References
- Pyeritz R E., McKusick V. The Marfan syndrome: Diagnosis and management. N Engl J Med 1979; 5: 772–7
- Dietz H C., Cutting G R., Pyeritz R E., et al. Marfan syndrome caused by a recurrent de novo missense mutation in the fibrillin gene. Nature 1991; 352: 337–339
- Kainulainen K, Savolainen A, Palotie A, Kaitila J, Rosenbloom J, Peltonen L. Marfan syndrome: Exclusion of genetic linkage to five genes coding for connective tissue components in the long arm of chromosome 2. Hum Genet 1990; 84: 233–6
- Blanton S, Sarfarazi M, Eiberg H, et al. An exclusion map of Marfan syndrome. J Med Genet 1991; 27: 73–7
- Kainulainen K, Pulkkinen L, Savolainen A, Kaitila I, Peltonen L. Location on chromosome 15 of the gene defect causing Marfan syndrome. N Engl J Med 1990; 323: 935–9
- Kainulainen K, Steinmann B, Collins F, et al. Marfan syndrome: No evidence for heterogeneity in different populations and more precise mapping of the gene. Am J Hum Genet 1991, in press
- Sakai L Y. Fibrillin, a new 350-kD glycoprotein, is a component of extracellular microfibrils. J Cell Biol 1986; 103: 2499–509
- Godfrey M, Olson S, Burgio R G., et al. Unilateral microfibrillar abnormalities in a case of asymmetric Marfan syndrome. Am J Hum Genet 1990; 46: 661–71
- Godfrey M, Menashe V, Weleger G, et al. Cosegregation of elastin-associated microfibrillar abnormalities with the Marfan phenotype in families. Am J Hum Genet 1990; 46: 652–60
- Hollister D W., Godfrey M, Sakai L Y., Pyeritz R E. Immuno-histologic abnormalities of the microfibrillar-fiber system in the Marfan syndrome. N Engl J Med 1990; 323: 152–9
- Magenis R E., Smith L, Allen L, Sakai L. Localization of the fibrillin gene to chromosome 15, band 15q21.1. Genomics 1991, in press
- Dietz H C., Pyeritz R E., Hall B D., et al. The Marfan syndrome locus: conformation of assignment to chromosome 15 and identification of tightly linked markers at 15q15–q213. Genomics 1991; 9: 355–61
- Tsipouras P, Sarfarazi M, Devi A, Weiffenbach B, Boxer M. Marfan syndrome is closely linked to a marker on chromosome 15q15–q21. Proc Natl Acad Sci USA 1991; 88: 4486–8