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Immunological Investigations
A Journal of Molecular and Cellular Immunology
Volume 42, 2013 - Issue 6
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Original Article

Interleukin-4, interleukin-4 receptor, and interleukin-18 polymorphisms and rheumatoid arthritis: a meta-analysis

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Pages 455-469 | Received 12 Apr 2013, Accepted 07 May 2013, Published online: 24 Jul 2013

References

  • Amerio P, Frezzolini A, Abeni D, et al. (2002). Increased IL-18 in patients with systemic lupus erythematosus: relations with Th-1, Th-2, pro-inflammatory cytokines and disease activity. IL-18 is a marker of disease activity but does not correlate with pro-inflammatory cytokines. Clin Exper Rheumatol, 20, 535–8
  • Arman A, Coker A, Sarioz O, Inanc N, Direskeneli H. (2011). Lack of association between IL-6 gene polymorphisms and rheumatoid arthritis in Turkish population. Rheumatol Int, Jul 22, 2011 [Epub ahead of print] http://dx.doi.org/10.1007/s00296-011-2057-x
  • Blankenstein T, Volk HD, Techert-Jendrusch C, et al. (1989). Lack of correlation between BglII RFLP in the human interleukin 6 gene and rheumatoid arthritis. Nucl Acids Res, 17, 8902
  • Boraschi D, Dinarello CA. (2006). IL-18 in autoimmunity: review. Euro Cytokine Netw, 17, 224–52
  • Cantagrel A, Navaux F, Loubet-Lescoulie P, et al. (1999). Interleukin-1beta, interleukin-1 receptor antagonist, interleukin-4, and interleukin-10 gene polymorphisms: relationship to occurrence and severity of rheumatoid arthritis. Arthritis Rheumatol, 42, 1093–1100
  • Choi SJ, Rho YH, Ji JD, et al. (2006). Genome scan meta-analysis of rheumatoid arthritis. Rheumatology (Oxford), 45, 166–70
  • Crilly A, Bartlett JM, White A, et al. (2001). Investigation of novel polymorphisms within the 3' region of the IL-6 gene in patients with rheumatoid arthritis using Genescan analysis. Cytokine, 13, 109–12
  • Davey Smith G, Egger M. (1997). Meta-analyses of randomised controlled trials. Lancet, 350, 1182
  • DerSimonian R, Laird N. (1986). Meta-analysis in clinical trials. Control Clin Trials, 7, 177–88
  • Egger M, Davey Smith G, Schneider M, Minder C. (1997). Bias in meta-analysis detected by a simple, graphical test. BMJ, 315, 629–34
  • Fishman D, Faulds G, Jeffery R, et al. (1998). The effect of novel polymorphisms in the interleukin-6 (IL-6) gene on IL-6 transcription and plasma IL-6 levels, and an association with systemic-onset juvenile chronic arthritis. J Clin Invest, 102, 1369–76
  • Fugger L, Morling N, Bendtzen K, et al. (1989). IL-6 gene polymorphism in rheumatoid arthritis, pauciarticular juvenile rheumatoid arthritis, systemic lupus erythematosus, and in healthy Danes. J Immunogenet, 16, 461–5
  • Genevay S, Di Giovine FS, Perneger TV, et al. (2002). Association of interleukin-4 and interleukin-1B gene variants with Larsen score progression in rheumatoid arthritis. Arthritis Rheum, 47, 303–9
  • Giedraitis V, He B, Huang WX, Hillert J. (2001). Cloning and mutation analysis of the human IL-18 promoter: a possible role of polymorphisms in expression regulation. J Neuroimmunol, 112, 146–52
  • Haus-Seuffert P, Meisterernst M. (2000). Mechanisms of transcriptional activation of cAMP-responsive element-binding protein CREB. Mol Cell Biochem, 212, 5–9
  • Higgins JP, Thompson SG. (2002). Quantifying heterogeneity in a meta-analysis. Stat Med, 21, 1539–58
  • Huang XZ, Zhuang JH, Ren YG, et al. (2007). [Association of interleukin-6 and interleukin-18 gene polymorphism with rheumatoid arthritis in Guangdong Han population]. Nan fang yi ke da xue xue bao = J South Med Univ, 27, 1661–4
  • Hussein Y, El-Tarhouny S, Mohamed R, et al. (2012). Association of interleukin-4 receptor gene polymorphisms with rheumatoid arthritis in Egyptian female patients. Joint, Bone, Spine: Revue du Rhumatisme 79, 38–42
  • Lee YH, Rho YH, Choi SJ, et al. (2006). Association of TNF-alpha -308 G/A polymorphism with responsiveness to TNF-alpha-blockers in rheumatoid arthritis: a meta-analysis. Rheumatol Inter, 27, 157–61
  • Lee YH, Witte T, Momot T, et al. (2005). The mannose-binding lectin gene polymorphisms and systemic lupus erythematosus: two case-control studies and a meta-analysis. Arthritis Rheum, 52, 3966–74
  • Li Y, Guo B, Zhang L, et al. (2008). Association between C-589T polymorphisms of interleukin-4 gene promoter and asthma: a meta-analysis. Respir Med, 102, 984–92
  • Li B, Tournier C, Davis RJ, Flavell RA. (1999). Regulation of IL-4 expression by the transcription factor JunB during T helper cell differentiation. EMBO J, 18, 420–32
  • Lo SF, Huang CM, Lin HC, et al. (2008). Cytokine (IL-6) and chemokine (IL-8) gene polymorphisms among rheumatoid arthritis patients in Taiwan. Clin Exper Rheumatol, 26, 632–7
  • Lopez-Mejias R, Garcia-Bermudez M, Gonzalez-Juanatey C, et al. (2011). Lack of association between IL6 single nucleotide polymorphisms and cardiovascular disease in Spanish patients with rheumatoid arthritis. Atherosclerosis, 219, 655–8
  • Marinou I, Till SH, Moore DJ, Wilson AG. (2008). Lack of association or interactions between the IL-4, IL-4Ralpha and IL-13 genes, and rheumatoid arthritis. Arthritis Res Ther, 10, 1–7
  • Martinez A, Pascual M, Pascual-Salcedo D, et al. (2003). Genetic polymorphisms in Spanish rheumatoid arthritis patients: an association and linkage study. Genes Immun, 4, 117–21
  • Mirel DB, Barcellos LF, Wang J, et al. (2004). Analysis of IL4R haplotypes in predisposition to multiple sclerosis. Genes Immun, 5, 138–41
  • Moreno O, Gonzalez CI, Saaibi DL, et al. (2007). Polymorphisms in the IL4 and IL4RA genes in Colombian patients with rheumatoid arthritis. J Rheumatol, 34, 36–42
  • Morita Y, Yamamura M, Kawashima M, et al. (2001). Differential in vitro effects of IL-4, IL-10, and IL-13 on proinflammatory cytokine production and fibroblast proliferation in rheumatoid synovium. Rheumatol Inter, 20, 49–54
  • Nath SK, Harley JB, Lee YH. (2005). Polymorphisms of complement receptor 1 and interleukin-10 genes and systemic lupus erythematosus: a meta-analysis. Human Genetics, 118, 225–34
  • Nelms K, Keegan AD, Zamorano J, et al. (1999). The IL-4 receptor: signaling mechanisms and biologic functions. Ann Rev Immunol, 17, 701–38
  • Nolan KF, Greaves DR, Waldmann H. (1998). The human interleukin 18 gene IL18 maps to 11q22.2-q22.3, closely linked to the DRD2 gene locus and distinct from mapped IDDM loci. Genomics, 51, 161–3
  • Nunez C, Santiago JL, Varade J, et al. (2008). IL4 in the 5q31 context: association studies of type 1 diabetes and rheumatoid arthritis in the Spanish population. Immunogenetics, 60, 19–23
  • Palomino-Morales R, Gonzalez-Juanatey C, Vazquez-Rodriguez TR, et al. (2009). Interleukin-6 gene -174 promoter polymorphism is associated with endothelial dysfunction but not with disease susceptibility in patients with rheumatoid arthritis. Clin Exper Rheumatol, 27, 964–70
  • Panoulas VF, Stavropoulos-Kalinoglou A, Metsios GS, et al. (2009). Association of interleukin-6 (IL-6)-174G/C gene polymorphism with cardiovascular disease in patients with rheumatoid arthritis: the role of obesity and smoking. Atherosclerosis, 204, 178–83
  • Pawlik A, Kurzawski M, Czerny B, et al. (2006). Interleukin-18 promoter polymorphism in patients with rheumatoid arthritis. Tissue Antigens, 67, 415–8
  • Pawlik A, Kurzawski M, Drozdzik M, et al. (2009). Interleukin-18 gene (IL18) promoter polymorphisms in patients with rheumatoid arthritis. Scand J Rheumatol, 38, 159–65
  • Pawlik A, Wrzesniewska J, Florczak M, et al. (2005a). The -590 IL-4 promoter polymorphism in patients with rheumatoid arthritis. Rheumatol Inter, 26, 48–51
  • Pawlik A, Wrzesniewska J, Florczak M, et al. (2005b). IL-6 promoter polymorphism in patients with rheumatoid arthritis. Scand J Rheumatol, 34, 109–13
  • Prots I, Skapenko A, Wendler J, et al. (2006). Association of the IL4R single-nucleotide polymorphism I50V with rapidly erosive rheumatoid arthritis. Arthritis Rheum, 54, 1491–500
  • Rosenwasser LJ, Klemm DJ, Dresback JK, et al. (1925). Promoter polymorphisms in the chromosome 5 gene cluster in asthma and atopy. Clin Exper Allergy: J Brit Soc Allergy Clin Immunol, 25 Suppl, 2, 74–8; discussion 95–6
  • Rueda B, Gonzalez-Gay MA, Mataran L, et al. (2005). Interleukin-18-promoter polymorphisms are not relevant in rheumatoid arthritis. Tissue Antigens, 65, 544–8
  • Sivalingam SP, Yoon KH, Koh DR, Fong KY. (2003). Single-nucleotide polymorphisms of the interleukin-18 gene promoter region in rheumatoid arthritis patients: protective effect of AA genotype. Tissue Antigens, 62, 498–504
  • Sugiura T, Kawaguchi Y, Ikari K, et al. (2011). Interleukin-18 promoter polymorphisms in Japanese patients with rheumatoid arthritis: protective effect of the T allele and T/T genotype at rs360722. Mod Rheumatol/Japan Rheum Asso, 21, 359–64
  • Suppiah V, Rooney M, Vandenbroeck K. (2006). Polymorphisms in the interleukin-4 and IL-4 receptor genes modify risk for chronic inflammatory arthropathies in women. Exper Mol Pathol, 81, 239–44
  • Trajkov D, Mishevska-Perchinkova S, Karadzova-Stojanoska A, et al. (2009). Association of 22 cytokine gene polymorphisms with rheumatoid arthritis in population of ethnic Macedonians. Clin Rheumatol, 28, 1291–300
  • Ying B, Shi Y, Pan X, et al. (2011). Association of polymorphisms in the human IL-10 and IL-18 genes with rheumatoid arthritis. Mol Biol Repts, 38, 379–85

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