5
Views
3
CrossRef citations to date
0
Altmetric
Original Article

The Time Course of Insulin Autoantibodies (IAA) in the Diabetes Prone BB Rat

, , &
Pages 79-88 | Received 12 Oct 1988, Published online: 07 Jul 2009

References

  • Chappel C I, Chappel W R. The discovery and development of the BB rat colony: An animal model of spontaneous diabetes mellitus. Metabolism 1983; 32: 8–10, (Suppl. 1)
  • Nakhooda A F, Like A A, Chappel C I, Wei C-N, Marliss E B. The spontaneously diabetic Wistar rat (the “BB” rat). Studies prior to and during development of the overt syndrome. Diabetologia 1978; 14: 199–207
  • Butler L, Guberski D L, Like A A. Genetic analysis of the BB/W diabetic rat. Can J Genet Cytol 1983; 25: 7–15
  • Marliss E B, Nakhooda A F, Poussier P, Sima A AF. The diabetic syndrome of the BB/Wistar rat: possible relevence to type I (insulin-dependent) diabetes in man. Diabetologia 1982; 22: 225–232
  • Rossini A A, Marks J P, Like A A. Immunology of insulin-dependent diabetes mellitus. Ann Rev Immunol 1985; 3: 289–320
  • Logothetopoulos J, Valiquette N, Madura E, Cvet D. The onset and progression of pancreatic insulitis in the overt, spontaneously diabetic, young adult BB rat studied by pancreatic biopsy. Diabetes 1984; 33: 33–36
  • Koevary S B, Williams D E, Williams R M, Chick W L. Passive transfer of diabetes in the BB/W rat. Science 1983; 220: 727–728
  • Like A A, Kislauskis E, Williams R M, Rossini A A. Neonatal thymectomy prevents spontaneous diabetes mellitus in the BB/W rat. Science 1982; 216: 644–646
  • Kurner T, Burkart V, Kolb H. Large increase of cytotoxic/suppressor T-lymphoblasts and eosinophils around manifestation of diabetes in the BB rats. Diabetes Res 1986; 3: 349–353
  • Dyrberg T, Poussier P, Nakhooda A F, Marliss E B, Lernmark A. Islet cell surface and lymphocyte antibodies often precede the spontaneous diabetes in the BB rat. Diabetologia 1984; 26: 159–165
  • Pollard D R, Gupta K, Mancino L, Hynie I. An immunofluorescence study of anti-pancreatic islet cell antibodies in the spontaneously diabetic BB rat. Diabetologia 1983; 25: 56–59
  • Like A A, Butler L, Williams R M, Appel M C, Weinger E J, Rossini A A. Spontaneous autoimmune diabetes mellitus in the BB rat. Diabetes 1982; 31: 7–13, (Suppl. 1)
  • Maclaren N K, Elder M E, Robbins V W, Riley W S. Autoimmune diathesis and T-lymphocyte immunoincompetences in BB rats. Metab Clin Exp 1983; 32: 92–96, (Suppl. 1)
  • Botazzo G F, Gorsuch A N, Dean B N, Cudworth A G, Doniach D. Completement-fixing islet cell antibodies in type I diabetes: possible monitors of active beta cell damage. Lancet 1980; i: 668–672
  • Lernmark A, Baekkeskov S. Islet cell antibodies - Theoretical and practical implications. Diabetologia 1981; 21: 431–435
  • Palmer J P, Asplin C M, Demons P, Lyen K, Tatpati O, Raghu P K, Pacquette T L. Insulin antibodies in insulin dependent diabetics before insulin treatment. Science 1983; 222: 1337–1339
  • Wilkin T J, Hoskins P J, Armitage M, Rodier M, Casey C, Diaz J-L, Pyke D A, Leslie R DG. Value of insulin autoantibodies as serum markers for insulin dependent diabetes mellitus. Lancet 1985; i: 480–481
  • McEvoy R C, Wilt M E, Ginsberg-Fellner F, Rubenstein P. Anti-insulin antibodies in children with type I diabetes. Genetic regulation of production and presence at diagnosis before insulin replacement. Diabetes 1986; 35: 634–651
  • Dean B M, Becker F, McNally J M, Tarn A C, Schwartz G, Gale E AM, Bottazzo G F. Insulin autoantibodies in the pre-diabetic period: Correlation with islet cell antibodies and the development of diabetes. Diabetologia 1986; 29: 339–342
  • Atkinson M A, Maclaren N K, Riley W J, Winter W E, Fisk D D, Spillar R P. Insulin autoantibodies as markers for insulin dependent diabetes mellitus. Diabetes 1987; 35: 894–898
  • Elder M, Maclaren N, Riley W, McConnell T. Gastric parietal cell and other autoantibodies in the BB rat. Diabetes 1982; 31: 313–318
  • Like A A, Appel M C, Rossini A A. Autoantibodies in the BB/W rat. Diabetes 1982; 31: 816–820
  • Bone A J, Walker R, Dean B M, Baird J D, Cooke A. Pre-diabetes in the spontaneously diabetic BB/E rat: pancreatic infiltration and islet cell proliferation. Acta Endocrinologica (Copenh) 1978; 15: 447–454
  • Pipeleers D, Vande de Winkel M, Dyrberg T, Lernmark A. Spontaneously diabetic BB rats have age-dependent islet β-cell-specific surface antibodies at clinical onset. Diabetes 1987; 36: 1111–1115
  • Wilkin T J, Kiesel U, Diaz J-L, Burkart V, Kolb H. Autoantibodies to insulin as serum markers for autoimmune insulitis. Diabetes Res 1986; 3: 173–174
  • Diaz J-L, Wilkin T. J. Differences in epitope restriction of autoantibodies to native human insulin (IAA) and antibodies to heterologous insulin (IA). Diabetes 1987; 36: 66–72
  • Wilkin T J, Armitage M. Markers for insulin dependent diabetes: towards early detection. Brit Med J 1986; 29: 1323–1326
  • Srikanta S, Ricker A T, McCullock D K, Soeldner J S, Eisenbarth G S, Palmer J P. Autoimmunity to insulin, beta cell dysfunction and development of insulin dependent diabetes. Diabetes 1986; 35: 139–42
  • McEvoy R C, Wilt M E, Ginsberg-Fellner F, Rubenstein P. Anti-insulin antibodies in children with type I diabetes. Genetic regulation of production and presence at diagnosis before insulin replacement. Diabetes 1986; 35: 634–651
  • Dyrberg T, Poussier P, Nakhooda A F, Marliss E B, Lernmark A. Humoral immunity in the spontaneously diabetic BB rat. Metabolism 1983; 32: 87–91, (Suppl. 1)
  • Baekkeskov S, Dyrberg T, Lernmark A. Autoantibodies to a 64-kilodalton islet cell protein precede the onset of spontaneous diabetes in the BB rat. Science 1984; 224: 1348–1350
  • Baekkeskov S, Landin M, Kristensen J M, Srikanta S, Braining G J, Mandrup-Poulsen T, et al. Antibodies to a 64,000 Mr human islet cell antigen precede the clinical onset of insulin-dependent diabetes. J Clin Invest 1987; 79: 926–934
  • Wilkin T J, Palmer J, Bonifacio E, Diaz J-L, Kruse V. First international workshop on the standardisation of insulin autoantibodies. Diabetologia 1987; 30: 676–677
  • Wilkin T J, Palmer J, Kurtz A, Bonifacio E, Diaz J-L. The second international workshop on the standardisation of insulin autoantibody (IAA) measurement. Diabetologia 1988; 31: 449–450
  • Wilkin T J. Autoimmunity and autoantibodies in type I diabetes. Immunogenetics of insulin dependent diabetes, A. H. Barnett. MTP Press Ltd., LancasterUK 1987; 54–79
  • Schernthaner G. Genetics of type 1 diabetes. Diabetes and Immunology: pathogenesis and immunotherapy, H. Kolb, G Schernthaner, F A Gries. Hans Huber, Bern 1983; 56: 64
  • Clarson C, Daneman D, Martin J. Subclinical diabetes mellitus in the BB rat. Diabetes Res 1986; 3: 237–240
  • Like A A, Weringer E J, Holdash A, McGill P, Atkinson D, Rossini A A. Adoptive transfer of autoimmune diabetes mellitus in Bio-Breeding/Worcester (BB/W) inbred and hybrid rats. J Immunol 1985; 134: 1583–1587
  • Mordes J P, Desemone J, Rossini A A. The BB rat. Diabetes/Metabolism Rev 1987; 3: 725–750
  • Kryspin-Sorensen I, Dyrberg T, Kastern W. Genetic heterogeneity in the major histocompatibility complex of various BB rat sublines. Diabetologia 1986; 29: 307–312
  • Kastern W, Dyrberg T, Scholler J, Kryspin-Sorensen I. Restriction fragment polymorphisms in the major histocompatibility complex of diabetic BB rats. Diabetes 1982; 13: 807–809

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.