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Immunopharmacology and Immunotoxicology Volume 10, 1988 - Issue 1
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Research Article

Synergistic Cytotoxicity of Recombinant Human TNF and Various Anti-Cancer Drugs

Naoki Watanabe Department of Internal Medicine, Section 4 Sapporo Medical College, South-1, West-16, Sapporo, 060, Japan
,
Yoshiro Niitsu Department of Internal Medicine, Section 4 Sapporo Medical College, South-1, West-16, Sapporo, 060, Japan
,
Naofumi Yamauchi Department of Internal Medicine, Section 4 Sapporo Medical College, South-1, West-16, Sapporo, 060, Japan
,
Yoshiki Ohtsuka Department of Internal Medicine, Section 4 Sapporo Medical College, South-1, West-16, Sapporo, 060, Japan
,
Hisao Sone Department of Internal Medicine, Section 4 Sapporo Medical College, South-1, West-16, Sapporo, 060, Japan
,
Hiroshi Neda Department of Internal Medicine, Section 4 Sapporo Medical College, South-1, West-16, Sapporo, 060, Japan
,
Masahiro Maeda Department of Internal Medicine, Section 4 Sapporo Medical College, South-1, West-16, Sapporo, 060, Japan
&
Ichiro Urushizaki Department of Internal Medicine, Section 4 Sapporo Medical College, South-1, West-16, Sapporo, 060, Japan
 show all
Pages 117-127 | Published online: 28 Sep 2008

References

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  • Watanabe N., Niitsu Y., Neda H., Sone H., Yamauchi N., Umetsu T., Urushizaki I. Antitumor effect of tumor necrosis factor against various primarily cultured human cancer cells. Jpn. J. Cancer Res. (Gann) 1985; 76: 1115–1119
  • Tsujimoto M., Vilcek J. Tumor necrosis factor receptors in HeLa cells and their regulation by interferon γ. J.B.C. 1986; 261: 5384–5388
  • Watanabe N., Niitsu Y., Yamauchi N., Umeno H., Sone H., Neda H., Urushizaki I. Antitumor Synergism between recombinant human tumor necrosis factor and recombinant interferon γ. J. Biol. Resp. Modif.
  • Umeno H., Watanabe N., Sone H., Neda H., Yamauchi N., Maeda M., Niitsu Y., Urushizaki I. Synergistic effects of human recombinant TNF and hyperthermia on in vitro cytotoxicity and artificial metastasis. Jpn. J. Cancer Chemother. 1987; 14: 1286–1291
  • Watanabe N., Umeno H., Sone H., Neda H., Yamauchi N., Umetsu T., Niitsu Y., Urushizaki I. The synergistic effect of human recombinant TNF in combination with hyperthermia. J. Jpn. Soc. Cancer Ther. 1987; 22: 632–637
  • Yamazaki S., Onishi E., Enami K., Natori K., Kohase M., Sakamoto H., Tanouchi M., Hayashi H. Proposal of standardized methods and reference for assaying recombinant human tumor necrosis factor. Japan J. Med. Sci. Biol. 1986; 39: 105–118
  • Steel G. G., Peckham M. J. Exploitable mechanisms in combined radiotherapy-chemotherapy : the concept of additivity. Int. J. Radiat. Oncol. Biol. Phys. 1979; 5: 85–91
  • Ostrove J. M., Gifford G. E. Stimulation of RNA synthesis in L-929 cells by rabbit tumor necrosis factor. Proc. Soc. Exp. Biol. Med. 1979; 160: 354–358
  • Ruff M. R., Gifford G. E. Rabbit tumor necrosis fractor: mechanism of action. Infect. Immun. 1981; 31: 380–385
  • Kull F. C., Cuatrecasas P. Possible requirement of internalization in the mechanism of in vitro cytotoxicity in tumor necrosis serum. Cancer Res. 1981; 41: 4885–4890
  • Watanabe N., Neda H., Ohtsuka Y., Sone H., Yamauchi N., Umetsu T., Niitsu Y., Urushizaki I. Analysis of the signalling pathway of TNF in normal cells and tumor cells. Jpn. J. Cancer Chemother. 1987; 14: 611–617

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