Advanced search
Publication Cover
Immunopharmacology and Immunotoxicology Volume 10, 1988 - Issue 2
Submit an article Journal homepage
21
Views
29
CrossRef citations to date
0
Altmetric
Research Article

Effects of Lentinan on Cytotoxic Functions of Human Lymphocytes

Gergely Péater Second Department of Medicine and First Department of Surgery, Semmelweis University, Budapest, Hungary, Pharmaceuticals and Development Department, Ajinomoto Co., Inc., Tokyo, Japan
,
Vallent Káaroly Second Department of Medicine and First Department of Surgery, Semmelweis University, Budapest, Hungary, Pharmaceuticals and Development Department, Ajinomoto Co., Inc., Tokyo, Japan
,
BodÓA Imre Second Department of Medicine and First Department of Surgery, Semmelweis University, Budapest, Hungary, Pharmaceuticals and Development Department, Ajinomoto Co., Inc., Tokyo, Japan
,
FehÉAr Jáanos Second Department of Medicine and First Department of Surgery, Semmelweis University, Budapest, Hungary, Pharmaceuticals and Development Department, Ajinomoto Co., Inc., Tokyo, Japan
&
Yutaro Kaneko Second Department of Medicine and First Department of Surgery, Semmelweis University, Budapest, Hungary, Pharmaceuticals and Development Department, Ajinomoto Co., Inc., Tokyo, Japan
Pages 157-163 | Published online: 28 Sep 2008

References

  • Akiyarna Y, Hamuro J. Effect of antitumor polysaccharides on specific and non-specific immune responses and their immunological characteristics. Protein, Nucleic Acid and Enzyme 1981; 26: 208
  • Böyum A. Separation of lymphocytes from blood and bone marrow. Scand. J. Clin. Lab. Invest. 1968; 21, (Suppl. 97)
  • Chihara G, Hamuro J, Maeda Y Y., Arai Y, Fukuoka F. Fractionation and purification of the polysaccharides with marked anti-tumor activity. especially lentinan from Lentinus edodes (Berk.) Sing. (an edible mushroom). Cancer Res. 1970; 30: 2776
  • Gergely P, Nékám K, Láng I, Kalmár L, González-Cabello R, Perl A. Ketoconazole in vitro inhibits mitogen-induced blastogenesis, antibody-dependent cellular cytotoxicity, natural killer activity and random migration of human leukocytes. Immuno-pharmacology 1984; 7: 167
  • Herlyn D, Kaneko Y, Rowe J, Aoki T, Koprowski H. Monoclonal antibody-dependent murine macrophage-mediated cytoxicity against human tumors is stimulated by lentinan. Gann 1985; 76: 37
  • Herberman R E., Nunn-Hargrove ME. Augmentation of natural killer (NK) activity by lentinan. Manipulation of Host Defence Mechanisms, T Aoki, I Urushizaki, E Tsubura. Excerpta Medica, Amsterdam 1981; 188
  • Jondal M, Pross H. Surface markers on human B and T lymphocytes VI. Cytotoxicity against cell lines as a functional marker for lymphocyte subpopulations. Int. J. Cancer 1975; 15: 596
  • Kosaka A, Imaizumi A, Hattori Y, Yamashita A. Nature of the antitumor action of lentinan-endocrine therapy on the mammary tumor. Host defense mechanisms against cancer, I Urushizaki, T Aoki, E Tsubura. Excerpta Medica, Amsterdam 1986; 208
  • Láng I, Török K, Gergely P, Nékám K, Petrányi Gy. Effect of histamin-receptor blocking on human antibody-dependent cell-mediated cytotoxicity. Scand. J. Immunol. 1981; 13: 361
  • Láng I, Nékám K, Gergely P, Petrányi Gy. Effect of in vivo and in vitro treatment with dialyzable leukocyte extracts on human natural killer cell activity. Clin. Immunol. Immunopathol. 1982; 25: 139
  • Perl A, González-Cabello R, Láng I, Somos P, Gergely P. Depressed lectin-dependent cell-mediated cytotoxicity against adherent HEp-2 cells in patients with carcinoma of the uterine cervix. Cancer Immunol. Immunother. 1983; 15: 155
  • Perlmann P, Perlmann H. Contactual lysis of antibody-coated chicken erythrocytes by purified lymphocytes. Cell. Immunol. 1970; 1: 117
  • Taguchi T, Furue H, Kimura T, Kondo T., Hattori T, Itoh T, Ogawa N. End-point results of phase III study of lentinan. Jpn. J. Cancer Chemother. 1985; 12: 366
  • Taguchi T, Kaneko Y. Lentinan: an overview of experimental studies of its action against cancer. Host defense mechanisms against cancer, I Urushizaki, T Aoki, E Tsubura. Excerpta Medica, Amsterdam 1986; 221

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.