In-Vitro Platelet Hyperaggregation and Hypersecretion Associated with the Use of Fish Oil in Healthy Children

REFERENCES

• Guilliams TG. The use of fish oil supplements in clinical practice: a review. JANA. 2005;1:21–34.
   Google Scholar
• Harris WS. Fish oil supplementation: evidence for health benefits. Cleve Clin J Med. 2004;71:208–210.
   PubMed Web of Science ®Google Scholar
• Harris WS, Reid KJ, Sands SA, Spertus JA. Blood omega-3 and trans fatty acids in middle-aged acute coronary syndrome patients. Am J Cardiol. 2007;99:154–158.
   PubMed Web of Science ®Google Scholar
• Geelen A, Brouwer IA, Schouten EG, et al. Effects of n-3 fatty acids from fish on premature ventricular complexes and heart rate in humans. Am J Clin Nutr. 2005;81:416–420.
   PubMed Web of Science ®Google Scholar
• Leaf A, Albert CM, Josephson M, et al. Prevention of fatal arrhythmias in high-risk subjects by fish oil n-3 fatty acid intake. Circulation. 2005;112:2762–2768.
   PubMed Web of Science ®Google Scholar
• von Schacky C, Angerer P, Kothny W, et al. The effect of dietary omega-3 fatty acids on coronary atherosclerosis. A randomized, double-blind, placebo-controlled trial. Ann Intern Med. 1999;130:554–562.
   PubMed Web of Science ®Google Scholar
• Gapinski JP, VanRuiswyk JV, Heudebert GR, Schectman. Preventing restenosis with fish oils following coronary angioplasty. A meta-analysis. Arch Intern Med. 1993;153:1595–1601.
   PubMedGoogle Scholar
• Erkkilä AT, Lichtenstein AH, Mozaffarian D, Herrington DM. Fish intake is associated with a reduced progression of coronary artery atherosclerosis in postmenopausal women with coronary artery disease. Am J Clin Nutr. 2004;80:626–632.
   PubMed Web of Science ®Google Scholar
• Dallongeville J, Yarnell J, Ducimetière P, et al. Fish consumption is associated with lower heart rates. Circulation. 2003;108:820–825.
   PubMed Web of Science ®Google Scholar
• Lovegrove JA, Lovegrove SS, Lesauvage SV, Moderate fish-oil supplementation reverses low-platelet, long-chain n-3 polyunsaturated fatty acid status and reduces plasma triacylglycerol concentrations in British Indo-Asians. Am J Clin Nutr. 2004;79:974–982.
   PubMed Web of Science ®Google Scholar
• Appel LJ, Miller ER III, Seidler AJ, Whelton PK. Does supplementation of diet with “fish oil” reduce blood pressure? A meta-analysis of controlled clinical trials. Arch Intern Med. 1993;153:1429–1438.
   PubMed Web of Science ®Google Scholar
• Toft I, Bønaa KH, Ingebretsen OC, et al. Effects of n-3 polyunsaturated fatty acids on glucose homeostasis and blood pressure in essential hypertension. A randomized, controlled trial. Ann Intern Med. 1995;123:911–918.
   PubMed Web of Science ®Google Scholar
• Esposito K, Marfella R, Ciotola M, et al. Effect of a Mediterranean-style diet on endothelial dysfunction and markers of vascular inflammation in the metabolic syndrome: a randomized trial. JAMA. 2004;292:1440–1446.
   PubMed Web of Science ®Google Scholar
• Kabir M, Skurnik G, Naour N, et al. Treatment for 2 mo with n-3 polyunsaturated fatty acids reduces adiposity and some atherogenic factors but does not improve insulin sensitivity in women with type 2 diabetes: a randomized controlled study. Am J Clin Nutr. 2007;86:1670–1679.
   PubMed Web of Science ®Google Scholar
• Mori TA, Bao DQ, Burke V, et al. Dietary fish as a major component of a weight-loss diet: effect on serum lipids, glucose, and insulin metabolism in overweight hypertensive subjects. Am J Clin Nutr. 1999;70:817–825.
   PubMed Web of Science ®Google Scholar
• Galarraga B, Ho M, Youssef HM, et al. Cod liver oil (n-3 fatty acids) as an nonsteroidal anti-inflammatory drug sparing agent in rheumatoid arthritis. Rheumatology (Oxford). 2008;47: 665–669.
   PubMed Web of Science ®Google Scholar
• Geusens P, Wouters C, Nijs J, et al. Long-term effect of omega-3 fatty acid supplementation in active rheumatoid arthritis. A 12-month, double-blind, controlled study. Arthritis Rheum. 1994;37:824–829.
   PubMed Web of Science ®Google Scholar
• Belluzzi A, Brignola C, Campieri M, et al. Effect of an enteric-coated fish-oil preparation on relapses in Crohn's disease. N Engl J Med. 1996;334:1557–1560.
   PubMed Web of Science ®Google Scholar
• Schaefer EJ, Bongard V, Beiser AS, Plasma phosphatidylcholine docosahexaenoic acid content and risk of dementia and Alzheimer disease: the Framingham Heart Study. Arch Neurol. 2006;63:1545–1550.
   PubMed Web of Science ®Google Scholar
• Hamazaki T, Sawazaki S, Itomura M, The effect of docosahexaenoic acid on aggression in young adults. A placebo-controlled double-blind study. J Clin Invest. 1996;97:1129–1133.
   PubMed Web of Science ®Google Scholar
• Chong EW, Kreis AJ, Wong TY, et al. Dietary omega-3 fatty acid and fish intake in the primary prevention of age-related macular degeneration: a systematic review and meta-analysis. Arch Ophthalmol. 2008;126:826–833.
   PubMedGoogle Scholar
• Weiss LA, Barrett-Connor E, von Mühlen D. Ratio of n-6 to n-3 fatty acids and bone mineral density in older adults: the Rancho Bernardo Study. Am J Clin Nutr. 2005;81:934–938.
   PubMed Web of Science ®Google Scholar
• Hogg RJ, Fitzgibbons L, Atkins C, et al. Efficacy of omega-3 fatty acids in children and adults with IgA nephropathy is dosage- and size-dependent. Clin J Am Soc Nephrol. 2006;1:1167–1172.
   PubMed Web of Science ®Google Scholar
• Kris-Etherton PM, Harris WS, Appel LJ; Nutrition Committee. Fish consumption, fish oil, omega-3 fatty acids, and cardiovascular disease. Arterioscler Thromb Vasc Biol. 2003;23:151–152.
   PubMed Web of Science ®Google Scholar
• Mackay I, Ford I, Thies F, Effect of omega-3 fatty acid supplementation on markers of platelet and endothelial function in patients with peripheral arterial disease. Atherosclerosis. 2012;221:514–520.
   PubMed Web of Science ®Google Scholar
• Opperman M, Marais de W, Spinnler Benade AJ. Analysis of omega-3 fatty acid content of South African fish oil supplements. Cardiovasc J Afr. 2011;22:324–329.
   PubMed Web of Science ®Google Scholar
• Woodside JV, Kromhout D. Fatty acids and CHD. Proc Nutr Soc. 2005;64:554–564.
   PubMed Web of Science ®Google Scholar
• Akça T, Karagöz T. Omega-3 yağ asitleri ve kalp hastalıkları. Katkı. 2006;28:78–88.
   Google Scholar
• Agren JJ, Vaisanen S, Hanninen O, Hemostatic factors and platelet aggregation after a fish-enriched diet or fish oil or docosahexaenoic acid supplementation. Prostaglandins Leukot Essent Fatty Acids. 1997;57:419–421.
   PubMed Web of Science ®Google Scholar
• Mori TA, Beilin LJ, Burke V, Interactions between dietary fat, fish, and fish oils and their effects on platelet function in men at risk of cardiovascular disease. Arterioscler Thromb Vasc Biol. 1997;17:279–286.
   PubMed Web of Science ®Google Scholar
• Vanschoonbeek K, de Maat MP, Heemskerk JW. Fish oil consumption and reduction of arterial disease. J Nutr. 2003;133:657–658.
   PubMed Web of Science ®Google Scholar
• Malle E, Kostner GM. Effects of fish oil on lipid variables and platelet function indices. Prostaglandins Leukot Essent Fatty Acids. 1993;49:645–663.
   PubMed Web of Science ®Google Scholar
• Saremi A, Arora R. The utility of omega-3 fatty acids in cardiovascular disease. Am J Ther. 2009;16:421–436.
   PubMed Web of Science ®Google Scholar
• Salachas A, Papadopoulos C, Sakadamis G, Effects of a low-dose fish oil concentrate on angina, exercise tolerance time, serum triglycerides, and platelet function. Angiology. 1994;45:1023–1031.
   PubMed Web of Science ®Google Scholar
• Phang M, Sinclair AJ, Lincz LF, Garg ML. Gender-specific inhibition of platelet aggregation following omega-3 fatty acid supplementation. Nutr Metab Cardiovasc Dis. 2012;22:109–114.
   PubMed Web of Science ®Google Scholar
• von Schacky C, Weber PC. Metabolism and effects on platelet function of the purified eicosapentaenoic and docosahexaenoic acids in humans. J Clin Invest. 1985;76:2446–2450.
   PubMed Web of Science ®Google Scholar
• Larson MK, Ashmore JH, Harris KA, Effects of omega-3 acid ethyl esters and aspirin, alone and in combination, on platelet function in healthy subjects. Thromb Haemost. 2008;100:634–641.
   PubMed Web of Science ®Google Scholar
• Guillot N, Caillet E, Laville M, Increasing intakes of the long-chain omega-3 docosahexaenoic acid: effects on platelet functions and redox status in healthy men. FASEB J. 2009;23:2909–2916.
   PubMed Web of Science ®Google Scholar
• Mackay I, Ford I, Thies F, et al. Effect of omega-3 fatty acid supplementation on markers of platelet and endothelial function in patients with peripheral arterial disease. Atherosclerosis. 2012;221:514–520.
   PubMed Web of Science ®Google Scholar
• Shahar E, Folsom AR, Wu KK, Associations of fish intake and dietary n-3 polyunsaturated fatty acids with a hypocoagulable profile. The Atherosclerosis Risk In Communities (ARIC) Study. Arterioscler Thromb. 1993;13:1205–1212.
   PubMed Web of Science ®Google Scholar
• Archer SL, Green D, Chamberlain M, Association of dietary fish and n-3 fatty acid intake with hemostatic factors in the Coronary Artery Risk Development In Young Adults (CARDIA) Study. Arterioscler Thromb Vasc Biol. 1998;18:1119–1123.
   PubMed Web of Science ®Google Scholar
• Marckmann P, Bladbjerg EM, Jespersen J. Dietary fish oil (4 g daily) and cardiovascular risk markers in healthy men. Arterioscler Thromb Vasc Biol. 1997;17:3384–3391.
   PubMed Web of Science ®Google Scholar
• Johansen O, Seljeflot I, Hostmark AT, Arnesen H. The effect of supplementation with omega-3 fatty acids on soluble markers of endothelial function in patients with coronary heart disease. Arterioscler Thromb Vas Biol. 1999;19:1681–1686.
   PubMed Web of Science ®Google Scholar