Autoimmune Syndrome After Neonatal Induction of Tolerance to Alloantigens: Analysis of the Specificity and of the Cellular and Genetic Origin of Autoantibodies

References

• Goldman M, Feng H M, Engers H D, Hochman A, Louis J A, Lambert P H. Autoimmunity and immune complex disease after neonatal induction of transplantation tolerance in mice. J Imniunol. 1983; 131: 251–258
   PubMedGoogle Scholar
• Merino J, Qin H ‐Y, Schurmans S, Gretener D, Grau G E, Lambert P H. Thrombocytopenia associated with the induction of neonatal tolerance to alloantigens: immunopathogenic mechanisms. Eur J Immunol. 1989; 19: 1693–1699
   PubMedGoogle Scholar
• Schurmans S, Heusser C H, Qin H ‐Y, Merino J, Brighouse G, Lambert P H. In vivo effects of anti‐IL‐4 monoclonal antibody on neonatal induction of tolerance and on an associated autoimmune syndrome. J Immunol. 1990; 145: 2465–2474
   PubMedGoogle Scholar
• Simpson E, O'Hopp S, Harrison M, Mosier D, Melief K, Cantor H. Immunological disease induced by injecting FI lymphoid cells into certain parental strains. Immunology. 1974; 27: 989–1007
   PubMedGoogle Scholar
• Tateno M, Kondo N, Itoh T, Yoshiki T. Autoimmune disease and malignant lymphoma associated with host‐versus‐graft disease in mice. Clin Exp Immunol. 1985; 62: 535–544
   PubMedGoogle Scholar
• Hard R C, Moncure C W, Still W J S. Renal lesions with organized deposits and lipid as part of the host‐versus‐graft syndrome in parent/FI mouse chimeras. Lab Invest. 1973; 28: 468–476
   PubMedGoogle Scholar
• Goldman M, Abramowicz D, Lambert P, Van der Vorst P, Bruyns C, Toussaint C. Hyperactivity of donor B cells after neonatal induction of lymphoid chimerism in mice. Clin Exp Immunol. 1988; 72: 79–83
   PubMedGoogle Scholar
• Luzuy S, Merino J, Engers H D, Izui S, Lambert P H. Autoimmunity after induction of neonatal tolerance to alloantigens: role of B cell chimerism and FI donor B cell activation. J Immunol. 1986; 136: 4420–4426
   PubMedGoogle Scholar
• Merino J, Schurmans S, Luzuy S, Izui S, Vassalli P, Lambert P H. Autoimmune syndrome after induction of neonatal tolerance to alloantigens: effects of in vivo treatment with anti‐T cell subset monoclonal antibodies. J Immunol. 1987; 139: 1426–1431
   PubMedGoogle Scholar
• Merino J, Schurmans S, Duchosal M, Izui I, Lambert P H. Autoimmune syndrome after induction of neonatal tolerance to alloantigens: CD4+ T cells from the tolerant host activate auto‐reactive F1 B cells. J Immunol. 1989; 143: 2202–2208
   PubMed Web of Science ®Google Scholar
• Merino J, Schurmans S, Wen L, Brighouse G, Luzuy S, Lambert P H. Autoimmune syndrome after induction of neonatal tolerance to alloantigens: analysis of the role of donor T cells in the induction of autoimmunity. Clin Exp Immunol. 1990; 79: 273–278
   PubMedGoogle Scholar
• Datta S K, Patel H, Berry D. Induction of a cationic shift in IgG anti‐DNA autoantibodies: role of T helper cells with classical and novel phenotypes in murine models of lupus nephritis. J Exp Med. 1987; 165: 1252–1268
   PubMed Web of Science ®Google Scholar
• Madaio M P, Carlson J, Cataldo J, Ucci A, Migliorini P, Pankewycz. Murine monoclonal anti‐DNA antibodies bind directly to glomerular antigens and form immune deposits. J Immunol. 1987; 138: 2883–2889
   PubMed Web of Science ®Google Scholar
• Benzonana G, Skalli O, Gabbiani G. Correlation between the distribution of smooth muscle or non muscle myosins and alpha smooth muscle actin in normal and pathological soft tissues. Cell Motility and Cytoskeleton. 1988; 11: 260–274
   PubMed Web of Science ®Google Scholar
• Strzelecka‐Golaszewska H, Zmorzynski S, Mossakowsa M. Bovine aorta actin. Development of an improved purification procedure and comparison of polymerization properties with actins from other types of muscle. Biochim Biophys Acta. 1985; 828: 13–21
   PubMedGoogle Scholar
• Pardee J D, Spudich J A. Purification of muscle actin. Methods in Cell Biology: The Cytoskeleton, L Wilson. Academic Press. 1982; Vol 24: 271–288
   Google Scholar
• Strzelecka‐Golaszewska H, Prochniewicz E, Nowk E, Zmorzynski S, Drabikowski W. Chicken‐gizzard actin: polymerization and stability. Eur J Biochem. 1980; 104: 41–52
   PubMedGoogle Scholar
• Rosenberg S, Stracher A, Lucas R C. Isolation and characterization of actin and actin binding protein from human platelets. J Cell Biol. 1981; 91: 201–211
   PubMed Web of Science ®Google Scholar
• Geisler N, Weber K. Purification of smooth‐muscle desmin and a protein‐chemical comparison of desmins from chicken gizzard and hog stomach. Eur J Biochem. 1980; 111: 425–433
   PubMedGoogle Scholar
• Franke W W, Weber K, Osborn M, Schmid E, Freudenstein C. Antibody to prekeratin. Decoration of tonofilament‐like arrays in various cells of epithelial character. Exptl Cell Res. 1978; 116: 429–445
   PubMed Web of Science ®Google Scholar
• Reininger L, Shibata T, Schurmans S, Merino R, Fossati L, Lacour M, Izui S. Spontaneous production of anti‐mouse red blood cell autoantibodies is independent of the polyclonal activation in NZB mice. Eur J Immunol. 1990, in press
   Google Scholar
• Kohler G, Milstein C. Derivation of specific antibody‐producing tissue culture and tumor lines by cell fusion. Eur J Immunol. 1976; 6: 511–519
   PubMed Web of Science ®Google Scholar
• Maniatis T, Fritsch E, Sambrook J. Molecular Cloning. A Laboratory Manual. Cold Spring Harbor Laboratory, Cold Spring Harbor, New York 1982
   Google Scholar
• Auffray C, Rougeon F. Purification of mouse immunoglobulin heavy chain messenger RNAs from total myeloma tumor RNA. Eur J Biochem. 1980; 107: 303–314
   PubMedGoogle Scholar
• Kofler R, Duchosal M, Dixon F. Complexity, polymorphism and connectivity of murine Vk gene families. Immunogenetics. 1989; 29: 65–74
   PubMedGoogle Scholar
• Brodeur P H, Riblet R. The immunoglobulin heavy chain variable region (Igh‐V) locus in the mouse. I. One hundred Igh‐V genes comprise seven families of homologous genes. Eur J Immunol. 1984; 14: 922–930
   PubMed Web of Science ®Google Scholar
• Hayakawa K, Hardy R R, Honda M, Herzenberg L A, Steinberg A D, Herzenberg L A. Ly‐l B cells: Functionally distinct lymphocytes that secrete IgM autoantibodies. Proc Natl Acad Sci (USA). 1984; 81: 2494–2498
   PubMed Web of Science ®Google Scholar
• Izui S, Kabayakawa T, Zryd M J, Louis J, Lambert P H. Mechanism for induction of anti‐DNA antibodies by bacterial lipopolysccharides in mice. II.Correlation between anti‐DNA induction and polyclonal antibody formation by various polyclonal B lymphocyte activators. J Immunol. 1977; 119: 2157–2162
   PubMed Web of Science ®Google Scholar
• Izui S, MacConahey P J, Dixon F J. Increased spontaneous polyclonal activation of B lymphocytes in mice with spontaneous autoimmune disease. J Immunol. 1978; 121: 2213–2219
   PubMed Web of Science ®Google Scholar
• Ishigatsubo Y, Steinberg A D, Klinman D M. Autoantibody production is associated with polyclonal B cell activation in autoimmune mice which express the Ipr or gId genes. Eur J Immuno. 1988; 18: 1089–1094
   PubMedGoogle Scholar
• Shlomchick M J, Marshack‐Rothstein A, Wolfowicz C B, Rothstein T L, Weigert M G. The role of clonal selection and somatic mutation in autoimmunity. Nature 1987; 328: 805–809
   PubMedGoogle Scholar
• Schlomchick M J, Aucoin A H, Pisetsky D S, Weigert M G. Structure and function of anti‐DNA autoantibodies derived from a single autoimmune mouse. Proc Natl Acad Sci (USA). 1987; 84: 9150–9154
   PubMedGoogle Scholar
• Dziarski R. Autoimmunity: polyclonal activation or antigen activation. Immunol Today. 1988; 9: 340–342
   PubMedGoogle Scholar
• Stott D, Merino J, Schurmans S, Lambert P H. Expression of anti‐DNA clonotypes and the role of helper T‐lymphocytes during the autoimmune response in mice tolerant to alloantigens. Autoimmunity. 1988; 1: 253–266
   PubMedGoogle Scholar
• Seligmann M. The origin and nature of autoantibodies. Ann Inst Pasteur/immunol. 1986; 137: 149–182
   Google Scholar
• Gleichmann E, Pals S T, Rolink A G, Radaszkiewicz T, Gleichmann H. Graft‐versus‐host reactions: clues to the etiopathology of a spectrum of immunological diseases. Immunol Today. 1984; 5: 324–332
   PubMedGoogle Scholar
• Shlomchick M, Masulli M, Shan H, Radic M Z, Pizetsky D, Marshack‐Rothstein A, Weigert M. Anti‐DNA antibodies from autoimmune mice arise by clonal expansion and somatic mutation. J Exp Med. 1990; 171: 265–297
   PubMedGoogle Scholar
• Moller G. B cell lineages. Immunol Rev. 1986; 93: 5–169
   PubMedGoogle Scholar
• Defrance T, Vandervliet B, Durand I, Banchereau J. Human interleukin 4 down‐regulates the surface expression of CD5 on normal and leukemic B cells. Eur J Immunol. 1989; 19: 293–299
   PubMedGoogle Scholar
• Miller R A, Gralow J. The induction of LEU‐I antigen expression in human malignant and normal B cells by phorbol myristic acetate (PMA). J Immunol. 1984; 133: 3408–3414
   PubMed Web of Science ®Google Scholar
• Freedman A S, Boyd A, Bieber F R, Daley J, Rosen K, Horowitz J C, et al. Normal cellular counterparts of B cell chronic lymphocytic leukemia. Blood. 1987; 70: 418–427
   PubMed Web of Science ®Google Scholar
• Kruger M G, Riley R L, Riley E A, Elia J M. Bone marrow stro‐ma1 cells modulate both k light chain and Ly‐l antigen expression on Ly‐l+pre‐B cell lines in vitro. Blood. 1990; 76: 383–392
   PubMedGoogle Scholar
• Werner‐Favre C, Vischer T L, Wohlwend D, Zubler R H. Cell surface antigen CD5 is a marker for activated human B cells. Eur J Immunol. 1989; 19: 1209–1213
   PubMed Web of Science ®Google Scholar
• Hayakawa K, Hardy R R, Parks D R, Herzenberg L A. The ‘Ly‐l B’ cell subpopulation in normal, immunodefective, and autoimmune mice. J Exp Med. 1983; 157: 202–218
   PubMed Web of Science ®Google Scholar
• Scher I. The CBA/N mouse strain: an experimental model illustrating the influence of the X‐chromosome on immunity. Adv Immunol. 1982; 33: 1–71
   PubMedGoogle Scholar
• de la Hera A, Marcos M, Toribio M, Marquez C, Gaspar M, Martinez C. Development of Ly‐I+B cells in immunodeficient CBA/n mice. J Exp Med. 1987; 166: 804–809
   PubMedGoogle Scholar
• Kofler R, Dixon F J, Theophilopoulos A N. The genetic origin of autoantibodies. Immunol Today. 1987; 12: 374–379
   Google Scholar