Prevention of Renal Injury and Endothelial Dysfunction by Chronic l-Arginine and Antioxidant Treatment

References

• Persson PB. Nitric oxide in the kidney. Am J Physiol regul Integr Comp Physiol. 2002;283:R1005–R1007.
   Web of Science ®Google Scholar
• Mattson DL, Lu S, Nakanishi K, Papanek PE, Cowley AW, Jr. Effects of chronic renal medullary nitric oxide inhibition on blood pressure. Am J Physyiol. 1994;266:H1918–H1926.
   PubMed Web of Science ®Google Scholar
• Aiello S, Noris M, Todeschini M, Renal and systemic nitric oxide in rats with renal mass reduction. Kidney Int. 1997;52:171–181.
   PubMed Web of Science ®Google Scholar
• Conger J, Robinnette J, Villar A. Increased nitric oxide synthase activity despite lack of response to endothelium-dependent vasodilatation in post ischemic acute renal failure in rats. J Clin Invest. 1995;96:631–638.
   PubMed Web of Science ®Google Scholar
• Baylis C. Nitric oxide deficiency in chronic kidney disease. Am J Physiol. 2008;294:F1–F9.
   PubMed Web of Science ®Google Scholar
• Arellano Mendoza MG, Castillo Henkel C, Medina Santillan R Kidney damage after renal ablation is worsened in endothelial nitric oxide synthase (-/-) mice and improved by combined administration of l-Arginine and antioxidants. Nephrology. 2008;13:218–227.
   Google Scholar
• Mimic-Oka J, Simic T, Djukanovic L. Alteration in plasma antioxidant capacity in various degree of chronic renal failure. Clin Nephrol. 1999;51:233–241.
   PubMed Web of Science ®Google Scholar
• Tain YL, Freshour G, Dikalova A, Griendling K, Baylis, C. Vitamin E reduces glomerulosclerosis, restores renal neuronal NOS and suppresses oxidative stress in the 5/6 nephrectomized rat. Am J Physiol Renal Physiol. 2007;292:F1404–F1410.
   PubMed Web of Science ®Google Scholar
• Hasdan G, Benchetrit S, Rashid G, Green J, Bernheim J, Rathaus M. Endothelial dysfunction and hypertension in 5/6 nephrectomized rats are mediated by vascular superoxide. Kidney Int. 2002;61:586–590.
   Google Scholar
• Modlinger PS, Wilcox CS, Aslam S. Nitric oxide, oxidative stress and progression of chronic renal failure. Semin Nephrol. 2004;24:354–365.
   PubMed Web of Science ®Google Scholar
• Katoh T, Takohashi K, Klahr S, Reyes AA, Badr KF. Dietary supplementation with l-arginine ameliorates glomerular hypertension in rats with subtotal nephrectomy. J Am Soc Nephrol. 1994;4:1690–1694.
   Google Scholar
• Reyes AA, Karl IE, Kissane J, Klahr S. L-arginine administration prevents glomerular hyperfiltration and decreases proteinuria in diabetic rats. J Am Soc Nephrol. 1993;4: 1039–1045.
   PubMedGoogle Scholar
• De Nicola L, Thomson SC, Wead LM, Brown MR, Gabbai FB. Arginine feeding modifies cyclosporine nephrotoxicity in rats. J Clin Invest. 1993;92:1859–1865.
   PubMed Web of Science ®Google Scholar
• Kashihara N, Satoh M. Molecular pathogenesis of chronic kidney disease. Nippon Rinsho. 2008;66:1671–1677.
   Google Scholar
• Sucher R, Gehwolf P, Oberhuber R, Tetrahydrobiopterin protects the kidney from ischemia reperfusion injury. Kidney Int. 2010;77:681–689. Epub 2010 Feb 17.
   Google Scholar
• Yamamizu K, Shinozozaki K, Ayajiki K, Gemba M, Okamura T. Oral administration of both tetrahydrobiopterin and l-arginine prevents endothelial dysfunction in rats with chronic renal failure. J Cardiovscular Pharmacol. 2007;49:131–139.
   PubMedGoogle Scholar
• Korish AA. Oxidative stress and nitric oxide deficiency in inflammation of chronic renal failure. Possible preventive role of l-arginine and multiple antioxidants. Saudi Med J. 2009;30: 1150–1157.
   PubMed Web of Science ®Google Scholar
• Wuhl E, Schaefer F. Therapeutic strategies to slow chronic kidney disease progression. Pediatr Nephrol. 2008;23:705–716.
   PubMed Web of Science ®Google Scholar
• Coronel I, Arellano-Mendoza MG, Del Valle-Mondragon L, et al. l-arginine and antioxidant diet supplementation partially restores nitric oxide dependent regulation of phenylephrine renal vasoconstriction in diabetic rats. J Ren Nutr. 2010;20: 158–168.
   Google Scholar
• Griffin KA, Picken M, Bidani AK. Method of renal mass reduction is a critical modulator of subsequent injury and hypertension. J Am Soc Nephrol. 1994;4:2023–2031.
   PubMed Web of Science ®Google Scholar
• Bradford MM. A rapid and sensitive method for the quantization of microgram quantities of protein utilizing the principle of protein dye binding. Ann Biochem. 1976;72:248–254.
   Web of Science ®Google Scholar
• Han F, Huynh BH, Shi H, Lin B, Ma Y. Pteridine analysis in urine by capillary electrophoresis using laser-induced fluorescence detection. Anal Chem. 1999;71:1265–1269.
   PubMed Web of Science ®Google Scholar
• Livak KJ, Schmittgen TD. Analysis of relative gene expression real-time quantitative PCR and the 2(-Delta Delta C (T)) Method. Methods. 2001;25:402–408.
   PubMed Web of Science ®Google Scholar
• Miller FJ, Jr, Gulterman DD, Rios CD, Heistad DD, Davidson BL. Superoxide production in vascular smooth muscle contributes to oxidative stress and impaired relaxation in atherosclerosis. Circ Res. 1998;82:1298–1305.
   PubMed Web of Science ®Google Scholar
• Rothe G, Valet G. Flow cytometric analysis of respiratory bursa activity in phagocytes whit hydroethidium and 2′,7′dichlorofluorescein. J Leukoc Biol. 1995;55:253–258.
   Google Scholar
• Van Dokkum RP, Jacob HJ, Provoost AP. Genetic differences define severity of renal damage after l-NAME induced hypertension in rats. J Am Soc Neprhol. 1998;9:363–371.
   Google Scholar
• Robertso JL, Goldschmidt M, Kronfeld DS, Tomaszewski JE, Hill GS, Bovee KC. Long-term renal responses to high dietary protein in dogs with 75% nephrectomy. Kidney Int. 1986; 29:511–519.
   Google Scholar
• Wuhl E, Schaefer F. Can we slow the progression of chronic kidney disease? Curr Opin Pediatr. 2010;22:170–175.
   Google Scholar
• Ashab I, Peer G, Blum M, Oral administration of l-arginine and captopril in rats prevents chronic renal failure by nitric oxide production. Kidney Int. 1995;47:1515–1521.
   PubMed Web of Science ®Google Scholar
• Huang A, Vita JA, Venema RC, Keaney JF, Jr. Ascorbic acid enhances endothelial nitric oxide synthase activity by increasing intracellular tetrahydrobiopterin. J Biol Chem. 2000;275: 17399–17406.
   PubMed Web of Science ®Google Scholar
• Baker TA, Milstien S, Katsic ZS. Effect of vitamin C on the availability of tetrahydrobiopterin in human endothelial cells. J Cardiovasc Pharmacol. 2001;37:333–338.
   PubMed Web of Science ®Google Scholar
• Okon EB, Chung AWY, Rauniyar P, Compromised arterial function in human type 2 diabetic patients. Diabetes. 2005;54:2415–2423.
   Google Scholar
• Guzik TJ, Mussa S, Gastaldi D, Mechanism of increased vascular superoxide production in human diabetes mellitus: role of NADPH oxidase and endothelial nitric oxide synthase. Circulation. 2002;105:1656–1662.
   PubMed Web of Science ®Google Scholar
• Settergreen M, Bohn F, Malmstrom RE, Channon KM, Pemow J. l-arginine and tetrahydrobiopterin protects against ischemia/reperfusion-induced endothelial dysfunction in patients with type 2 diabetes mellitus and coronary artery disease. Atherosclerosis. 2009;204:73–78.
   Google Scholar