Stoler A, Polverini PJ. Coordinate control of anchorage independence, actin cytoskeleton, and angiogenesis by human chromosome 1 in hamster-human hybrids. Cancer Res 1986; 46: 5101–5105
   PubMed Web of Science ®Google Scholar
• Stoler A, Bouck NP. Identification of a single chromosome in the normal genome essential for suppression of hamster cell transformation. Proc Natl Acad Sci (USA) 1985; 82: 570–574
   PubMed Web of Science ®Google Scholar
• Rastinejad F, Polverini P J, Bouck NP. Regulation of the activity of an new inhibitor of angiogenesis by a cancer suppressor gene. Cell 1989; 56: 345–355
   PubMed Web of Science ®Google Scholar
• Fong C-T, Dracopoli N C, White PS, et al. Loss of heterozygosity for the short arm of chromosome 1 in human neuroblastomas: Correlation with N-mycamplification. Proc Natl Acad Sci (USA) 1989; 86: 3753–3757
   PubMed Web of Science ®Google Scholar