Antibodies to SOX13 (ICA12) are Associated with Type 1 Diabetes

References

• Baekkeskov S, Neilsen J H, Marner B, Bilde T, Ludvigsson J, Lernmark A. Autoantibodies in newly diagnosed diabetic children immunoprecipitate human pancreatic islet cell proteins. Nature 1982; 298: 167–169
   PubMed Web of Science ®Google Scholar
• Atkinson M A, Maclaren N K, Scharp D W, Lacy P E, Riley W. J. 64000 Mr autoantibodies as predictors of insulin dependent diabetes. Lancet 1990; 335: 1357–1360
   PubMed Web of Science ®Google Scholar
• Thivolet C H, Tappaz M, Durand A, Petersen J, Steffanutti A, Chatelain P, Vialettes B. Glutamic acid decarboxylase (GAD) autoantibodies are additional predictive markers of Type I (insulin dependent) diabetes in high risk individual. Diabetologia 1992; 35: 570–576
   PubMedGoogle Scholar
• Hagopian W A, Michelsen B, Karlsen A E, Larsen F, Moody A, Grubin C E, Rowe R, Petersen J, McEvoy R, Lernmark A. Autoantibodies in IDDM primarily recognise the 65000-Mr rather than the 67000-Mr isoform of glutamic acid decarboxylase. Diabetes 1993; 42: 631–636
   PubMed Web of Science ®Google Scholar
• Myers M A, Mackay I R, Zimmet P Z, Rowley M. J. Autoantibodies to glutamate decarboxylase in insulin dependent diabetes mellitus. The Diabetes Annual 1996; 10: 15–31
   Google Scholar
• Rabin D U, Pleasic S M, Shapiro J A, Yoo-Warren H, Oles J., Hicks J M, Goldstein D E. Rae PMM Islet cell antigen 512 is a diabetes-specific autoantigen related to protein tyrosine phosphatases. J Immunol. 1994; 152: 3183–3138
   PubMed Web of Science ®Google Scholar
• Lan M S, Wasserfall N K, Maclaren N K, Notkins A. L. 1A-2, a transmembrane protein of the protein tyrosine phosphatase family, is a major autoantigen in insulin-dependent diabetes mellitus. Proc Natl Acad Sci USA 1996; 93: 63–67
   Google Scholar
• Xie H, Zhang B, Matsumoto Y, Li Q., Notkins A L, Lan M. S. Autoantibodies to 1A-2 and IA-2β in insulin dependent diabetes mellitus recognise conformational epitopes. J. Immunol. 1997; 159: 3662–3667
   PubMedGoogle Scholar
• Passini N, Larigan J D, Genovese S, Appella E, Sinigaglia F, Rogge L. The 37/40 kDa autoantigen in insulin-dependent diabetes mellitus is the putative tyrosine phosphatase. Proc Natl Acad Sci USA 1995; 92: 9412–9416
   PubMed Web of Science ®Google Scholar
• Kawasaki E, Yu J, Rewers M J, Hutton J C, Eisenbarth G. S. Definition of multiple lCA512/phogrin autoantibody epitopes and detection of intramolecular epitope spreading in relatives of patients with type I diabetes. Diabetes 1998; 47: 733–742
   PubMedGoogle Scholar
• Feeney S J, Myers M A, Mackay I R, Zimmet P Z, Howard N, Verge C F, Rowley M. J. Evaluation of 1CA512As in combination with other islet cell autoantibodies at the onset of IDDM. Diabetes Care 1997; 20: 1403–1407
   PubMedGoogle Scholar
• Notkins A L, Lu J, Li Q, Vander Vegt F P, Wasserfall C, Maclaren N K, Lan M S. 1A-2 and 1A-2β are major autoantigens in IDDM and the precursors of the 40 kDa and 37 kDa tryptic fragments. J Autoimmun. 1996; 9: 677–682
   PubMedGoogle Scholar
• Gorus F K, Goubert P, Semakula C., Vandewalle C L, De Schepper J, Scheen A, Christie M R, Pipeleers D. G. IA-2-autoantibodies complement GAD65-autoantibodies in new-onset IDDM patients and help predict impending diabetes in their siblings. The Belgian diabetes registry. Diabetolo-gia 1997; 40: 95–99
   PubMedGoogle Scholar
• Mayrhofer M, Rabin D U, Messenger L, Standi E, Ziegler A. G. Value of ICA512 antibodies for prediction and diagnosis of type 1 diabetes. Exp Clin Endocrinol Diabetes 1996; 104: 228–234
   PubMedGoogle Scholar
• Myers M A, Rabin D U, Rowley M. J. Pancreatic islet cell cytoplasmic antibody in diabetes is represented by antibodies to islet cell antigen 512 and glutamic acid decarboxylase. Diabetes 1995; 44: 1290–1295
   PubMed Web of Science ®Google Scholar
• Hawa M, Rowe R, Lan M S, Notkins A L, Pozzilli P, Christie M R, Leslie R. D. Value of antibodies to islet protein tyrosine phosphatase-1 ike molecule on predicting type 1 diabetes. Diabetes 1997; 46: 1270–1275
   PubMedGoogle Scholar
• Rowley M J, Mackay I R, Chen Q Y, Knowles W J, Zimmet P. Z. Antibodies to glutamic acid decarboxylase discriminate major types of diabetes mellitus. Diabetes 1992; 41: 548–551
   PubMed Web of Science ®Google Scholar
• Rabin D U, Pleasic S M, Palmer-Crocker R, Shapiro J. A. Cloning and expression of IDDM-specific human autoantigens. Diabetes 1992; 41: 183–186
   PubMed Web of Science ®Google Scholar
• Kasimiotis H, Myers M, Argentaro A., Mertin S, Fida S, Ols-Son J, Ferrarro T, Rowley M., Harley V. The SRY-related protein. SOX 13, is a diabetes autoantigen expressed in pancreatic islets. Diabetes 2000; 49: 555–561
   PubMed Web of Science ®Google Scholar
• Grosschedl R, Giese K, Pagel J. HMG domain proteins: architectural elements in the assembly of nucleoprotein structures. TIG 1994; 10: 94–100
   PubMed Web of Science ®Google Scholar
• World Health Organisation. Diabetes mellitus report of a WHO study group. Technical report series 727. WHO, Geneva 1985
   Google Scholar
• Chen Q Y, Rowley M J, Byrne G C, Jones T W, Tuomi T, Knowles W J, Zimmet P Z, Mackay I. R. Antibodies to glutamic acid decarboxylase in Australian children with insulin dependent diabetes mellitus and their first-degree relatives. Pediatr Res. 1993; 34: 785–790
   PubMed Web of Science ®Google Scholar
• Tuomi T, Zimmet P, Rowley M J, Min H K, Vichayanrat A, Lee H K, Rhee B D, Vannasaeng S, Humphrey A R, Mackay I R. Differing frequency of autoantibodies to glutamic acid decarboxylase among Koreans. Thais, and Australians with diabetes mellitus. Clin Immunol Immunopathol. 1995; 74: 202–206
   PubMedGoogle Scholar
• Whittingham S, Byron S L, Tuomilehto J, Zimmet P Z, Myers M A, Vidgren G, Rowley M. J., Feeney S J, Koskela P, Tuomilehto-Wolf E, Mackay I. R. Autoantibodies associated with pre-symptotic insulin dependent diabetes mellitus in women. Diabetic Medicine 1997; 14: 678–685
   PubMedGoogle Scholar
• Bakos S, Mackay I R, Rowley M J, Knowles W, Zimmet P. Islet cell antibodies and other markers of autoimmunity and diabetes in Nauruans. Diabetologia 1991; 34: 796–800
   PubMedGoogle Scholar
• Morgenthaler N G, Seissler J, Achenbach P, Glawe D, Payton M, Meinck H M, Christie M R, Scherbaum W. A. Antibodies to the tyrosine phospatase-like protein IA-2 are highly associated with IDDM, but not with autoimmune endocrine diseases of stiff man syndrome. Autoimmunity 1997; 25: 203–211
   PubMed Web of Science ®Google Scholar
• Braining G J, Molenaar J L, Grobbee D E, Hofman A, Scheffer G J, Bruining H A, de Bruyn A M, Valkenburg H. A. Ten year follow up of study of islet cell antibodies and childhood diabetes mellitus. Lancet 1989; I: 1100–1103
   Google Scholar