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Pediatric Hematology and Oncology Volume 12, 1995 - Issue 4
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Original Article

Comparative Effect of 100 Versus 250 μ/m2/day of G-CSF in Pediatric Patients with Neutropenia Induced by Chemotherapy

Masaru Kubota Department of Pediatrics, Kyoto University, Kyoto, Japan
,
Yuichi Akiyama Department of Pediatrics, Kyoto University, Kyoto, Japan
,
Haruki Mikawa Department of Pediatrics, Kyoto University, Kyoto, Japan
&
Tsutomu Tsutsui Section of Pediatrics, Kobe City General Hospital, Kobe, Japan
Pages 393-397 | Received 19 Sep 1994, Accepted 28 Nov 1994, Published online: 09 Jul 2009

References

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  • Gabrilove J. The development of granulocyte colony-stimulating factor in its various clinical applications. Blood. 1992; 80: 1382–1385
  • Morstyn G, Campbell L, Souza L M. Effect of granulocyte colony stimulating factor on neutropenia induced by cytotoxic chemotherapy. Lancet 1988; i: 667–672
  • Lindemann A, Herrmann F, Oster W. Hematologic effects of recombinant human granulocyte colony-stimulating factor in patients with malignancy. Blood. 1989; 74: 2644–2651
  • Morstyn G, Campbell L, Lieschke G. Treatment of chemotherapy-induced neutropenia by subcutaneously administered granulocyte colony-stimulating factor with optimization of dose and duration of therapy. J Clin Oncol. 1989; 7: 1554–1562
  • Eguchi K, Sasaki S, Tamura T. Dose escalation study of recombinant human granulocyte-colony-stimulating factor (KRN 8601) in patients with advanced malignancy. Cancer Res. 1989; 49: 5221–5224
  • Ohno R, Tomonaga M, Ohshima T. A randomized controlled study of granulocyte colony stimulating factor after intensive induction and consolidation therapy in patients with acute lymphoblastic leukemia. Int J Hematol. 1993; 58: 73–81
  • Bokemeyer C, Schmoll H J, Metzner B. Comparison of 5 vs 10 μg/kg per day of GM-CSF following dose-intensified chemotherapy with cisplatin, etoposide, and ifosfamide in patients with advanced testicular cancer. Ann Hematol. 1993; 67: 75–79

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