References
- Kaplan M M. Primary biliary cirrhosis. N Engl J Med 1987; 316: 521–8
- Munoz L E, Thomas H C, Scheuer P J, Doniach D, Sherlock S. Is mitochondrial antibody diagnostic of primary biliary cirrhosis. Gut 1981; 22: 136–40
- Doniach D, Roitt I M, Walker J G, Sherlock S. Tissue antibodies in primary biliary cirrhosis, active chronic (lupoid) hepatitis, cryptogenic cirrhosis and other liver diseases and their clinical implications. Clin Exp Immunol 1966; 1: 237–62
- Sayers T J, Binder T, Berg P A. Heterogeneity of antimitochondrial antibodies: characterization and separation of the antigen associated with the pseudolupus erythematosus syndrome. Clin Exp Immuno 1979; 37: 68–75
- Labro M T, Andrieu M C, Weber M, Homberg J C. A new pattern of non-organ and non-species specific antiorganelle antibody detected by immunofluoresence: the mitochondrial antibody number 5. Clin Exp Immunol 1978; 31: 357–66
- Berg P A, Wiedmann K H, Sayers T, Kloppel G, Lindner H. Serolgoical classification of chronic cholestatic liver disease by the use of two different types of antimitochondrial antibodies. Lancet 1980; II: 1329–32
- Meek F, Khoury E L, Doniach D, Baum H. Mitochondrial antibodies in chronic liver diseases and connective tissue disorders: further characterization of autoantigens. Clin Exp Immunol 1980; 41: 43–54
- Lindenborn-Fotinos J, Sayers T J, Berg P A. Mitochondrial antibodes in primary biliary cirrhosis in association of the complement fixing antigen with a component of the mitochondrial FI-ATPase complex. Clin Exp Immunol 1982; 50: 267–74
- Schultheiss H-P, Berg P, Klingenberg M. The mitochondrial adenine nucleotide translocator is an antigen in primary biliary cirrhosis. Clin Exp Immunol 1984; 54: 648–54
- Mendel-Hartrig I, Frosteil A, Nelson B D. Primary biliary cirrhosis: assessment of the quantitative importance of the adenine nucleotide translocator protein as a major mitochondrial antigen. Clin Exp Immunol 1986; 66: 399–403
- Frazer I H, Mackay I R, Jordan T W, Whittingham S, Marzuki S. Reactivity of anti-mitochondrial autoantibodies in primary biliary corrhosis: definition of two novel mitochondrial polypeptide autoantigens. J. Immunol 1985; 135: 1739–45
- Fusconi M, Ghadiminejad I, Bianchi F B, Baum H, Bottazzo G F, Pisi E. Heterogeneity of antimitochondrial antibodies with the M2-M4 pattern by immunofluorescence as assessed by Western immunoblotting and enzyme linked immunosorbent assay. Gut 1988; 29: 440–7
- Manns M, Gerken G, Kyriatsoulis A, Trautwein C, Reske K, Meyer zum Buschenfelde K-H. Two different subtypes of antimitochondrial antibodies are associated with primary biliary cirrhosis: Identification and characterization by radioimmunoassay and immunoblotting. Hepatology 1987; 7: 893–9
- Ishii H, Saifuku K, Namihisa T. Reactivities and clinical relevance of antimitochondrial antibodies to four mitochondrial inner membrane proteins in sera of patients with primary biliary cirrhosis. Hepatology 1987; 7: 134–6
- Berg P A, Klein R. Molecular determination of the primary biliary cirrhosis specific M2 antigen. Hepatology 1988; 8: 200–1
- Gershwin M E, Mackay I R, Sturgess A, et al. Identification of a cDNA encoding the 70 Kd mitochondrial antigen recognized in the human autoimmune disease primary biliary cirrhosis. J Immunol 1987; 138: 3525–36
- Yeaman S J, Fussey S PM, Danner D J, James O FW, Mutimer D J, Bassendine M F. Primary biliary cirrhosis: Identification of two major M2 mitochondrial autoantigens. Lancet 1988; 1: 1067–9
- Gershwin M E, Coppel R L, Mackay I R. Primary biliary cirrhosis and mitochondrial autoantigens—insight from molecular biology. Hepatology 1988; 8: 147–51
- Gupta R C. Specificities and characteristics of mitochondrial protein antigen assessed by enzyme linked immunosorbent assay for anti-mitochondrial antibodies. Relationship to immunofluorescent and precipitating antibodies. Clin Exp Immunol 1985; 59: 604–12
- Kaplan M M, Gandolfo J V, Quaroni E G. An enzyme-linked immunosorbent assay (ELISA) for detecting anti-mitochondrial antibody. Hepatology 1984; 4: 727–30
- Leevy C M, Popper H, Sherlock S. Disease of the liver and biliary tract. Standardization of nomenclature, diagnostic criteria and diagnostic methodology. Year book Medical Publishers, Inc., Chicago 1976
- Miyachi K, Gupta R C, Dickson E R, Tan E M. Precipitating antibodies to mitochondrial antigens in patients with primary biliary cirrhosis. Clin Exp Immunol 1980; 39: 599–606
- Betterle C, Caretto A, Zeviani M, Fedini B, Salviati C. Demonstration and characterization of anti-human mitochondrial autonatibodies in idiopathic hypoparathyroidism and other conditions. Clin Exp Immuno 1985; 62: 353–60
- Laemmli U K. Cleavage of structural proteins during assembly of the head of bacteriophage T4. Nature 1970; 227: 680–5
- Towbin H, Staehelin T, Gordon J. Electrophoretic transfer of protein from polyacrylamide gels to nitrocellulose sheets: procedure and some applications. Proc Natl Acad Sci USA 1979; 76: 4350–4
- Lindenborn-Fotinos J, Baum H, Berg P A. Mitochondrial antibodies in primary biliary cirrhosis: species and nonspecies specific determinants of m2 antigen. Hepatology 1985; 75: 763–9
- Surh C D, Cooper A E, Coppell L, Leung P, Ahmed A, Dickson R, Gershwin M E. The predominance of IgG3 and IgM isotype antimitochondrial autoantibodies against recombinant fused mitochondrial polypeptide in patients with primary biliary cirrhosis. Hepatology 1988; 8: 290–5
- Baum H, Berg P A. The complex nature of mitochondrial antibodies and their relation to primary biliary cirrhosis. Semin Liver Dis 1981; 1: 309–21
- Stemerowicz R, Hopf U, Moller B, Wittenbrink C, Rodloff A, Reinhardt R, Freudenberg M, Galanos C. Are antimitochondrial antibodies in primary biliary cirrhosis induced by R (rough)-mutants of enterobacteriaceae. Lancet 1988; 2: 1166–70