REFERENCES
- Najmabadi H, Ghamari A, Sahebjam F, . Fourteen-year experience of prenatal diagnosis of thalassemia in Iran. Community Genet. 2006;9:93–97.
- Samavat A, Modell B. Iranian national thalassemia screening programme. BMJ. 2004;329:1134–1137.
- Gohari LH, Petrou M, Felekis X, . Identification of α-thalassemia mutations in iranian individuals with abnormal hematological indices and normal Hb A2. Hemoglobin. 2003;27:129–132.
- Garshasbi M, Oberkanins C, Law HY, . α-Globin gene deletion and point mutation analysis among Iranian patients with microcytic hypochromic anemia. Haematologica. 2003;88:1196– 1197.
- Yavarian M, Karimi M, Zorai A, . Molecular basis of Hb H disease in southwest Iran. Hemoglobin. 2005;29:43–50.
- Hadavi V, Taromchi AH, Malekpour M, . Elucidating the spectrum of α-thalassemia mutations in Iran. Haematologica. 2007;92:992–993.
- Zandian Kh, Nateghi J, Keikhahi B, . α Thalassemia mutation in Khuzestan province, South west Iran. Hemoglobin. 2008;32:546–552.
- Neishaboury M, Azarkeivan A, Oberkanins C, . Molecular mechanisms underlying thalassemia intermedia in Iran. Genet Test. 2008;12:549–556.
- Harteveld CL, Yavarian M, Zorai A, . Molecular spectrum of alpha-thalassemia in the Iranian population of Hormozgan: three novel point mutation defects. Am J Hematol. 2003;74:99–103.
- Neishabury M, Oberkanins C, Moheb LA, . High prevalence of the −alpha3.7 deletion among thalassemia patients in Iran. Hemoglobin. 2003;27:53–55.
- Tamaddoni A, Hadavi V, Nejad NH, . Alpha thalassemia analyses in Mazandaran province, North Iran. Hemoglobin. 2009;33:115–123.
- Weatherall DJ. Phenotype–genotype relations in monogenic diseases; lessen from the thalassemia. Nat Genet. 2001;2:245–255.
- Birgens H, Ljung R. The thalassaemia syndromes. Scand J Clin Lab Invest. 2007;67:11–25.
- Higgs DR, Weatherall DJ. The alpha thalassaemias. Cell Mol Life Sci. 2009;66:1154–1162.
- Kan YW. Molecular pathology of α-thalassemia. Ann N Y Acad Sci. 1985;445:28–36.
- Chui DH, Fucharoen S, Chan V. Hemoglobin H disease: not necessarily a benign disorder. Blood. 2003;101:791–800.
- Puehringer H, Najmabadi H, Law HY, . Validation of a reverse-hybridization StripAssay for simultaneous analysis of common alpha-thalassemia point mutations and deletions. Clin Chem Lab Med. 2007;45:605–610.
- Miller SA, Dykes DD, Polesky HF. A simple salting out procedure for extracting DNA from human nucleated cells. Nucleic Acids Res. 1988;16:1215.
- Oron-Karni V, Filon D, Oppenheim A, Rund D. Rapid detection of the common Mediterranean alpha-globin deletions/rearrangements using PCR. Am J Hematol. 1998;58:306–310.
- Baysal E, Huisman TH. Detection of common deletional alpha-thalassemia-2 determinants by PCR. Am J Hematol. 1994;46:208–213.
- Kanavakis E, Papassotiriou I, Karagiorga M, . Phenotypic and molecular diversity of hemoglobin H disease: a Greek experience. Br J Haematol. 2000;111:915–923.
- Chen FE, Ooi C, Ha SY, . Genetic and clinical features of hemoglobin H disease in Chinese patients. N Engl J Med. 2000;343:544–550.
- Lau YL, Chan LC, Chan YY, . Prevalence and genotypes of α- and β-thalassemia carriers in Hong Kong—implications for population screening. N Engl J Med. 1997;336:1298–1301.
- Winichagoon P, Higgs DR, Goodbourn SE, . The molecular basis of alpha-thalassaemia in Thailand. EMBO J. 1984; 3:1813–1818.
- Lorey F, Cunningham G, Vichinsky EP, . Universal newborn screening for Hb H disease in California. Genet Test. 2001;5:93–100.
- Baysal E, Kleanthous M, Bozkurt G, . α-Thalassaemia in the population of Cyprus. Br J Haematol. 1995; 89:496–499.
- Higgs DR, Vickers MA, Wilkie AO, . A review of the molecular genetics of the human alpha-globin gene cluster. Blood. 1989;73:1081–1084.
- Old JM. Screening and genetic diagnosis of haemoglobinopathies. Scand J Clin Lab Invest. 2007 67:71–86.
- Higgs DR, Pressley L, Aldridge B, . Genetic and molecular diversity in nondeletion Hb H disease. Proc Natl Acad Sci U S A. 1981;78:5833–5837.
- Thein SL. Genetic modifiers of the beta-haemoglobinopathies. Br J Haematol. 2008;141:357–366.