A constitutive 65 kda chondrocyte protein as a target antigen in adjuvant arthritis in Lewis Rats

References

• van Eden W, Thole JER, van der Zee R, Nordzij A, van Embden JDA, Hensen EJ, Cohen IR. Cloning of the mycobacterial epitope recognized by T lymphocytes in adjuvant arthritis. Nature 1988; 331: 171–3
   PubMed Web of Science ®Google Scholar
• Billingham MEJ, Carney S, Butler R, Colston MJ., Mycobacterial A. 65 kD heat-shock protein induces antigen-specific suppression of adjuvant arthritis, but is not itself arthritoge-nic. J Exp Med 1990; 171: 339–44
   PubMed Web of Science ®Google Scholar
• Yang XD, Gasser J, Riniker B, Feige U. Treatment of adjuvant arthritis in rats: vaccination potential of a synthetic nonapeptide from the 65 kDa heat shock protein of mycobacteria. J Autoimmun 1990; 3: 11–23
   PubMedGoogle Scholar
• Yang XD, Gasser J, Feige U. Prevention of adjuvant arthritis in rats by a nonapeptide from the 65 kDa mycobacterial heat-shock protein. Clin Exp Immunol 1990; 81: 189–94
   PubMedGoogle Scholar
• Yang XD, Gasser J, Feige U. Prevention of adjuvant arthritis in rats by a nonapeptide from the 65 kDa mycobacterial heat-shock protein: specificity and mechanism. Clin Exp Immunol 1992; 87: 99–104
   PubMedGoogle Scholar
• Venner TJ, Gupta RS. Nucleotide sequence of rat hsp60 (chaperonin, GroEL analog) cDNA. Nucleic Acids Res 1990; 18: 5309
   PubMedGoogle Scholar
• Thole JE, Keulen WJ, De-Bruyn J, Kolk AH, Groothuis DG, Berwald LG, Tiesjema RH, van Embden JD. Characterization, sequence determination and immunogenicity of a 65 kDa protein of Mycobacterium bovis BCG expressed in E. coli K12. Infeclmmun 1987; 55: 1466–75
   PubMedGoogle Scholar
• Feige U, Cohen IR. The 65-kDa heat-shock protein in the pathogenesis, prevention and therapy of autoimmune arthritis and diabetes mellitus in rats and mice. Springer Semin Immunopathol 1991; 13: 99–113
   PubMedGoogle Scholar
• Van Eden W. Heat-shock proteins in autoimmune arthritis: a critical contribution based on the adjuvant arthritis model. APMIS 1990; 98: 383–94
   PubMed Web of Science ®Google Scholar
• CoHen IR. Autoimmunity to the chaperonins in the pathogenesis of arthritis and diabetes. Annu Rev Immunol 1991; 9: 567–89
   PubMed Web of Science ®Google Scholar
• Mollenhauer J., von der Mark K, Burmester GR, Gluckert K, Lütjen-Drecoll E, Brune K. Serum antibodies against chondrocyte cell surface proteins in osteoarthritis and rheumatoid arthritis. J Rheumatol 1988; 15: 1811–7
   PubMedGoogle Scholar
• Bang H, Mollenhauer J, Schulmeister A, van Eden W, Kaufmann SHE, Wand-Württemberger Brune K. Isolation and characterization of a cartilage specific membrane antigen (CH65): comparison with cytokeratins and heat shock proteins. Immunol, in press
   Google Scholar
• Alsalameh S, Mollenhauer J, Hain N, Stock KP, Kalden JR, Burmester GR. Cellular immune response toward human articular chondrocytes. Arthrit Rheum 1990; 33: 1477–86
   PubMed Web of Science ®Google Scholar
• Jindal S, Dudani AK, Singh B, Harley CB, Gupta RS. Primary structure of a human mitochondrial protein homologous to the bacterial and plant chaperonins and to the 65-kilodalton mycobacterial antigen. Mol Cell Biol 1989; 9: 2279–83
   PubMed Web of Science ®Google Scholar
• Singh B, Gupta RS. Expression of human 60-kD heat shock protein (HSP60 or PI) in Escherichia coli and the development and characterization of corresponding monoclonal antibodies. DNA Cell Biol 1992; 11: 489–96
   PubMedGoogle Scholar
• Yang XD, Feige U. Heat shock proteins in autoimmune disease. From causative antigen to therapy?. Experientia 1992; 48: 650–5
   PubMedGoogle Scholar
• DeGraeff-Meeder ER, van der Zee R, Rijkers GT, Schuur-Man HJ, Kuis W, Bijlsma JWJ, Zegers BJM, van Eden W. Recognition of human 60 kD heat shock protein by mononuclear cells from patients with juvenile chronic arthritis. Lancet 1991; 337: 1368–72
   PubMedGoogle Scholar
• Gaston JSH, Life PF, Jenner PJ, Colston MJ, Bacon PA. Recognition of a mycobacteria-specific epitope in the 65 kD heat-shock protein by synovial fluid-derived T cell clones. J Exp Med 1990; 171: 831–41
   PubMed Web of Science ®Google Scholar
• Herrmann E, Lohse AW, van der Zee R, van Eden W, Mayet WJ, Probst P, Poralla T, Meyer zum Biischenfelde KH, Fleischer B. Synovial fluid-derived Yersinia-reactive T cells responding to human 65-kDa heat-shock protein and heat-stressed antigen-presenting cells. Eur J Immunol 1991; 21: 2139–43
   PubMedGoogle Scholar
• Res PCM, Orsini DLM, van Laar JM, Janson AAM, Abou-Zeid C, De Vries RRP. Diversity in antigen recognition by Mycobacterium tuberculosis-rcactic T cell clones from the synovial fluid of rheumatoid arthritis patients. Eur J Immunol 1991; 21: 1297–302
   PubMed Web of Science ®Google Scholar
• Tsuolfa G, Rook GAW, Bahr GM, Sattar MA, Behbehani K, Young DB, Mehlert A, Van-Embden JDA, Hay FC, Isenberg DA, Lydyard PM. Elevated IgG antibody levels to the mycobacterial 65-kDa heat shock protein are characteristic of patients with rheumatoid arthritis. Scand J Immunol 1989; 30: 519–27
   PubMedGoogle Scholar
• Mollenhauer J, Schulmeister A. The humoral immune response to heat shock proteins. Experientia 1992; 48: 644–9
   PubMedGoogle Scholar
• Burmester GR, Altstidl U, Kalden JR, Emmrich F. Stimulatory response towards the 65 kDa heat shock protein and other mycobacterial antigens in patients with rheumatoid arthritis. J Rheumatol 1991; 18: 171–6
   PubMedGoogle Scholar
• Karlsson-Parra A, Söderström K, Ferm M, Ivanyi J, Kiessling R, Klareskog L. Presence of human 65 kD heat shock protein (hsp) in inflamed joints and subcutaneous nodules of RA patients. Scand J Immunol 1990; 31: 283–8
   PubMedGoogle Scholar
• DeGraefF-Meeder ER, Voorhorst M, van Eden W, Schuur-Man HJ, Huber J, Barkley D, Maini RN, Kuis W, Rijkers GT, Zegers BJM. Antibodies to the mycobacterial 65 kD heat-shock protein are reactive with synovial tissue of adjuvant arthritic rats and patients with rheumatoid arthritis and osteoarthritis. Am J Pathol 1990; 137: 1013–17
   PubMedGoogle Scholar
• Young BJJ, Mallya RK, Leslie RDG, Clark CJM, Hamblin TJ. Antikeratin antibodies in rheumatoid arthritis. Brit Med 1979; 2: 97–27
   PubMed Web of Science ®Google Scholar
• Ordeig J, Guardia J. Diagnostic value of antikeratin antibodies in rheumatoid arthritis. J Rheumatol 1984; 11: 602
   PubMed Web of Science ®Google Scholar
• Borg AA, Dawes PT, Mattey DL. Increased levels of IgA antibodies to cytokeratin-18 and epidermal keratin in rheumatoid arthritis. Arthrit Rheum 1993; 36: 229–33
   PubMedGoogle Scholar
• Rambukkana A, Das PK, Krieg S, Yong S, Le Poole IC, Bos JD. Mycobacterial 65,000 MW heat-shock protein shares a carboxy-terminal epitope with human epidermal cytokera-tin 1/2. Immunol 1992; 77: 267–76
   PubMed Web of Science ®Google Scholar
• Hampel FA, Ronchetti EM, Rousseeuw PJ, Stahel WA. Robust statistics. The approach based on influence functions. John Wiley Sons, New York 1986
   Google Scholar