Pediatric Survivors of Retinoblastoma Are at Risk for Altered Bone Metabolism After Chemotherapy Treatment Early in Life

REFERENCES

• Oeffinger KC, Mertens AC, Sklar CA, et al. Chronic health conditions in adult survivors of childhood cancer. N Engl J Med. 2006;355:1572–1582.
   PubMed Web of Science ®Google Scholar
• Ness KK, Hudson MM, Ginsberg JP, et al. Physical performance limitations in the Childhood Cancer Survivor Study cohort. J Clin Oncol. 2009;27:2382–2389.
   PubMed Web of Science ®Google Scholar
• Mostoufi-Moab S, Brodsky J, Isaacoff EJ, et al. Longitudinal assessment of bone density and structure in childhood survivors of acute lymphoblastic leukemia without cranial radiation. J Clin Endocrinol Metab. 2012;97:3584–3592.
   PubMed Web of Science ®Google Scholar
• Mäkitie O, Heikkinen R, Toiviainen-Salo S, Henriksson M, Puukko-Viertomies L-R, Jahnukainen K. Long-term skeletal consequences of childhood acute lymphoblastic leukemia in adult males: a cohort study. Eur J Endocrinol. 2013;168:281–288.
   PubMed Web of Science ®Google Scholar
• Mody R, Li S, Dover DC, Sallan S, et al. Twenty-five-year follow-up among survivors of childhood acute lymphoblastic leukemia: a report from the Childhood Cancer Survivor Study. Blood. 2008;111:5515–5523.
   PubMed Web of Science ®Google Scholar
• Kaste SC, Chesney RW, Hudson MM, Lustig RH, Rose SR, Carbone LD. Bone mineral status during and after therapy of childhood cancer: an increasing population with multiple risk factors for impaired bone health. J Bone Miner Res. 1999;14:2010–2014.
   PubMed Web of Science ®Google Scholar
• Den Hoed M, Klap B, teWinkel M, et al. Bone mineral density after childhood cancer in 346 long-term adult survivors of childhood cancer. Osteoporos Int. 2015;26: 521–529.
   PubMed Web of Science ®Google Scholar
• Dimaras H, Kimani K, Dimba EO, et al. Retinoblastoma. Lancet. 2012;379:1436–1446.
   PubMed Web of Science ®Google Scholar
• MacCarthy A, Draper GJ, Steliarova-Foucher E, Kingston JE. Retinoblastoma incidence and survival in European children (1978–1997). Report from the Automated Childhood Cancer Information System project. Eur J Cancer. 2006;42:2092–2102.
   PubMed Web of Science ®Google Scholar
• Van Dijk J, Oostrom KJ, Huisman J, et al. Restrictions in daily life after retinoblastoma from the perspective of the survivors. Pediatr Blood Cancer. 2010;54:110–115.
   Google Scholar
• Künkele A, Jurklies C, Wieland R, et al. Chemoreduction improves eye retention in patients with retinoblastoma: a report from the German Retinoblastoma Reference Centre. Br J Ophthalmol. 2013;97:1277–1283.
   PubMed Web of Science ®Google Scholar
• Chan HS, Gallie BL, Munier FL, Beck Popovic M. Chemotherapy for retinoblastoma. Ophthalmol Clin North Am. 2005;18:55–63.
   PubMedGoogle Scholar
• Chantada GL, Dunkel IJ, de Dávila MTG, Abramson DH. Retinoblastoma patients with high risk ocular pathological features: who needs adjuvant therapy? Br J Ophthalmol. 2004;88:1069–1073.
   PubMed Web of Science ®Google Scholar
• Sirin S, Schlamann M, Metz KA, et al. Diagnostic image quality of gadolinium-enhanced T1-weighted MRI with and without fat saturation in children with retinoblastoma. Pediatr Radiol. 2013;43:716–724.
   PubMed Web of Science ®Google Scholar
• Messmer EP, Sauerwein W, Heinrich T, et al. New and recurrent tumor foci following local treatment as well as external beam radiation in eyes of patients with hereditary retinoblastoma. Graefes Arch Clin Exp Ophthalmol. 1990;228:426–431.
   PubMed Web of Science ®Google Scholar
• Adan L, Trivin C, Sainte-Rose C, Zucker JM, Hartmann O, Brauner R. GH deficiency caused by cranial irradiation during childhood: factors and markers in young adults. J Clin Endocrinol Metab. 2001;86:5245–5251.
   PubMed Web of Science ®Google Scholar
• Brualla L, Mayorga PA, Flühs A, Lallena AM, Sempau J, Sauerwein W. Retinoblastoma external beam photon irradiation with a special “D”-shaped collimator: a comparison between measurements, Monte Carlo simulation and a treatment planning system calculation. Phys Med Biol. 2012;57:7741–7751.
   PubMed Web of Science ®Google Scholar
• Bornfeld N, Schüler A, Bechrakis N, Henzt G, Havers W. Treatment protocols in pediatric oncology: preliminary results of primary chemotherapy in retinoblastoma. Klin Padiatr.1997;209: 216–221.
   Google Scholar
• Heiduk M, Päge I, Kliem C, Abicht K, Klein G. Pediatric reference intervals determined in ambulatory and hospitalized children and juveniles. Clin Chim Acta. 2009;406:156–161.
   PubMed Web of Science ®Google Scholar
• Matos V, Van Melle G, Boulat O, Markert M, Bachmann C, Guignard J. Urinary phosphate/creatinine, calcium/creatinine, and magnesium/creatinine ratios in a healthy pediatric population. J Pediatr. 1997;131:252–257.
   PubMed Web of Science ®Google Scholar
• Institute of Medicine. Dietary Reference Intakes for Calcium and Vitamin D. Washington, DC: The National Academies Press; 2011.
   Google Scholar
• Holick MF. High prevalence of Vitamin D inadequacy and implications for health. Mayo Clin Proc. 2006;8:297–299.
   Google Scholar
• Blum W, Breier B. Radioimmunoassays for IGFs and IGFBPs. Growth Regul. 1994;4(Suppl):11–19.
   Google Scholar
• Blum WF, Englaro P, Hanitsch S, et al. Plasma leptin levels in healthy children and adolescents: dependence on body mass index, body fat mass, gender, pubertal stage, and testosterone. J Clin Endocrinol Metab. 1997;82:2904–2910.
   PubMed Web of Science ®Google Scholar
• Grasemann C, Wessels HT, Knauer-Fischer S, Richter-Unruh A, Hauffa BP. Increase of serum leptin after short-term pulsatile GnRH administration in children with delayed puberty. Eur J Endocrinol. 2004;150:691–698.
   PubMed Web of Science ®Google Scholar
• Schündeln MM, Goretzki SC, Hauffa PK, et al. Impairment of bone health in pediatric patients with hemolytic anemia. PLoS One. 2014;9:e108400.
   PubMed Web of Science ®Google Scholar
• Kleinerman RA, Tucker MA, Abramson DH, Seddon JM, Tarone RE, Fraumeni JF. Risk of soft tissue sarcomas by individual subtype in survivors of hereditary retinoblastoma. J Natl Cancer Inst. 2007;99:24–31.
   PubMed Web of Science ®Google Scholar
• Arikoski P, Komulainen J. Alterations in bone turnover and impaired development of bone mineral density in newly diagnosed children with cancer: a 1-year prospective study. J Clin Endocrinol Metab. 1999;84:3174–3181.
   Google Scholar
• Rosen GP, Beebe KL. Vitamin D levels differ by cancer diagnosis and decline over time in survivors of childhood cancer characteristics of study subjects. Pediatr Blood Cancer. 2013; 60:949–952.
   Google Scholar
• Thierfelder W, Dortschy R, Hintzpeter B, Kahl H, Scheidt-Nave C. [Biochemical measures in the German Health Interview and Examination Survey for Children and Adolescents (KiGGS)]. Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz. 2007;50:757–770.
   PubMed Web of Science ®Google Scholar
• Holick MF. Vitamin D deficiency. N Engl J Med. 2007;357:266–281.
   PubMed Web of Science ®Google Scholar
• Sinha A, Avery P, Turner S, Bailey S, Cheetham T. Vitamin D status in paediatric patients with cancer. xxx. 2011; xx(August 2010):594–598.
   Google Scholar
• Modan-Moses D, Pinhas-Hamiel O, Munitz-Shenkar D, Temam V, Kanety H, Toren A. Vitamin D status in pediatric patients with a history of malignancy. Pediatr Res. 2012;72:620–624.
   PubMed Web of Science ®Google Scholar
• Winzenberg T, Powell S, Shaw KA, Jones G. Effects of vitamin D supplementation on bone density in healthy children: systematic review and meta-analysis. BMJ. 2011;342:1–9.
   Web of Science ®Google Scholar
• Gallo S, Comeau K, Sharma A, et al. Redefining normal bone and mineral clinical biochemistry reference intervals for healthy infants in Canada. Clin Biochem. 2014;47:27–32.
   PubMed Web of Science ®Google Scholar
• Holick MF, Binkley NC, Bischoff-Ferrari HA, et al. Evaluation, treatment, and prevention of vitamin D deficiency: an Endocrine Society clinical practice guideline. J Clin Endocrinol Metab. 2011;96:1911–1930.
   PubMed Web of Science ®Google Scholar
• Binkley T, Specker B, Wittig T. Centile curves for bone densiometry measurements in healthy males and females ages 5–22 yr. J Clin Densitom. 2003;5:343–353.
   Web of Science ®Google Scholar
• Schönau. Problems of bone analysis in childhood and adolescence. Pediatr Nephrol. 1998; 12:420–429.
   Google Scholar
• Wong FL, Boice JD Jr, Abramson DH, et al. Cancer incidence after retinoblastoma. Radiation dose and sarcoma risk. JAMA. 1997;278:1262–1267.
   PubMed Web of Science ®Google Scholar
• Nahum M, Gdal-On M, Kuten A, Herzl G, Horovitz Y, Weyl Ben Arush M. Long-term follow-up of children with retinoblastoma. Pediatr Hematol Oncol. 2001;18:173–179.
   PubMed Web of Science ®Google Scholar
• Rueegg C, Gianinazzi M. Do childhood cancer survivors with physical performance limitations reach healthy activity levels? Pediatr blood. Pediatr Blood Cancer. 2013; 60:1714–1720.
   Google Scholar
• Lampert T, Mensink GBM, Romahn N, Woll A. [Physical activity among children and adolescents in Germany. Results of the German Health Interview and Examination Survey for Children and Adolescents (KiGGS)]. Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz. 2007;50:634–642.
   PubMed Web of Science ®Google Scholar