References
- Lernmark A. Molecular biology of type 1 (insulin dependent) diabetes mellitus. Diabetologia 1985; 28: 195–203
- Henson V, Maclaren N, Winter W, Riley W, Rotter J, Wake–land E K. Molecular genetics of insulin–dependent diabetes mellitis. Mol Biol Med 1986; 3: 129–136
- Nerup J, Mandrup-Poulson T, Molvig J, Helqvist S, Wigensen L, Egeberg J. Mechanisms of pancreatic b˜–cell destruction in type I diabetes. Diabetes Care 1989; 11: 16–23
- Unanue E R, Allen P M. The basis of the immunoregulatory role of macrophages and other antigen presenting cells. Science 1987; 236: 551–557
- von Boehmer H. The developmental biology of T lymphocytes. Ann Rev Immunol 1988; 6: 309–326
- Marrack P, Kappler J. T–cell receptor. Science 1987; 238: 1073–1079
- Davis M M, Bjorkman P J. T–cell antigen receptor genes and T–cell recognition. Nature 1988; 334: 395–402
- Leiter E H, Prochazka M, Coleman D L. The non–obese diabetic (NOD) mouse. Am J Pathol 1987; 128: 380–383
- Kotzin B L, Barr V L, Palmer E. A large deletion within T–cell receptor beta–chain gene complex in New Zealand white mice. Science 1985; 229: 167–171
- Maniatis T, Frutsch E F, Sambrook J. Molecular Cloning. Cold Spring Harbor Press, Cold Spring Harbor, NY 1982
- Winter W E, Beppu H, Maclaren N K, Cooper D L, Bell G I, Wakeland E K. Restriction fragment length polymorphisms in the 5′ flanking region of the insulin I gene in the BB rat and other rat strains and absence of association with insulin dependent diabetes mellitus. Diabetes 1987; 36: 193–198
- Wakeland E K, Price-LaFace M, Henson V, Peck A B. Production of 35 H–2 homozygous strains from wild mice. Immun–ogenetics 1987; 26: 115–119
- Snodgrass H R, Kisielow P, Kiefer M, Steinmetz M, von Boehmer H. Ontogeny of the T–cell antigen receptor within the thymus. Nature 1985; 313: 592–595
- Dembic Z, Bannwarth W, Taylor B A, Steinmetz M. The gene encoding the T–cell receptor a–chain maps close to the Np–2 locus on mouse chromosome 14. Nature 1985; 314: 271–273
- Theofilopoulos A N. Molecular genetics of antigen receptor genes in murine lupus. New Horizons in Animal Models for Autoimmune Disease, M Kyogodu, H Wigzell. Academic Press, Tokyo 1987; 193–210
- Cazenave P-A, Bonhomme F, Guenet J L, Kindt T J. Correlation of C–r/ß phenotype with origins of laboratory mouse strains. Current Topics in Microbiology and Immunology 1986; 127: 301–306
- Huppi K, D'Hoostelaere L A, Jouvin–Marche E. The context of T cell receptor b˜ chain genes among wild and inbred mouse species. Current Topics in Microbiology and Immunology 1986; 127: 291–299
- D'Hoostelaere L A, Jouvin-Marche E, Huppi K. Localization of CT8 and Ck on mouse chromosome 6. lmmunogenetics 1985; 22: 277–283
- Winoto A, Mjolsness S, Hood L. Genomic organization of the genes encoding mouse T–cell receptor a–chain. Nature 1985; 316: 832–836
- Winter W E, Shimpo K, Obata M, Yamada K, Luchetta R. Immunogenetic analysis of beta cell autoimmunity in the NOD mouse: the relationship of insulitis to the T cell receptor ßnod gene and the Aßnod gene. Diabetes, 39: 975–982
- Yanagi Y, Hirose S, Nagasawa R, Shirai T, Mak T W, Tada T. Does the deletion within T cell receptor b˜–chain gene of NZW mice contribute to autoimmunity in (NZBxNZW)Fl mice?. Eur J Immunol 1986; 16: 1179–1182
- Kotzin B L, Palmer E. The contribution of NZW genes to lupuslike disease in (NZBxNZW)Fl mice. J Exp Med 1987; 165: 1237–1251
- Kolb H, Freytag G, Kiesel U, Kolb–Bachofen V. Spontaneous autoimmune reactions against pancreatic islets in mouse strains with generalized autoimmune disease. Diabetologia 1980; 19: 216–221
- Singer P A, McEvilly R J, Balderas R S, Dixon F J, Theofilopoulos A N. T–cell receptor a–chain variable–region haplotypes of normal and autoimmune laboratory mouse strains. Proc Natl Acad Sci 1988; 85: 7729–7733, USA;
- Winter W E, Yamada K, Maclaren N K, Tarnuzzer R, Luchetta R, Tarquinio J, Peck A B, Wakeland E K. The genetic evolution of the / region in the NOD mouse: comparison to other strains of mice. Lessons from Animal Diabetes II., E Shafir, A Renold. John Libbey & Co, London and Paris 1988; 105–111
- Acha-Orbea H, McDevitt H O. The first external domain of the nonobese diabetic mouse class II I–A b˜ chain is unique. Proc Natl Acad Sci 1987; 84: 2435–2439, USA;
- Hattori M, Buse J B, Jackson R A, Glimcher L, Dorf M E, Minami M, Makino S, Moriwaki K, Kuzuya H, Imura H, Strauss W M, Seidman J G, Eisenbarth G S. The NOD mouse: recessive diabetogenic gene in the major histocompatibility complex. Science 1986; 231: 733–735
- Wicker L S, Miller B J, Coker L Z, McNally S E, Scott S, Mullen Y, Appel M. Genetic control of diabetes and insulitis in the nonobese diabetic (NOD) mouse. J Exp Med 1987; 165: 1639–1654
- Prochazka M, Leiter E H, Serreze D V, Coleman D L. Three recessive loci required for insulin–dependent diabetes in nonobese diabetic mice. Science 1987; 237: 286–289
- Behlke M A, Spinella D G, Chou H S, Sha W, Hartl D L, Loh D Y. T–cell receptor b˜–chain expression: dependence on relatively few variable region genes. Science 1985; 229: 566–570
- Barth R K, Kim B S, Lan N C, Hunkapillar T, Sobiek N, Winoto A, Gershenfeld H, Okada C, Hansburg D, Weissman I L, Hood L. The murine T–cell receptor uses a limited repertoire of expressing Vb˜ gene segments. Nature 1985; 316: 517–523
- Singer P A, McEvilly R J, Bobart M, McConahey P J, Dixon F J, Theofilopoulos A N. The role of T cell receptor (TCR) Vα and MHC gene loci in models of autoimmunity. FASEB J 1988; 2: A1670