References
- Chen W, Ford MS, Young KJ, et al. (2003). Role of double-negative regulatory T cells in long-term cardiac xenograft survival. J Immunol, 170, 1846–53
- Chen W, Zhou D, Torrealba JR, et al. (2005). Donor lymphocyte infusion induces long-term donor-specific cardiac xenograft survival through activation of recipient double-negative regulatory T cells. J Immunol, 175, 3409–16
- Cheney KM, Kumar R, Purins A, et al. (2006). HIV type 1 persistence in CD4- /CD8- double negative T cells from patients on antiretroviral therapy. AIDS Res Hum Retroviruses, 22, 66–75
- Cowley SC, Meierovics AI, Frelinger JA, et al. (2010). Lung CD4-CD8- double-negative T cells are prominent producers of IL-17A and IFN-gamma during primary respiratory murine infection with Francisella tularensis live vaccine strain. J Immunol, 184, 5791–801
- D'Acquisto F, Crompton T. (2011). CD3+CD4-CD8- (double negative) T cells: saviours or villains of the immune response? Biochem Pharmacol, 82, 333–40
- Fiebig EW, Wright DJ, Rawal BD, et al. (2003). Dynamics of HIV viremia and antibody seroconversion in plasma donors: implications for diagnosis and staging of primary HIV infection. AIDS, 17, 1871–9
- Fischer K, Voelkl S, Heymann J, et al. (2005). Isolation and characterization of human antigen-specific TCR alpha beta+ CD4(-)CD8- double-negative regulatory T cells. Blood, 105, 2828–35
- Ford MS, Young KJ, Zhang Z, et al. (2002). The immune regulatory function of lymphoproliferative double negative T cells in vitro and in vivo. J Exp Med, 196, 261–7
- Jiao Y, Song Y, Kou B, et al. (2012a). Primary CXCR4 co-receptor use in acute HIV infection leads to rapid disease progression in the AE subtype. Viral Immunol, 25, 262–7
- Jiao Y, Zhang T, Wang R, et al. (2012b). Plasma IP-10 is associated with rapid disease progression in early HIV-1 infection. Viral Immunol, 25, 333–7
- Kaiser P, Joos B, Niederost B, et al. (2007). Productive human immunodeficiency virus type 1 infection in peripheral blood predominantly takes place in CD4/CD8 double-negative T lymphocytes. J Virol, 81, 9693–706
- Ma Y, He KM, Garcia B, et al. (2008). Adoptive transfer of double negative T regulatory cells induces B-cell death in vivo and alters rejection pattern of rat-to-mouse heart transplantation. Xenotransplantation, 15, 56–63
- Marodon G, Warren D, Filomio MC, Posnett DN. (1999). Productive infection of double-negative T cells with HIV in vivo. Proc Natl Acad Sci USA, 96, 11958–63
- Milush JM, Mir KD, Sundaravaradan V, et al. (2011). Lack of clinical AIDS in SIV-infected sooty mangabeys with significant CD4+ T cell loss is associated with double-negative T cells. J Clin Invest, 121, 1102–110
- Petitjean G, Chevalier MF, Tibaoui F, et al. (2012). Level of double negative T cells, which produce TGF-beta and IL-10, predicts CD8 T-cell activation in primary HIV-1 infection. AIDS, 26, 139–48
- Restrepo C, Rallón NI, del Romero J, et al. (2013). HIV Gag-specific immune response mediated by double negative (CD3(+)CD4(−)CD8(−)) T cells in HIV-exposed seronegative individuals. J Med Virol, 85, 200–9
- Sundaravaradan V, Mir KD, Sodora DL. (2012). Double-negative T cells during HIV/SIV infections: potential pinch hitters in the T-cell lineup. Curr Opin HIV AIDS, 7, 164–71
- Suzuki H. (2009). Differences in intraepithelial lymphocytes in the proximal, middle, distal parts of small intestine, cecum, and colon of mice. Immunol Invest, 38, 780–796
- Thomson CW, Lee BP, Zhang L. (2006). Double-negative regulatory T cells: non-conventional regulators. Immunol Res, 35, 163–78
- Villani FN, Rocha MO, Nunes Mdo C, et al. (2010). Trypanosoma cruzi-induced activation of functionally distinct alphabeta and gammadelta CD4- CD8- T cells in individuals with polar forms of Chagas' disease. Infect Immun, 78, 4421–30
- Vinton C, Klatt NR, Harris LD, et al. (2011). CD4-like immunological function by CD4- T cells in multiple natural hosts of simian immunodeficiency virus. J Virol, 85, 8702–8
- Voelkl S, Gary R, Mackensen A. (2011). Characterization of the immunoregulatory function of human TCR-alphabeta+ CD4- CD8- double-negative T cells. Eur J Immunol, 41, 739–48
- Voelkl S, Moore TV, Rehli M, et al. (2009). Characterization of MHC class-I restricted TCRalphabeta+ CD4- CD8- double negative T cells recognizing the gp100 antigen from a melanoma patient after gp100 vaccination. Cancer Immunol Immunother, 58, 709–18
- Xing Q, Su H, Cui J, Wang B. (2012). Role of Treg cells and TGF-β1 in patients with systemic lupus erythematosus: a possible relation with lupus nephritis. Immunol Invest, 41, 15–27
- Young KJ, Yang L, Phillips MJ, Zhang L. (2002). Donor-lymphocyte infusion induces transplantation tolerance by activating systemic and graft-infiltrating double-negative regulatory T cells. Blood, 100, 3408–14
- Zhang ZX, Ma Y, Wang H, et al. (2006). Double-negative T cells, activated by xenoantigen, lyse autologous B and T cells using a perforin/granzyme-dependent, Fas-Fas ligand-independent pathway. J Immunol, 177, 6920–9
- Zhang ZX, Yang L, Young KJ, et al. (2000). Identification of a previously unknown antigen-specific regulatory T cell and its mechanism of suppression. Nat Med, 6, 782–9
- Zhang ZX, Young K, Zhang L. (2001). CD3+CD4-CD8- alphabeta-TCR+ T cell as immune regulatory cell. J Mol Med (Berl), 79, 419–27