References
- Rees A J, Peters D K, Compston D AS, Batchelor J R. Strong association between HLA DRw2 and antibody mediated Good-pasture's syndrome. Lancet 1978; i: 966–968
- Nepom G T, Hansen J, Nepom B. The molecular basis for HLA class II associations with rheumatoid arthritis. J Clin Immunol 1986; 7: 1–7
- Sollid L M, Markussen G, Ek J, Gjerde H, Vartdal F, Thorsby E. Evidence for a primary association of celiac disease to a particular HLA-DQ α/β heterodimer. J Exp Med 1989; 169: 345–350
- Todd J A. Genetic control of autoimmunity in type I diabetes. Immunol Today 1990; 11: 122–129
- Altmann D M, Sansom D, Marsh S GE. What is the basis for HLA-DQ associations with autoimmune disease?. Immunology Today 1991; 12: 267–270
- Robbins P A, Maino V C, Werner N L, Brodsky F M. Activated T cells and monocytes have characteristic patterns of class II antigen expression. J Immunol 1988; 141: 1281–1287
- Sakurai M, Strominger J L. B-cell specific enhancer activity of conserved upstream elements of the class II major histocompatibility complex DQB gene. Proc Nail Acad Sci USA 1988; 85: 6909–6913
- Kobr M, Reith W, Herrero-Sanchez C, Mach B. Two DNA-binding proteins discriminate between the promoters of different members of the major histocompatibility complex class II multigene family. Mol Cell Biol 1990; 10: 965–971
- Del Pozzo G, Perfetto C, Neve Ombra M, Ding G-Z, Guardiola J, Maffei A. DNA polymorphisms in the 5′ flanking region of the HLA-DQAI gene. Immunogenetics 1992; 35: 176–182
- Andersen L C, Beaty I S, Nettles I N, Scyfried C E, Nepom G T, Nepom B S. Allelic polymorphism in transcriptional regulatory regions of HLA-DQB genes. J Exp Med 1991; 173: 181–192
- Birnbaum G, Kotilinek L. Immunologic differences in murine glial cells and their association with susceptibility to experimental allergic encephalomyelitis. J Neuroimmunol 1990; 26: 119–129
- Male D, Price G. Induction of la molecules on brain endo-thelium is related to susceptibility to experimental allergic encephalomyelitis. J Neuroimmunol 1989; 21: 87–90
- Trowsdale J, Lee J, Carey J, Grosveld F, Bodmer W. Sequences related to HLA-DRα chain on human chromosome 6: Restriction enzyme polymorphism detected with DCα chain probes. Proc Natl Acad Sci USA 1983; 80: 1972–1976
- Thorsby E, Lundkin K EA, Ronningen K S, Sollid L M, Vandal F. Molecular basis and functional importance of some disease associated HLA polymorphisms. Tissue Antigens 1989; 34: 39–49
- Kwok W W, Mickelson E, Masewicz S, Milner E CB, Hansen J, Nepom G T. Polymorphic DQα and DQβ interactions dictate class II determinants of allo-recognition. J Exp Med 1990; 170: 85–95
- Nepom B S, Schwarz D, Palmer J P, Nepom G T. Transcomplementation of HLA genes in IDDM. HLA DQ alpha and beta chains produce hybrid molecules in DR3/4 heterozygotes. Diabetes 1986; 36: 114–117
- Kwok W W, Schwan D, Nepom B S, Thurtle P, Hock R, Nepom G T. HLA-DQ molecules form α-β heterodimers of mixed iso-type. J Immunol 1988; 141: 3123–3127
- Kimoto M, Fathman G C. Antigen reactive T cell clones. I. Transcomplementing hybrid I-A region gene products function effectively in antigen presentation. J Exp Med 1980; 152: 759–763
- Svejgaard A, Jackobsen B K, Platz P, Ryder L P, Nerup J, Christy M, et al. HLA associations in insulin-dependent diabetes: Search for heterogeneity in different groups of patients from a homogeneous population. Tissue Antigens 1986; 28: 237–245
- Nepom G T, Erlich H. MHC class II molecules and autoimmunity. Ann Rev Immunol 1991; 9: 493–525
- Brown J H, Jardetzky Y, Saper M, Samraoui B, Bjorkman P J, Wiley D C. A hypothetical model of the foreign antigen binding site of class II histocompatibility molecules. Nature 1988; 332: 845–850
- Lundin K E, Gaudernack G, Qvigstad E, Sollid L M, Throsby E. T lymphocyte clones recognizing an HLA-DQw3.2 associated epitope involving residue 57 on the DQβ chain. Human Immunol 1988; 22: 235–241
- Lund T, O'Reilley L, Hutchings P, Kanagawa O, Simpson E, Gravely R, et al. Prevention of insulin-dependent diabetes mellitus in non-obese diabetic mice by transgenes encoding modified I-Aβ or normal I-Eα chain. Nature 1990; 345: 727–729
- Colonna M, Bresnahan M, Bahram S, Strominger J L, Spies T. Allelic variants of the human putative peptide transporter involved in antigen processing. Proc Natl Acad Sci USA 1992; 89: 3932–3936
- Mellins E, Kempin S, Smith S, Monji T, Pious D. A gene required for class II-restricted antigen presentation maps to the major histocompatibility complex. J Exp Med 1991; 174: 1607–1615
- Bosnes V, Qvigstad E, Lundin E A, Thorsby E. Recognition of a particular HLA-DQ heterodimer by a human γδ cell clone. Europ J Immunol 1990; 20: 1429–1433
- Amagai M, Klaus-Kovtun V, Stanley J R. Autoantibodies against a novel epithelial cadherin in pemphigus vulgaris. a disease of cell adhesion. Cell 1991; 67: 869–877
- Scharf S J, Friedman A, Brautbar C, Szafer F, Steinman L, Horn G, et al. HLA class II allelic variation and susceptibility to pemphigus vulgaris. Proc Notl Acad Sci USA 1988; 85: 3504–3508
- Scharf S J, Friedman A, Steinman L, Brautbar C, Erlich H. Specific HLA-DQB and HLA-DRBI alleles confer susceptibility to pemphigus vulgaris. Proc Natl Acad Sci USA 1989; 86: 6215–6219
- Spurkland A, Ronningen K S, Vandvik B, Thorsby E, Vandal F. HLA-DQAI and HLA-DQBI genes may jointly determine susceptibility to develop multiple sclerosis. Human Immunology 1991; 30: 69–75
- Francis D A, Thompson A J, Brookes P, Davey N, Lechler R I, McDonald W I, et al. Multiple sclerosis and HLA: Is the susceptibility gene really HLA-DR or -DQ?. Human Immunology 1991; 32: 119–124
- Takacs K, Kalman B, Gyodi E, Tauszik T, Palffy G, Kuntar L, et al. Association between the lack of HLA-DQw6 and the low incidence of multiple sclerosis in Hungarian gypsies. Immunogenetics 1990; 31: 383–385
- Heard R NS, Cullen C, Middleton D, et al. An allelic cluster of DQ restriction fragments is associated with multiple sclerosis: Evidence that a second haplotype may influence disease susceptibility. Human Immunol 1989; 25: 111–123
- Haegert D G, Michaud M, Schwab C, Tausey C, Decary E, Francis G. HLA-DRβ, -DQα and DQβ restriction fragment length polymorphisms in multiple sclerosis. J Neurosci Res 1989; 23: 46–54
- Mitchison N A. Immunoinhibitory genes. Current Biology 1991; 1: 87–88