References
- Tanti A, Belzung C. Neurogenesis along the septo-temporal axis of the hippocampus: are depression and the action of antidepressants region-specific? Neuroscience 2013;252:234–52.
- Pariante CM, Lightman SL. The HPA axis in major depression: classical theories and new developments. Trends Neurosci 2008;31:464–8.
- Cai S, Huang S, Hao W. New hypothesis and treatment targets of depression: an integrated view of key findings. Neurosci Bull 2015.
- Holsboer F. The corticosteroid receptor hypothesis of depression. Neuropsychopharmacology 2000;23:477–501.
- McEwen BS, Gould EA, Sakai RR. The vulnerability of the hippocampus to protective and destructive effects of glucocorticoids in relation to stress. Br J Psychiatry Suppl 1992;18–23.
- Caratti G, Matthews L, Poolman T, Kershaw S, Baxter M, Ray D. Glucocorticoid receptor function in health and disease. Clin Endocrinol (Oxf) 2015.
- Anacker C, Zunszain PA, Carvalho LA, Pariante CM. The glucocorticoid receptor: pivot of depression and of antidepressant treatment? Psychoneuroendocrinology 2011;36:415–25.
- Hepgul N, Cattaneo A, Zunszain PA, Pariante CM. Depression pathogenesis and treatment: what can we learn from blood mRNA expression? BMC Med 2013;11:28.
- Rojas PS, Fritsch R, Rojas RA, Jara P, Fiedler JL. Serum brain-derived neurotrophic factor and glucocorticoid receptor levels in lymphocytes as markers of antidepressant response in major depressive patients: a pilot study. Psychiatry Res 2011;189:239–45.
- Cattaneo A, Gennarelli M, Uher R, Breen G, Farmer A, Aitchison KJ, Craig IW, Anacker C, Zunsztain PA, McGuffin P, Pariante CM. Candidate genes expression profile associated with antidepressants response in the GENDEP Study: Differentiating between baseline 'Predictors' and longitudinal 'Targets'. Neuropsychopharmacology 2013;38:377–85.
- Matsubara T, Funato H, Kobayashi A, Nobumoto M, Watanabe Y. Reduced glucocorticoid receptor alpha expression in mood disorder patients and first-degree relatives. Biol Psychiatry 2006;59:689–95.
- Knorr U, Vinberg M, Klose M, Feldt-Rasmussen U, Hilsted L, Gade A, et al. Rationale and design of the participant, investigator, observer, and data-analyst-blinded randomized AGENDA trial on associations between gene-polymorphisms, endophenotypes for depression and antidepressive intervention: the effect of escitalopram versus placebo on the combined dexamethasone-corticotrophine releasing hormone test and other potential endophenotypes in healthy first-degree relatives of persons with depression. Trials 2009;10:66.
- Knorr U, Kessing LV. The effect of selective serotonin reuptake inhibitors in healthy subjects. A systematic review. Nord J Psychiatry 2010;64:153–63.
- Goldstein BL, Klein DN. A review of selected candidate endophenotypes for depression. Clin Psychol Rev 2014;34:417–27.
- Knorr U, Vinberg M, Hansen A, Klose M, Feldt-Rasmussen U, Hilsted L, et al. in healthy first-degree relatives to depressed patients - a randomized placebo-controlled trial. PLoS One 2011;6:e2124.
- Knorr U, Vinberg M, Gether U, Winkel P, Gluud C, Wetterslev J, Kessing LV. The effect of escitalopram versus placebo on perceived stress and salivary cortisol in healthy first-degree relatives of patients with depression-. A Randomised Trial Psychiatry Res 2012;200:354–60.
- Bock C, Bukh JD, Vinberg M, Gether U, Kessing LV. Validity of the diagnosis of a single depressive episode in a case register. Clin Pract Epidemol Ment Health 2009;5:4.
- Wing JK, Babor T, Brugha T, Burke J, Cooper JE, Giel R, et al. SCAN. Schedules for Clinical Assessment in Neuropsychiatry Arch Gen Psychiatry 1990;47:589–93.
- The Structured Clinical Interview for DSM - IV Axis II Personality Disorders (SCID - II). Washington DC: American Psychiatric Press, 1997.
- Cohen S, Kamarck T, Mermelstein R. A global measure of perceived stress. J Health Soc Behav 1983;24:385–96.
- Koga Y, Matsuzaki A, Suminoe A, Hattori H, Kanemitsu S, Hara T. Differential mRNA expression of glucocorticoid receptor alpha and beta is associated with glucocorticoid sensitivity of acute lymphoblastic leukemia in children. Pediatr Blood Cancer. 2005;45:121–7.
- Holm S. A simple sequentially rejective multiple test procedure. Scandinavian Journal of Statistics 1979;6:65–70.
- Jacobs RH, Orr JL, Gowins JR, Forbes EE, Langenecker SA. Biomarkers of intergenerational risk for depression: a review of mechanisms in longitudinal high-risk (LHR) studies. J Affect Disord 2015;175C:494–506.