50
Views
60
CrossRef citations to date
0
Altmetric
Research Article

Immunotoxic Effects of Mercuric Compounds on Human Lymphocytes and Monocytes. I. Suppression of T-Cell Activation

, , &
Pages 539-553 | Published online: 28 Sep 2008

References

  • Shapiro I. M., Cornblath D. R., Sumner A. J., Uzzell B., Spitz L. K., Ship I. I., Bloch P. Neurophysiological and neuropsychological function in mercury-exposed dentists. Lancet 1982; 1: 1147
  • Nakatsuru S., Oohashi J., Nozaki H., Nakada S., Imura N. Effect of mercurials on lymphocyte functions. Toxicology 1985; 36: 297
  • Nordlind K. Inhibition of lymphoid cell DNA synthesis by metal allergens at various concentrations. Int. Archs Allergy Appl. Immun. 1983; 70: 191
  • Dieter M. P., Luster M. I., Boorman G. A., Jameson C. W., Dean J. H., Cox J. W. Immunological and biochemical responses in mice treated with mercuric chloride. Toxicol and Appl. Pharmacol. 1983; 68: 218
  • Pelletier L., Pasquier R., Rossert J., Druet P. HgClo induces nonspecific immunosuppression in Lewis rats. Eur. J. Immunol. 1987; 17: 49
  • Blakley B. R., Sisodia C. S., Mukkur T. K. The effect of meythylmercury, tetraethyl lead, and sodium arsenite on the humoral immune response in mice. Toxicol, and Appl. Pharmacol. 1980; 52: 245
  • Castranova V., Bowman L., Reasor M. J., Miles P. R. Effects of heavy metal ions on selected oxidative metabolic processes in rat alveolar macrophages. Toxicol, and Appl. Pharmacol. 1980; 53: 14
  • Malamud D., Dietrich S. A., Shapiro I. M. Low levels of mercury inhibit the respiratory burst in human polymorphonuclear leukocytes. Biochem. Biophys. Res. Comm. 1985; 128: 1145
  • Contrino J., Marucha P., Ribaudo R., Ference R., Bigazzi P. E., Kreutzer D. L. Effects of mercury on human polymorphonuclear leukocyte function in vitro. Am. J. Pathol. 1988; 132: 110
  • Nordlind K., Liden S. Mercuric chloride inhibition of leukocyte migration. Immunopharm. Immunotox. 1980; 12: 715
  • Ilback N. Effects of methyl mercury exposure on spleen and blood natural killer (NK) cell activity in the mouse. Toxicol. 1991; 67: 117
  • Nordlind K. Fractionation of human thymocytes and peripheral blood lymphocytes on Percoll density gradients and DNA synthesis stimulating effect of mercuric chloride. Int. Archs. Allergy Appl. Immun. 1984; 75: 16
  • Kamata H., Shinomiya K., Mikawa H. Selective enhancement of human IgE production in vitro by synergy of pokeweed mitogen and mercuric chloride. Clin. Exp. Immunol. 1983; 53: 183
  • Hirsch F., Couderc J., Sapin C., Fournie G., Druet P. Polyclonal effect of HgCl2 in the rat, its possible role in an experimental autoimmune disease. Eur. J. Immunol. 1982; 12: 620
  • Reardon C. L., Lucas D. O. Heavy metal mitogenesis: Zn++ and Hg+ induce cellular cytotoxicity and interferon production in murine T lymphocytes. Immunobio. 1987; 175: 455
  • Baran D., Vendeville B., Vial M. C., Cosson C., Bascou C., Teychenne P., Druet P. Effect of cyclosporine A on mercury-induced autoimmune glomerulonephritis in the Brown Norway rat. Clin. Nephrology 1986; 25(Suppl 1)S175
  • Pelletier L., Pasquier R., Hirsch F., Sapin C., Druet P. Autoreactive T cells in mercury induced autoimmune disease: in vitro demonstration. J. Immunol. 1986; 137: 2548
  • Feuerman E. J. Recurrent contact dermatitis caused by mercury in amalgam dental fillings. Int. J. Dermatol. 1975; 14: 657
  • Ochel M., Vohr H. W., Pfeiffer C., Gleichmann E. IL-4 is required for the IgE and IgGl increase and IgGl autoantibody formation in mice treated with mercuric chloride. J. Immunol. 1991; 146: 3006
  • Shenker B. J., McArthur W. P., Tsai C. C. Immune suppression induced by Actinobacillus actinomycetemcomitans. I. Effects on human peripheral blood lymphocyte responses to mitogens and antigens. J. Immunol. 1982; 128: 148
  • Boyum A. Separation of leukocytes form blood and bone marrow. Scan. J. Clin. Lab. Invest. 1968; 21(Suppl. 97)1
  • Shenker B. J., Vitale L. A., Welham D. A. Immune suppression induced by Actinobacillus actinomycetemcomitans: effects on immunoglobulin production by human B cells. Infect. Immun. 1990; 58: 3856

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.