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Immunological Investigations
A Journal of Molecular and Cellular Immunology
Volume 39, 2010 - Issue 1
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Research Article

Immunomodulatory Effects of Radiofrequency Ablation in a Breast Cancer Model

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Pages 74-92 | Published online: 12 Jan 2010

REFERENCES

  • Anderson, K.M., Srivastava, P.K. (2000). Heat, heat shock, heat shock proteins and death: a central link in innate and adaptive immune responses. Immunol. Lett. 74:35–39.
  • Basu, S., Binder, R., Suto, R., Anderson, K., Srivastava, P. K. (2000). Necrotic but not apoptotic cell death releases heat shock proteins, which deliver a partial maturation signal to dendritic cells and activate the NF-kB pathway. Int. Immunol. 12:1539.
  • Bates, G. J., Fox, S. B., Han, C., Leek, R. D., Garcia, J. F., Harris, A. L., Banham, A. H. (2006). Quantification of regulatory T cells enables the identification of high-risk breast cancer patients and those at risk of late relapse. J. Clin. Oncol. 24:5373–5380.
  • Bland, K.L., Gass, J., Klimberg, V.S. (2007). Radiofrequency, cryoablation, and other modalities for breast cancer ablation. Surg. Clin. North Am. 87(2):539–550.
  • Ciocca, D.R., Calderwood, S.K. (2005). Heat shock proteins in cancer:diagnostic, prognostic, predictive, and treatment implications. Cell Stress Chaperones 10(2):86–103.
  • Clark, P. R., Menoret, A. (2001). The inducible Hsp70 as a marker of tumor immunogenicity. Cell Stress Chaperones 6:121–125.
  • Curiel, T. J., Coukos, G., Zou, L., Alvarez, X., Cheng, P., Mottram, P., Evdemon-Hogan, M., Conejo-Garcia, J. R., Zhang, L., Burow, M., Zhu, Y., Wei, S., Kryczek, I., Daniel, B., Gordon, A., Myers, L., Lackner, A., Disis, M. L., Knutson, K. L., Chen, L., Zou, W. (2004). Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege and predicts reduced survival. Nat. Med. 10:942–949.
  • den Brok, M. H., Sutmuller, R. P., Nierkens, S., Bennink, E.J., Frielink, C., Toonen, L. W., Boerman, O. C., Figdor, C. G., Ruers, T. J., Adema, G. J. (2006). Efficient loading of dendritic cells following cryo and radiofrequency ablation in combination with immune modulation induces anti-tumour immunity. Br. J. Cancer 95:896–905.
  • Diefenbach, A., Jensen, E. R., Jamieson, A. M., Raulet, D. H. (2001). Rae1 and H60 ligands of the NKG2D receptor stimulate tumour immunity. Nature (Lond.) 413:165–171.
  • Fagnoni, F. F., Ferrari, C., Missale, G. (2006). Radiofrequency thermal ablation of hepatocellular carcinoma liver nodules can activate and enhance tumor-specific T-cell responses. Cancer Res. 66(2):1139–1146.
  • Fisher, E. R., Anderson, S., Tan-Chiu, E., Fisher, B., Eaton, L., Wolmark, N. (2001). Fifteen-year prognostic discriminants for invasive breast carcinoma: national surgical adjuvant breast and bowel project protocol-06. Cancer Supplement 91(8):1679–1687.
  • Fortin, A., Larochelle, M., Laverdière, J., Lavertu, S., Tremblay, D. (1999). Local failure is responsible for the decrease in survival for patients with breast cancer treated with conservative surgery and postoperative radiotherapy. J. Clin. Oncol. 17(1):101–109.
  • Goldberg, S. N., Gazelle, G. S., Mueller, P. R. (2000). Thermal ablation therapy for focal malignancy: a unified approach to underlying principles, techniques, and diagnostic imaging guidance. Am. J. Roentgenol. 174(2):323–331.
  • Golgher, D., Jones, E., Powrie, F., Elliott, T., Gallimore, A. (2002). Depletion of CD25_ regulatory cells uncovers immune responses to shared murine tumor rejection antigens. Eur. J. Immunol. 32:3267–3275.
  • Gonzalez, H. D., Figueras, J. (2007). Effect of surgical resection of metastatic disease on immune tolerance to cancer. How a systemic disease could be controlled by a local therapy. Clin. Transl. Oncol. 9:571.
  • Grieco, C. A., Simon, C. J., Mayo-Smith, W. W., DiPetrillo, T. A., Ready, N. E., Dupuy, D. E. (2006). Percutaneous image-guided thermal ablation and radiation therapy: outcomes of combined treatment for 41 patients with inoperable stage I/II non-small-cell lung cancer. J. Vasc. Interv. Radiol. 17(7):1117–1124.
  • Hansler, J., Wissniowski, T. T., Schuppan, D., Witte, A., Bernatik, T., Hahn, E. G., Strobel, D. (2006). Activation and dramatically increased cytolytic activity of tumor specifi c T lymphocytes after radio-frequency ablation in patients with hepatocellular carcinoma and colorectal liver metastases. World J. Gastroenterol. 12(23):3716–3721.
  • Jaattela, M. (1999). Heat shock proteins as cellular lifeguards. Ann. Med. 31:261–271.
  • Jarnicki, A.G., Lysaght, J., Todryk, S., Mills, K. H. (2006). Suppression of antitumor immunity by IL-10 and TGF-beta-producing T cells infiltrating the growing tumor: influence of tumor environment on the induction of CD4+ and CD8+ regulatory T cells. J. Immunol. 177(2):896–904.
  • Jordan, M., Boesteanu, A., Reed, A., Petrone, A., Holenbeck, A., Lerman, M., Naji, A., Caton, A. (2001). Thymic selection of CD4+CD25+ regulatory T cells induced by an agonist self-peptide. Nat. Immunol. 2:301–306.
  • Kelly, J. M., Darcy, P. K., Markby, J. L., Godfrey, D. I., Takeda, K., Yagita, H., Smyth, M. J. (2002). Induction of tumor-specific T cell memory by NK cell-mediated tumor rejection. Nat. Immunol. 3:83–90.
  • Kenderov, A., Minkova, V., Mihailova, D., Giltiay, N., Kyurkchiev, S., Kehayov, I., Kaveri, S., Kazatchkine, M., Pashov, A. (2002). Lupus specific kidney deposits of HSP90 are associated with altered IgG iditypic interactions of anti-HSP90 autoantibodies. Clin. Exp. Immunol. 129:169–176.
  • Kitani, A., Chua, K., Nakamura, K., Strober, W. (2000). Activated self-MHC-reactive T cells have the cytokine phenotype of Th3/T regulatory cell 1 T cells. J. Immunol. 165:691–702.
  • Klimberg, V. S., Kepple, J., Shafirstein, G., Adkins, L., Henry-Tillman, R., Youssef, E., Brito, J., Talley, L., Korourian, S. (2006). eRFA: Excision followed by RFA—A new technique to improve local control in breast cancer. Ann. Surg. Oncol. 13(11):1422–1433.
  • Kobayashi, N., Hiraoka, N., Yamagami, W., Ojima, H., Kanai, Y., Kosuge, T., Nakajima, A., Hirohashi, S. (2007). FOXP3+ regulatory T cells affect the development and progression of hepatocarcinogenesis. Clin. Cancer Res. 13:902–911.
  • Li, Z. (1997). Priming of T cells by heat shock protein-peptide complexes as the basis of tumor vaccines. Semin. Immunol. 9:315–322.
  • Li, Z. (2001). The roles of heat shock proteins in tumor immunity. Cancer. Chemother. Biol. Response Modif. 19:371–383.
  • Lindquist, S., Craig, E. A. (1988). The heat shock proteins. Ann. Rev. Genetics 22:631–677.
  • Liyanage, U. K., Moore, T. T., Joo, H. G., Tanaka, Y., Herrmann, V., Doherty, G., Drebin, J. A., Strasberg, S. M., Eberlein, T. J., Goedegebuure, P. S., Linehan, D. C. (2002). Prevalence of regulatory T cells is increased in peripheral blood and tumor microenvironment of patients with pancreas or breast adenocarcinoma. J. Immunol. 169:2756–2761.
  • MacConmara, M. P., Maung, A. A., Fujimi, S., McKenna, A. M., Delisle, A., Lapchak, P. H., Rogers, S., Lederer, J. A., Mannick, J. A. (2006). Increased CD4+ CD25+ T regulatory cell activity in trauma patients depresses protective Th1 immunity. Ann. Surg. 244:514–523.
  • Manzo, G. (1998). Natural killer cell reactivity: activation and cytolysis mechanism models, involving heat shock protein, haemopoietic histocompatibility, major histocompatibility complex and complement molecules. Med. Hypotheses 51:5–9.
  • Massa, C., Guiducci, C., Arioli, I., Parenza, M., Colombo, M. P., Melani, C. (2004). Enhanced efficacy of tumor cell vaccines transfected with secretable hsp70. Cancer Res. 64:1502–1508.
  • Matsuura, K. Y., Yamaguchi, H., Ueno, A., Osaki, K., Arihiro, K., Toge, T. (2006). Maturation of dendritic cells and T-cell responses in sentinel lymph nodes from patients with breast carcinoma. Cancer 106:1227.
  • Melcher, A., Todryk, S., Hardwick, N., Ford, M., Jacobson, M., Vile, R. G. (1998). Tumor immunogenicity is determined by the mechanism of cell death via induction of heat shock protein expression. Nat. Med. 4:581–587.
  • Menoret, A., Patry, Y., Burg, C., Le Pendu, J. (1995). Co-segregation of tumor immunogenicity with expression of inducible but not constitutive hsp70 in rat colon carcinomas. J. Immunol. 155:740–747.
  • Morimoto, R. I., Santoro, M. G. (1998). Stress-inducible responses and heat shock proteins: new pharmacologic targets for cytoprotection. Nat. Biotechnol. 16:833–838.
  • Multoff, G. (2002). Activation of natural killer cells by heat shock protein 70. Int J. Hyperthermia 18(6):576–585.
  • Multhof, G., Pfister, K., Gehrmann, M., Hantschel, M., Gross, C., Hafner, M., Hiddemann, W. (2001). A 14-mer Hsp70 peptide stimulates NK cell activity. Cell Stress Chaperones 6:337–344.
  • Ni Choileain, N. M., MacConmara, Y., Zang, T. J., Murphy, J. A., Mannick, J., Lederer, J. A. (2006). Enhanced regulatory T cell activity is an element of the host response to injury. J. Immunol. 176:225–236.
  • Nielsen, C. H., Leslie, R. G., Jepsen, B. S., Kazatchkine, M. D., Kaveri, S. V., Fischer, E. (2001). Natural autoantibodies and complement promote the uptake of a self antigen, human thyroglobulin, by B cells and the proliferation of thyroglobulin-reactive CD4(+) T cells in healthy individuals. Eur. J. Immunol. 31:2660–2668.
  • Pashov, A., Kenderov, A., Kyurkchiev, S., Kehayov, I., Hristova, S., Lacroix-Desmazes, S., Giltiay, N., Sooryanarayana, N., Kazatchkine, M. D., Kaveri, S. V. (2002). Autoantibodies to heat shock protein 90 (HSP90) in the human natural antibody repertoire. Int. Immunol. 14:453–461.
  • Pashov, A., Monzavi-Karbassi, B., Chow, M., Cannon, M., Kieber-Emmons, T. (2007). Immune surveillance as a rationale for immunotherapy?. Hum. Vaccine 3:224–228.
  • Peng, P., Ménoret, A., Srivastava, P. K. (1997). Purification of immunogenic heat shock protein 70-peptide complexes by ADP-affinity chromatography. J. Immunol. Meth. 204:13–21.
  • Polak, M. E., Borthwick, N. J., Gabriel, F. G., Johnson, P., Higgins, B., Hurren, J., McCormick, D., Jager, M. J., Cree, I. A. (2007). Mechanisms of local immunosuppression in cutaneous melanoma. Br. J. Cancer 96:1879.
  • Rossi, S., Buscarini, E., Garbagnati, F., (1998). Percutaneous treatment of small hepatic tumors by an expandable RF needle electrode. Am J Roentgenol 170:1015–1022.
  • Sakaguchi, S. (2003). The origin of FOXP3-expressing CD4+ regulatory T cells: thymus or periphery. J. Clin. Invest. 112:1310–1312.
  • Sakaguchi, S. (2004). Naturally arising CD4+ regulatory T cells for immunologic self-tolerance and negative control of immune responses. Annu. Rev. Immunol. 22:531–562.
  • Sasada, T. M., Kimura, Y., Yoshida, M., Kanai, M., Takabayashi, A. (2003). CD4+CD25+ regulatory T cells in patients with gastrointestinal malignancies: possible involvement of regulatory T cells in disease progression. Cancer 98:1089.
  • Schhuller, G., Kettenbach, J., Sedivy, R., Stift, A., Friedl, J., Gnant, M., Lammer, J. (2004). Heat shock protein expression induced by percutaneous radiofrequency ablation of hepatocellular carcinoma in vivo. Inter. J. Oncol. 24:609–613.
  • Shevach, E. M. (2002). CD4+ CD25+ suppressor T cells: more questions than answers. Nat. Rev. Immunol 2:389.
  • Shinnick, T. M. (1991). Heat shock proteins as antigens of bacterial and parasitic pathogens. Curr. Top. Microbiol. Immunol. 167:145–160.
  • Singletary, E. S. (2002). Surgical margins in patients with early-stage breast cancer treated with breast conservation therapy. Amer. J. Surg. 184:383–393.
  • Srivastava, P. K. (2005). Immunotherapy for human cancer using heat shock protein-peptide complexes. Curr. Oncol. Rep. 7(2):104–108.
  • Srivastava, P. K., Udono, H. (1994). Heat shock protein-peptide complexes in cancer immunotherapy. Curr. Opin. Immunol. 6:728–732.
  • Todryk, S., Melcher, A., Hardwick, N., Linardakis, E., Bateman, A., Colombo, M.P., (1999). Heat shock protein 70 induced during tumor cell killing induces Th1 cytokines and targets immature dendritic cell precursors to enhance antigen uptake. J. Immunol. 163:1398.
  • Tokuno, K., Hazama, S., Yoshino, S., Yoshida, S., Oka, M. (2009). Increased prevalence of regulatory T-cells in the peripheral blood of patients with gastrointestinal cancer. Anticancer Res. 29:1527–1532.
  • Udono, H., Srivastava, P. K. (1993). Heat shock protein 70-associated peptides elicit specific cancer immunity. J. Exp. Med. 178:1391–1395.
  • Vieweg, J., Su, Z., Dahm, P., Kusmartsev, S. (2007). Reversal of tumor-mediated immunosuppression. Clin. Cancer Res. 13(2 Pt 2):727s–732s.
  • Viguier, M. F., Lemaitre, O., Verola, M. S., Cho, G., Gorochov, L., Dubertret, H., Bachelez, P., Kourilsky, P., Ferradini, L. (2004). Foxp3 expressing CD4+CD25(high) regulatory T cells are overrepresented in human metastatic melanoma lymph nodes and inhibit the function of infiltrating T cells. J. Immunol. 173:1444.
  • Welch, W. J. (1992). Mammalian stress response: cell physiology, structure/ function of stress proteins, and implications of medicine and disease. Physiolog. Rev. 172(4):1063–1081.
  • Wolf, A. M., Wolf, D., Steurer, M., Gastl, G., Gunsilius, E., Grubeck-Loebenstein, B. (2003). Increase of regulatory T cells in the peripheral blood of cancer patients. Clin. Cancer Res. 9:606.
  • Woo, E. Y., Chu, C. S., Goletz, T. J., Schlienger, K., Yeh, H., Coukos, G., Rubin, S. C., Kaiser, L. R., June, C. H. (2001). Regulatory CD4_CD25_ T cells in tumors from patients with early-stage non-small cell lung cancer and late-stage ovarian cancer. Cancer Res. 61:4766–4772.
  • Wu, F., Wang, Z. B., Lu, P., Xu, Z. L., Chen, W. Z., Zhu, H., Jin, C. B. (2004). Activated anti-tumor immunity in cancer patients after high intensity focused ultrasound ablation. Ultrasound Med. Biol. 30:1217–1222.
  • Zerbini, A., Pilli, M., Penna, A., Pelosi, G., Schianchi, C., Molinari, A., Schivazappa, S., Zibera, C., Zhu, X., Zhao, X., Burkholder, W. F., Gragerov, A., Ogata, C. M., Gottesman, M. E., Hendrickson, W. A. (1996). Structural analysis of substrate binding of the molecular chaperone DnaK. Science 272:1606–1614.
  • Zhu, X., Zhao, X., Burkholder, W. F., Gragerov, A., Ogata, C. M., Gottesman, M. E., Hendrickson, W. A. (1996). Structural analysis of substrate binding by the molecular chaperone Dnak. Science 272:1606–1614.
  • Zlotta, A. R., Wildschutz, T., Raviv, G., (1997). Radiofrequency interstitial tumor ablation (RITA) is a possible new modality for treatment of renal cancer: ex vivo and in vivo experience. J. Endourol. 11:251–258.

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