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Immunological Investigations
A Journal of Molecular and Cellular Immunology
Volume 42, 2013 - Issue 3
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Research Article

Age-Associated Changes in MicroRNA Expression in Bone Marrow Derived Dendritic Cells

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Pages 179-190 | Published online: 19 Dec 2012

REFERENCES

  • Agrawal, A., Agrawal, S., Cao, J. N., Su, H., Osann, K., Gupta, S. (2007). Altered innate immune functioning of dendritic cells in elderly humans: a role of phosphoinositide 3-kinase-signaling pathway. J. Immunol. 178:6912–6922.
  • Bartel, D. P. (2004). MicroRNAs: genomics, biogenesis, mechanism, and function. Cell 116:281–297.
  • Ciaramella, A., Spalletta, G., Bizzoni, F., Salani, F., Caltagirone, C., Bossù, P. (2011). Effect of age on surface molecules and cytokine expression in human dendritic cells. Cell Immunol. 269:82–89.
  • Dorshkind, K., Montecino-Rodriguez, E., Signer, R. A. (2000). The ageing immune system: is it ever too old to become young again? Nat. Rev. Immunol. 9:57–62.
  • Drummond, M. J., McCarthy, J. J., Sinha, M., Spratt, H. M., Volpi, E., Esser, K. A., Rasmussen, B. B. (2011). Aging and microRNA expression in human skeletal muscle: a microarray and bioinformatics analysis. Physiol. Genom. 43:595–603.
  • Fatica, A., Rosa, A., Ballarino, M., De Marchis, M. L., Rasmussen, K. D., Bozzoni, I. (2008). Role of microRNAs in myeloid differentiation. Biochem. Soc. Trans. 36:1201–1205.
  • Gorospe, M., Abdelmohsen, K. (2011). MicroRegulators come of age in senescence. Trends Genet. 27:233–241.
  • Grolleau-Julius, A., Garg, M. R., Mo, R., Stoolman, L. L., Yung, R. L. (2006). Effect of aging on bone marrow-derived murine CD11c+CD4-CD8alpha- dendritic cell function. J. Gerontol. A Biol. Sci. Med. Sci. 61:1039–1047.
  • Grolleau-Julius, A., Harning, E. K., Abernathy, L. M., Yung, R. L. (2008). Impaired dendritic cell function in aging leads to defective antitumor immunity. Cancer Res. 68:6341–6349.
  • Johnnidis, J. B., Harris, M H., Wheeler, R. T., Stehling-Sun, S., Lam, M. H., Kirak, O., Brummelkamp, T. R., Fleming, M. D., Camargo, F. D. (2008). Regulation of progenitor cell proliferation and granulocyte function by microRNA-223. Nature 451:1125–1129.
  • Jurkin, J., Schichl, Y. M., Koeffel, R., Bauer, T., Richter, S., Konradi, S., Gesslbauer, B., Strobl, H. (2010). miR-146a is differentially expressed by myeloid dendritic cell subsets and desensitizes cells to TLR2-dependent activation. J. Immunol. 184:4955–4965.
  • Kovacs, E. J., Palmer, J. L., Fortin, C. F., Fülöp, T. Jr., Goldstein, D. R., Linton, P. J. (2009). Aging and innate immunity in the mouse: impact of intrinsic and extrinsic factors. Trends Immunol. 30:319–324.
  • Martinez-Nunez, R. T., Louafi, F., Friedmann, P. S., Sanchez-Elsner, T. (2009). MicroRNA-155 modulates the pathogen binding ability of dendritic cells (DCs) by down-regulation of DC-specific intercellular adhesion molecule-3 grabbing non-integrin (DC-SIGN). J. Biol. Chem. 284:16334–16342.
  • Min, H., Montecino-Rodriguez, E., Dorshkind, K. (2005). Effects of aging on early B- and T-cell development. Immunol. Rev. 205:7–17.
  • Noren Hooten, N., Abdelmohsen, K., Gorospe, M., Ejiogu, N., Zonderman, A. B., Evans, M. K. (2010). microRNA expression patterns reveal differential expression of target genes with age. PLoS One 5:e10724.
  • O’Connell, R. M., Rao, D. S., Chaudhuri, A. A., Boldin, M. P., Taganov, K. D., Nicoll, J., Paquette, R. L., Baltimore, D. (2008). Sustained expression of microRNA-155 in hematopoietic stem cells causes a myeloproliferative disorder. J. Exp. Med. 205:585–594.
  • O’Connell, R. M., Zhao, J. L., Rao, D. S. (2011). MicroRNA function in myeloid biology. Blood 118:2960–2969.
  • Panda, A., Arjona, A., Sapey, E., Bai, F., Fikrig, E., Montgomery, R. R., Lord, J. M., Shaw, A. C. (2009). Human innate immunosenescence: causes and consequences for immunity in old age. Trends Immunol. 30:325–333.
  • Persengiev, S. P., Kondova, I. I., Bontrop, R. E. (2012). The impact of MicroRNAs on brain aging and neurodegeneration. Curr. Gerontol. Geriatr. Res. 2012:359–369.
  • Pincus, Z., Smith-Vikos, T., Slack, F. J. (2011). MicroRNA predictors of longevity in Caenorhabditis elegans. PLoS Genet 7:e1002306.
  • Shaw, A. C., Joshi, S., Greenwood, H., Panda, A., Lord, J. M. (2010). Aging of the innate immune system. Curr. Opin. Immunol. 22:507–513.
  • Smith-Vikos, T., Slack, F. J. (2012). MicroRNAs and their roles in aging. J. Cell Sci. 125:7–17.
  • Tesar, B. M., Walker, W. E., Unternaehrer, J., Joshi, N. S., Chandele, A., Haynes, L., Kaech, S., Goldstein, D. R. (2006). Murine myeloid dendritic cell-dependent toll-like receptor immunity is preserved with aging. Aging Cell 5:473–486.
  • Turner, M. L., Schnorfeil, F. M., Brocker, T. (2011). MicroRNAs regulate dendritic cell differentiation and function. J. Immunol. 187:3911–3917.
  • Wu, M. H., Lee, Y. C., Tsai, W. J., Yang, W. B., Chen, Y. C., Chuang, K. A., Liao, J. F., Wang, C. C., Kuo, Y. C. (2011). Characterized polysaccharides from black soybean induce granulocyte colony-stimulated factor gene expression in a phosphoinositide 3-kinase-dependent manner. Immunol. Invest. 40:39–61.

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