Medical significance of Caenorhabditis elegans

References

• Wood W B. The nematode Caenorhabditis elegans. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY 1988
   Google Scholar
• C. eleguns II, D L Riddle, T Blumenthal, B J Meyer, J R Priess. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY 1997
   Google Scholar
• Sulston J E, Schierenberg E, White J G, Thomson J N. The embryonic cell lineage of the nematode Cuenorhabditis eleguns. Dev Biol 1983; 100: 64–119
   PubMed Web of Science ®Google Scholar
• Ruvkun G. Patterning the nervous system. C. eleguns II, D L Riddle, T Blumenthal, B J Meyer, J R Priess. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY 1997; 543–82
   Google Scholar
• White J G, Southgate E, Thompson J N, Brenner S. The structure of the nervous system of Cuenorhubditis eleguns. Philos Trans R Soc Lond 1987; 314: 1–340
   Google Scholar
• The C. eleguns sequencing consortium. Genome sequence of the nematode C. eleguns: a platform for investigating biology. Science 1998; 282: 2012–8
   PubMed Web of Science ®Google Scholar
• Wilson R K. How the worm was won. The C. eleguns genome sequencing project. Trends Genet 1999; 15: 51–8
   Google Scholar
• Sternberg P W, Han M. Genetics of RAS signalling in C. eleguns. Trends Genet 1998; 14: 466–72
   PubMedGoogle Scholar
• Metzstein M M, Stanfield G M, Horvitz H R. Genetics of programmed cell death in C. eleguns: past, present and future. Trends Genet 1998; 14: 410–6
   PubMed Web of Science ®Google Scholar
• Blaxter M. Cuenorhubditis eleguns is a Nematode. Science 1998; 282: 2041–6
   PubMed Web of Science ®Google Scholar
• Crompton D WT. How much human helminthiasis is there in the world. J Purisitol 1999; 85: 397–403
   PubMed Web of Science ®Google Scholar
• Burglin T R, Lobos E, Blaxter M L. Cuenorhubditis eleguns as a model for parasitic nematodes. Int J Purisitol 1998; 28: 395–411
   PubMed Web of Science ®Google Scholar
• Blattner F R, Plunkett G, 3rd, Bloch C A, Perna N T, Burland V, Riley M, et al. The complete genome sequence of Esche-richia coli K-12. Science 1997; 277: 1453–74
   PubMed Web of Science ®Google Scholar
• Goffeau A, Barrell B G, Bussey H, Davis R W, Dujon B, Feldmann H, et al. Life with 6000 genes. Science 1996; 274: 563–7
   Web of Science ®Google Scholar
• Dujon B. The Yeast Genome Project: What did we learn. Trends Genet 1996; 12: 263–70
   PubMed Web of Science ®Google Scholar
• Rubin G M. The Drosophila Genome Project: a progress report. Trends Genet 1998; 14: 340–3
   Google Scholar
• Waterston R, Sulston J E. The Human Genome Project: reaching the finishing line. Science 1998; 282: 53–4
   Google Scholar
• Gardner M J, Tettelin H, Carucci D J, Cummings L M, Aravind L, Koonin E V, et al. Chromosome 2 sequence of the human malaria parasite Plasmodium fulcipurum. Science 1998; 282: 1126–32
   PubMed Web of Science ®Google Scholar
• Johnston D A, Blaxter M L, Degrave W M, Foster J, Hens A C, Melville S E. Genomics and the biology of parasites. Bioessays 1999; 21: 131–47
   Google Scholar
• Brusca R C, Brusca G J. Invertebrates. Sinauer, Sunderland, MA 1990
   Google Scholar
• Nielsen C. Animal Evolution. Interrelationships of the Living Phyla. Oxford University Press, Oxford, UK 1995
   Google Scholar
• Aguinaldo A AM, Turbeville J M, Linford L S, Rivera M C, Garey J R, Raff R A, et al. Evidence for a clade of nematodes, arthropods and other moulting animals. Nature 1997; 387: 489–93
   PubMed Web of Science ®Google Scholar
• Adoutte A, Balavoine G, Lartillot N, deRosa R. Animal evolution: the end of the intermediate taxa. Trends Genet 1999; 15: 104–8
   PubMed Web of Science ®Google Scholar
• Sidow A, Thomas W K. A molecular evolutionary framework for eukaryotic model organisms. Curr Biol 1994; 4: 596–603
   PubMed Web of Science ®Google Scholar
• Mushegian A R, Garey J R, Martin J, Liu L X. Large-scale taxonomic profiling of eukaryotic model organisms: a comparison of orthologous proteins encoded by the human, fly, nematode, and yeast genomes. Genome Res 1998; 8: 590–8
   PubMed Web of Science ®Google Scholar
• de Rosa R, Grenier J K, Andreeva T, Cook C E, Adoutte A, Akam M, et al. Hox genes in brachiopods and priapulids and protostome evolution. Nature 1999; 399: 772–6
   Google Scholar
• Ruvkun G, Hobert O. The taxonomy of developmental control in Cuenorhubditis eleguns. Science 1998; 282: 2033–41
   PubMedGoogle Scholar
• Kokel M, Borland C Z, DeLong L, Horvitz H R, Stern M J. clr-1 encodes a receptor tyrosine phosphatase that negatively regulates an FGF receptor signaling pathway in Cuenorhubditis eleguns. Genes Dev 1998; 12: 1425–37
   PubMed Web of Science ®Google Scholar
• Chalfie M, Jorgensen E M. C. eleguns neuroscience: genetics to genome. Trends Genet 1998; 14: 506–12
   Google Scholar
• Meyer B J. Sex determination and X chromosome dosage compensation. C. eleguns II, D L Riddle, T Blumenthal, B J Meyer, J R Priess. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY 1997; 209–40
   Google Scholar
• Prasad B C, Randall R R. Chemosensation: molecular mechanisms in worms and mammals. Trends Genet 1999; 15: 150–3
   Google Scholar
• Hekimi S, Lakowski B, Barnes T M, Ewbank J J. Molecular genetics of life span in C. eleguns: how much does it teach us. Trends Genet 1998; 14: 14–20
   Google Scholar
• Mushegian A R, Bassett D E, Boguski M S, Bork P, Koonin E V. Positionally cloned human disease genes: patterns of evolutionary conservation and functional motifs. Proc Natl Acad Sci USA 1997; 94: 5831–6
   PubMed Web of Science ®Google Scholar
• Altschul S F, Gish W, Miller W, Myers E W, Lipman D J. Basic alignment search tool. J Mol Biol 1990; 215: 403–10
   PubMed Web of Science ®Google Scholar
• Ahringer J. Turn to the worm. Curr Opin Genet Dev 1997; 7: 410–5
   PubMedGoogle Scholar
• Collins J, Saari B, Anderson P. Activation of a transposable element in the germline but not the soma of Caenorhubditis eleguns. Nature 1987; 378: 726–8
   Google Scholar
• Mori I, Moerman D G, Waterson R H. Analysis of mutator activity necessary for germline transposition and excision of Tcl transposable elements in Cuenorhubditis eleguns. Genetics 1988; 120: 397–407
   PubMedGoogle Scholar
• Plasterk R HA. The year of the worm. Bioessuys 1999; 21: 105–9
   PubMedGoogle Scholar
• Rushforth A M, Saari B, Anderson P. Site-selected insertion of the transposon Tcl into a Caenorhabditis eleguns myosin light chain gene. Mol Cell Biol 1993; 13: 902–10
   PubMedGoogle Scholar
• Zwaal R R, Broeks A, van Meurs J, Groenen J TM, Plasterk R HA. Target-selected gene inactivation in Cuenorhubditis eleguns by using a frozen transposon insertion mutant bank. Proc Natl Acad Sci USA 1993; 90: 7431–5
   PubMed Web of Science ®Google Scholar
• Jansen G, Hazendonk E, Thijssen K L, Plasterk R HA. Reverse genetics by chemical mutagenesis in Caenorhabditis eleguns. Nut Genet 1998; 17: 119–21
   Google Scholar
• Fire A, Xu S, Montgomery M K, Kostas S A, Driver S E, Mello C C. Potent and specific genetic interference by double-stranded RNA in C eleguns. Nature 1998; 391: 806–11
   PubMed Web of Science ®Google Scholar
• Ketting R F, Haverkamp T H, van Leunen H G, Plasterk R HA. mut-7 of C. eleguns, required for transposon silencing and RNA interference, is a homolog of Werner Syndrome helicase and RnaseD. Cell 1999; 99: 133–41
   PubMed Web of Science ®Google Scholar
• Tabara H, Sarkissian M, Kelly W G, Fleenor J, Grishok A, Timmons L, et al. The rde-1 gene, RNA interference and transposon silencing in C.eleguns. Cell 1999; 99: 123–32
   PubMed Web of Science ®Google Scholar
• Fire A. RNA-triggered gene silencing. Trends Genet 1999; 9: 358–63
   Google Scholar
• Cuenorhabditis eleguns: modern biological analysis of an organism. Methods Cell Biol 1995; 48, Epstein HF, Shakes DC, eds.
   Google Scholar
• Miller D M, Shakes D C. Immunofluorescence microscopy. Methods Cell Biol 1995; 48: 365–94
   PubMedGoogle Scholar
• Seydoux G, Fire A. Whole-mount in situ hybridisation for the detection of RNA in Cuenorhubditis eleguns embryo. Methods Cell Biol 1995; 48: 323–37
   PubMed Web of Science ®Google Scholar
• Fire A, Harrison S W, Dixon D. A modular set of lacZ fusion vectors for studying gene expression in Caenorhabditis eleguns. Gene 1990; 93: 189–98
   PubMed Web of Science ®Google Scholar
• Chalfie M, Tu Y, Euskirchen G, Ward W W, Prasher D C. Green fluorescent protein as a marker for gene expression. Science 1994; 263: 802–5
   PubMed Web of Science ®Google Scholar
• Johnston M. Gene chips: array of hope for understanding gene regulation. Curr Biol 1998; 8: R171–4
   PubMed Web of Science ®Google Scholar
• DeVore D L, Horvitz H R, Stern M J. An FGF receptor signaling pathway is required for the normal cell migrations of the sex myoblasts in C. eleguns hermaphrodites. Cell 1995; 83: 611–20
   PubMed Web of Science ®Google Scholar
• Savage C, Das P, Finelli A L, Townsend S R, Sun C Y, Baud S E, et al. Caenorhubditis eleguns genes sma-2, sma-3, and sma-4 define a conserved family of transforming growth factor beta pathway components. Proc Natl Acad Sci USA 1996; 93: 790–4
   PubMedGoogle Scholar
• Swan K A, Severson A F, Carter J C, Martin P R, Schnabel H, Schnabel R, et al. cyk-1: a C. elegans FH gene required for a late step in embryonic cytokinesis. J Cell Sci 1998; 111: 2017–27
   PubMedGoogle Scholar
• Zhang Y, Emmons S W. Specification of sense-organ identity by a Caenorhabditis elegans Pax-6 homologue. Nature 1995; 377: 55–9
   Google Scholar
• Bashir R, Britton S, Strachan T, Keers S, Vafiadaki E, Lako M, et al. A gene related to Caenorhabditis elegans spermato-genesis actor fer-1 is mutated in limb-girdle muscular dystrophy type 2B. Nat Genet 1998; 20: 37–42
   PubMed Web of Science ®Google Scholar
• Levitan D, Greenwald I. Effects of SEL-12 presenilin on LIN-12 localisation and function in Caenorhabditis elegans. Development 1998; 125: 3599–606
   PubMedGoogle Scholar
• Wu G, Hubbard E J, Kitajewski J K, Greenwald I. Evidence for functional and physical association between Caenorhabditis elegans SEL-10, a Cdc4p-related protein, and SEL-12 presenilin. Proc Natl Acad Sci USA 1998; 95: 15787–91
   PubMedGoogle Scholar
• Ray W J, Yao M, Nowotny P, Mumm J, Zhang W, Wu J Y, et al. Evidence for physical interaction between presenilin and Notch. Proc Natl Acad Sci USA 1999; 96: 3263–8
   PubMedGoogle Scholar
• Barr M M, Sternberg P W. A polycystic kidney disease gene homologue required for male mating behaviour in C. elegans. Nature 1999; 401: 386–9
   PubMed Web of Science ®Google Scholar
• Alzheimer's Disease Collaborative Group. The structure of presenilin 1 (S182) gene and identification of six novel mutations in early onset AD families. Nat Genet 1995; 11: 219–22
   PubMed Web of Science ®Google Scholar
• Levitan D, Doyle T G, Brousseau D, Lee N K, Thinakaran G, Slunt H H, et al. Assessment of normal and mutant human presenilin function in Caenorhabditis elegans. Proc Natl Acad Sci USA 1996; 93: 14940–4
   Google Scholar
• Anderton B H. Alzheimer's disease: clues from flies and worms. Curr Biol 1999; 9: R106–9
   Google Scholar
• Faber P W, Alter J R, Macdonald M E, Hart A C. Poly-glutamine mediated dysfunction and apoptotic death of a Caenorhabditis elegans sensory neuron. Proc Natl Acad Sci USA 1999; 96: 179–84
   PubMed Web of Science ®Google Scholar
• Miller K G, Alfonso A, Nguyen M, Crowell J A, Johnson C D, Rand J B. A genetic selection for Caenorhabditis elegans synaptic transmission mutants. Proc Natl Acad Sci USA 1996; 93: 12593–8
   Google Scholar
• Tan M W, Rahme L G, Sternberg J A, Tompkins R G, Ausubel F M. Pseudomonas aeruginosa killing of Caenorhabditis elegans used to identify P. aeruginosa virulence factors. Proc Natl Acad Sci USA 1999; 96: 2408–13
   PubMed Web of Science ®Google Scholar
• Blaxter M L, De Ley P, Garey J R, Liu L X, Scheldeman P, Vierstraete A, et al. A molecular evolutionary framework for the phylum Nematoda. Nature 1998; 392: 71–5
   PubMed Web of Science ®Google Scholar
• Dorris M, De Ley P, Blaxter M L. Molecular analysis of Nematode diversity and the evolution of parasitism. Parasitol Today 1999; 15: 188–93
   PubMedGoogle Scholar
• Blaxter M L. The Filarial Genome Project. Parasitol Today 1995; 11: 811–2
   Google Scholar
• Willams S A. Deep within the filarial genome: progress of the filarial genome project. Parasitol Today 1999; 15: 219–24
   Google Scholar
• Daub J, Loukas A, Pritchard D I, Blaxter M L. A survey of genes expressed in adults of the human hookworm Necator americunus. Parasitology
   Google Scholar
• Grant W N. Transformation of Caenorhabditis elegans with genes from parasitic nematodes. Parasitol Today 1992; 8: 344–6
   PubMedGoogle Scholar
• Kwa M SG, Veenstra J C, Van Dijk W, Roos M H. Beta-tubulin genes from the parasitic nematode Haemonchus contortus modulate drug-resistance in Caenorhabditis elegans. J Mol Biol 1995; 246: 500–10
   Google Scholar