3
Views
6
CrossRef citations to date
0
Altmetric
Original Article

Different Nature of the Proliferation Defects of GLD, LPR and MEV C57BL/6 Mouse Lymphoid Cells

, , &
Pages 233-240 | Received 26 Nov 1990, Published online: 07 Jul 2009

References

  • Shultz L D. Pleiotropic effects of deleterious alleles at the “motheaten” locus. Curr Topics Microbiol Immunol 1988; 137: 216–222
  • Theofilopoulos A N, Dixon F J. Murine models of Systemic Lupus Erythematosus. Adv Immunol 1985; 37: 269–390
  • Murphy E D. Lymphoproliferation (Ipr) and other single-locus models for murine lupus. Immunologic defects in laboratory animals. Plenum Publishing Corp, New York 1981; 143–173
  • Dumont F, Habbersett R G. Unusual cell surface properties of the T lymphocyte population expanding in MRL/Mp-lpr/lpr mice. Immunology 1982; 47: 271–281
  • Davidson W F, Dumont F J, Bedigian H G, Fowlkes B J, Morse HC., III. Phenotypic, functional, and molecular genetic comparisons of the abnormal lymphoid cells of C3H-lpr/lpr and C3H-gld/gld mice. J Immunol 1986; 136: 4075–4084
  • Ishida Y, Ueda G, Noguchi K, Nagasawa R, Hirose S, Sato H, Shirai T. Unique cell surface phenotypes of proliferating lymphocytes in mice homozygous for Ipr and gld mutations, defined by monoclonal antibodies to MRL/Mp-lpr/lpr T cells. Cell Immunol 1987; 105: 136–146
  • Budd R C, Mac Donald H R, Lowenthal J W, Davignon J L, Isui S, Cerottini J C. Growth and differentiation in vitro of the accumulating Lyt-2-/L3T4-subset in Ipr mice. J Immunol 1985; 135: 3704–3711
  • Hefeneider S H, Conlon P J, Dower S K, Henney C S, Gillis S. Limiting dilution analysis of interleukin 2 and colony-stimulating factor producer cells in normal and autoimmune mice. J Immunol 1984; 132: 1863–1868
  • Simon M M, Prester M, Nerz G, Kuppers R C. Quantitative studies on T-cell functions in MRL/Mp-lpr/lpr mice. Clin Immunol Immunopathol 1984; 33: 39–53
  • Mosbach-Ozmen L, Gavériaux C, Montecino-Rodriguez E, Loor F. The C57BL/6 nu/nu, Ipr/lpr mouse. III. Autoimmunity status. Thymus 1986; 8: 59–75
  • Trembleau S, Pflumio F, Kuntz L, Jachez B, Loor F. Immuno-globulin isotypes of C57BL/6 nu/nu, Ipr/lpr mice. Evidence for a lack of direct intrinsic effect of the Ipr gene on B cell hyper-activity. Autoimmunity 1991, in press
  • Mosbach-Ozmen L, Loor F. Bone marrow transfers in X-irradiated mice congenic at the Ipr locus: some paradoxical effects. Thymus 1987; 9: 197–210
  • Montecino-Rodriguez E, Loor F. Reciprocal haematopoietic cell transfers between C57BL/6 mice differing at the Ipr locus. Immunology 1991; 74, 1990, in press
  • Montecino-Rodriguez E, Loor F. Haematopoietic cell transfers between C57BL/6 mice differing at the Ipr or gld locus. Immunology 1991; 74, in press
  • Montecino-Rodriguez E, Jachez B, Loor F. Lymphoid cell transfers between adult C57BL/6 mice differing at the Ipr locus. Lack of lymphadenopathy transfer and effects on host survival. Thymus 1988; 11: 89–111
  • Jachez B, Montecino-Rodriguez E, Pflumio F, Fonteneau P, Loor F. Lymphoid cell transfers between adult C57BL/6 mice differing at the Ipr (lymphoproliferation) and/or nu (nude) locus. Humoral immunity phenotype of the chimeras. Immunology 1989; 68: 169–174
  • Kuntz L, Velin D, Pflumio F, Loor F. 1990. Adoptive transfer of viable motheaten humoral autoimmunity in cyclophospha-mide-immunosuppressed beige recipient mice. Immunology 1990; 70: 520–526
  • Kuntz L, Pflumio F, Velin D, Loor F. Adoptive transfer of viable motheaten (mev) humoral autoimmunity: IgM to IgG switch of the hyperglobulinemia in nude, beige mouse recipients. Immunology 1990; 71: 341–346
  • Kuntz L, Montecino-Rodriguez E, Jachez B, Roman D, Loor F. Adoptive transfer of viable motheaten pathology in sublethally irradiated-beige recipient mice. Immunology 1991; 73, in press
  • Wofsy D, Murphy E D, Roths J B, Dauphinée M J, Kipper S B, Talal N. Deficient interleukin 2 activity in MRL/Mp and C57BL/6J mice bearing the Ipr gene. J Exp Med 1981; 154: 1671–1680
  • Katagiri T, Tomiyama H, Kyuwa S, Kano K. Interleukin-2 responses of MRL/lpr mouse splenocytes and lymph node cells induced by TPA and A23 187. Int Archs Allergy appl Immunol 1987; 83: 167–173
  • Koizumi T, Nakao Y, Matsui T, Katakami Y, Nakagawa T, Fugita T. Synergistic induction by calcium ionophore and phorbol ester of interleukin-2 (IL-2) receptor expression, IL-2 production and proliferation in autoimmune MRL/Mp-lpr mice. Immunology 1986; 59: 43–49
  • Davignon J L, Budd R C, Ceredig R, Piguet P F, Mac Donald H R, Cerottini J C, Vassalli P, Izui S. Functional analysis of T cell subsets from mice bearing the Ipr gene. J Immunol 1985; 135: 2423–2428
  • Santoro T J, Malek T R, Rosenberg Y J, Morse HC, III, Steinberg A D. Signals required for activation and growth of autoimmune T lymphocytes. Mol Cell Immunol 1984; 1: 347–356
  • Cantrell D A, Smith K A. The interleukin-2 T-cell system: A new cell growth model. Science 1984; 224: 1312–1316
  • Altman A, Theofilopoulos A N, Weiner R, Katz D H, Dixon F J. Analysis of T cell function in autoimmune murine strains: Defects in production of and responsiveness to interleukin 2. J Exp Med 1981; 154: 791–808
  • Klein-Schneegans A S, Kuntz L, Fonteneau P, Loor F. Serum concentration of IgM, IgGl, IgG2b, IgG3 and IgA in C57BL/6 mice and their congenics at the Ipr (lymphoproliferation) locus. J. Autoimmunity 1989; 2: 869–875
  • Kuntz L, Fonteneau P, Loor F. Partial expression of the viable motheaten (mev) mutation in the heterozygous state: abnormal levels of serum immunoglobulins and natural anti-ssDNA antibodies. J Autoimmunity 1990; 3: 329–335

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.