65
Views
52
CrossRef citations to date
0
Altmetric
Research Article

Effects of the Angiotensin Converting Enzyme Inhibitor Captopril on Experimental Autoimmune Encephalomyelitis

, , &
Pages 471-491 | Published online: 27 Sep 2008

References

  • Ehlers M., Riordan J. F. Angiotensin-converting enzyme: new concepts regarding its biological role. Biochemistry 1989; 28: 5311–5317
  • Hooper N. Angiotensin converting enzyme: implications from molecular biology for its physiological functions. Int. J. Biochem. 1991; 23: 641–647
  • Brownlees J., Williams C. H. Peptidases, peptides and the mammalian blood-brain barrier. J. Neurochem. 1993; 60: 793–803
  • Lieberman J. Elevation of angiotensin-converting-enzyme (ACE) level in sarcoidosis. Am. J. Med. 1975; 59: 365–372
  • Goto M., Fujisawa M., Yamada A., Okabe T., Takaku F., Sasano M., Nishioka K. Spontaneous release of angiotensin converting enzyme and interleukin 1β from peripheral blood monocytes from patients with rheumatoid arthritis under a serum free condition. Ann. Rheum. Dis. 1989; 49: 172–176
  • Goto M., Sasano M., Fuzisawa M., Okabe T., Nishizawa K. Constitutive production of angiotensin converting enzyme from rheumatoid nodule cells under serum free conditions. Ann. Rheum. Dis. 1992; 51: 741–742
  • Veale D., Yanni G., Bresnihan B., Fitz Gerald. O. Production of angiotensin converting enzyme by rheumatoid synovial membrane. Ann. Rheum. Dis. 1992; 51: 476–480
  • Weinstock J. V., Blum A. M. Isolated liver granulomas of murine Schistosoma mansoni contain components of the angiotensin system. J. Immunol. 1983; 131: 2529–2532
  • Weinstock J. V., Blum A. M., Kassab J. T. Angiotensin II is chemotactic for a T-cell subset which can express migration inhibition factor activity in murine schistosomiasis mansoni. Cell. Immunol. 1987; 107: 180–187
  • Weinstock J. V., Ehrinpreis M. N., Boros D. L., Gee J. B. Effect of SQ 14225, an inhibitor of angiotensin-I converting enzyme, on the granulomatous response to Schistosoma mansoni eggs in mice. J. Clin. Invest. 1981; 67: 931–936
  • Lieberman J., Sastre A. Serum angiotensin-converting enzyme: elevations in diabetes mellitus. Ann. Int. Med. 1980; 93: 825–826
  • Lieberman J., Rea T. Serum angiotensin converting enzyme in leprosy and coccidioidomycosis. Ann. Int. Med. 1977; 87: 422–425
  • Schweisfurth H., Wernze H. Changes in angiotensin converting enzyme in patients with viral hepatitis and liver cirrhosis. Acta Hepato-Gastroenterol. 1979; 26: 207–210
  • Schweisfurth H., Schi S., öberg-Schiegnitz Kuhn W., Parusel B. Angiotensin I converting enzyme in the cerebrospinal fluid of patients with neurological diseases. Klin. Wochenschrift. 1987; 65: 955–958
  • Cohen J., Constantinescu C., Grossman R., Goodman D. Serum angiotensin-conevrting enzyme in multiple sclerosis. Neurology 1994; 44: A211
  • Foris G., Dezsö B., Medgyesi G. A., Füst G. Effect of angiotensin II on macrophage functions. Immunology 1983; 48: 529–535
  • Eisenlohr L. C., Bacik I., Bennink J. R., Bernstein K., Yewdell J. W. Expression of a membrane protease enhances presentation of endogenous antigens to MHC cals I-restricted T lymphocytes. Cell 1992; 71: 963–972
  • Kozlowski S., Corr M., Takeshita T., Boyd L. F., Pendleton C. D., Germain R. N., Berzofsky J. A., Margulies D. H. Serum angiotensin-1 converting enzyme activity processes a human immunodeficiency virus 1 gp160 peptide for presentation by major histocompatibilty complex class I molecules. J. Exp. Med. 1992; 175: 1417–1422
  • Kozlowski S., Corr M., Shirai M., Boyd L. F., Pendleton C. D., Berzofsky J. A., Margulies D. H. Multiple pathways are involved in the extracellular processing of MHC class I-restricted peptides. J. Immunol. 1993; 151: 4033–4044
  • Neefjes J. J., Momburg F. Cell biology of antigen presentation. Curr. Opin. Immunol. 1993; 5: 27–34
  • Johnsen S. A., Aurell M. Immunosuppressive action of captopril blocked by prostaglandin synthetase inhibitor. Lancet 1981; i: 1005
  • Delfraissy J.-F., Galanaud P., Balavoine J.-F., Wallon C., Dormont J. Captopril and immune regulation. Kidney Int. 1984; 25: 959–929
  • Deepe G. S., Taylor C. L., Srivastava L., Bullock W. E. Impairment of granulomatous inflammatory response to Histoplasma capsulatum by inhibitors of angiotensin-converting enzyme. Infect. Immun. 1985; 48: 395–401
  • Herlitz H., Tarkowski A., Svalander C., Volkmann R., Westberg G. Beneficial effect of Captopril on systemic lupus erythematosus-like disease in MRL Ipr/Ipr mice. Int. Arch. Allergy Appl. Immunol. 1988; 85: 272–277
  • Tarkowski A., Carlsten H., Herlitz H., Westberg G. Differential effects of captopril and enalapril, two angiotensin converting enzyme inhibitors, on immune reactivity in experimental lupus disease. Agents Actions 1990; 31: 96–101
  • Jaffe I. Angiotensin converting enzyme inhibitors in rheumatoid arthritis. Arthritis Rheum. 1984; 27: 840
  • Martin M. F. R., McKenna F., Bird H. A., Surrall K. E., Wright V. Captopril: a new treatment for rheumatoid arthritis?. Lancet 1984; ii: 1325–1327
  • Hafler D. A., Weiner H. L. MS: a CNS and systemic autoimmune disease. Immunol. Today 1989; 10: 104–107
  • Hallpike J. F., Adams C. W. M., Tourtellote W. W. “Multiple Sclerosis-Pathology, Diagnosis and Management.”. Chapman and Hall, London 1983
  • Zamvil S. S., Steinman L. The T lymphocyte in experimental allergic encephalomyelitis. Annu. Rev. Immunol. 1990; 8: 579–621
  • Matthews W. B., Compston A., Allen I. V., Martyn C. N. “McAlpine's Multiple Sclerosis.”. Churchill Livingstone, Edinburgh 1991
  • Traugot U., Raine C. S. Muliple sclerosis. Evidence for antigen presentation in situ by endothelial cells and astrocytes. J. Neurol. Sci. 1985; 69: 365–370
  • Deibler G. E., Martenson R. E., Kies M. W. Large scale preparation of myelin basic protein from central nervous tissue of several mammalian species. Prep. Biochem. 1972; 2: 139–165
  • Shasha S. M., Nusam D., Labin L., Kristal B., Steinberger O., Barzilai M., Makov E., Shkolnik T. Effect of converting enzyme inhibitor captopril on T cell function in essential hypertension. Nephron. 1991; 59: 586–590
  • Kunkel S., Chensue S., SH P. Prostaglandins as endogenous mediators of interleukin 1 production. Journal of Immunology 1986; 136: 186–192
  • Renz J.-H., Gong H., Schmidt A., Nain M., Gemsa D. Release of tumor necrosis factor-α from macrophages. J. Immunol. 1988; 141: 2388
  • Endres S., Fülle H.-J., Sinha B., Stall D., Dinarello C. A., Gerzer R., Weber P. C. Cyclic nucleotides differentailly regulate the synthesis of tumor necrosis factor-a and interleukin-1β by human mononuclear cells. Immunology 1991; 72: 56
  • Ruddle N. Tumor necrosis factor (TNFα) and lymphotoxin (TNFβ). Curr. Opin. Immunol. 1992; 4: 327–332
  • Sharief M., Thompson E. In vivo realtionship of tumor necrosis factor-alpha to blodd-brain barrier damage in patients with acute multiple sclerosis. J. Neuroimmunol. 1992; 38: 27–33
  • Selmaj J., Raine C., Cross A. Anti-tumor necrosis factor therapy abrogates autoimmune demyelination. Ann. Neurol. 1991; 30: 694–700
  • Nataf S., Louboutin J. P., Chabannes D., Feve J. R., Muller J. Y. Pentoxifylline inhibits experimental allergic encephalomyelitis. Acta Neurol. Scand. 1993; 88: 97–99
  • Rott O., Cash E., Fleischer B. Phosphodiesterase inhibitor pentoxifylline, a selective suppressor of T helper type 1-but not type 2-associated lymphokine production, prevents induction of experiemntal autoimmune encepahlomyelitis in Lewis rats. Eur. J. Immunol. 1993; 23: 1745–1751
  • Pi X., Chen X. Captopril and ramiprilat protect against free radical injury in isolated working rat hearts. J. Molec. Cell. Cardiol. 1989; 21: 1261–1271
  • Jay D., Cuéllar A., Zamorano R., Muñoz E., Gleason R. Captopril does not scavenge superoxide: captopril prevents O2− production by chelating copper. Arch. Biochem. Biophys. 1991; 290: 463–467
  • Gillis C. N., Chen X., Merker M. M. Lisinopril and ramiprilat protection of the vascular endothelium against free radical-induced functional injury. J. Pharmacol. Exp. Therap. 1992; 262: 212–216
  • Rabkin S. W. Cilazapril and captopril accelerate recovery from hypoxia in myocardial cell aggregates in culture. J. Cardiovasc. Pharmacol. 1992; 19: 394–401
  • Langemann H., Kabiersch A., Newcombe J. Measurement of low-molecular weight antioxidants, uric acid, tyrosine and tryptophan in plaques and white matter from patients with multiple sclerosis. Eur. Neurol. 1992; 32: 248–252
  • Powell T., Sussman J. G., Davies-Jones G. A. B. MR imaging in acute multiple sclerosis: ringlike appearance in plaques suggesting the presence of paramagnetic free radicals. AJNR 1992; 13: 1544–1546
  • Toshniwal P. K., Zarling E. J. Evidence for increased lipid peroxidation in multiple sclerosis. Neurochem. Res. 1992; 17: 205–207
  • Banks W. A, Kastin A. J. Interactions between the blood-brain barrier and endogenous peptides-emerging clinical implications. Am. J. Med. Sci. 1988; 295: 459–465
  • Segal M. B., Zlokovic B. V. “The Blood-Brain Barrier, Amino Acids and Peptides.”. Kluwer, Dordrecht 1990
  • Sorbi D., Fadly M., Hicks R., Alexander S., Arbeit L. Captopril inhibits the 72 kDa and 92 kDa matrix metalloproteinases. Kindey Int. 1993; 44: 1266–1272
  • Rosenberg G. A., Kornfeld M., Estrada E., Kelley R. O.L., Liotta A. W. G. Stetler-Stevenson. TIMP-2 reduces proteolytic opening of blood-brain barrier by type IV collagenase. Brain Res. 1992; 576: 203–207
  • Smith M. E. Proteolytic enzymes in demyelination. Neurochem. Clin. Neurol. 1980; 1: 1–10
  • Bird H. A., LeGallez P., Dixon J. S., Catalano M. A., Traficante A., Liauw L., Sussman H., Rotman H., Wright V. A clinical and bichemical assessment of a nonthiol ACE inhibitor (Pentopril; CGS-13945) in active rheumatoid arthritis. J. Rheumatol. 1990; 17: 603–608
  • Brosnan C., Goldmuntz E., Cammer W., Factor S., Bloom B., Norton W. Prazosin, an α1-adrenergic receptor antagonist, suppresses experimental autoimmune encephalomyelitis in the Lewis rat. Proc. Natl. Acad. Sci. USA 1985; 82: 5915–5919
  • Captopril Multicenter Research Group. A placebo-controlled trial of captopril in refractory chronic congestive heart failure. JACC 1983; 2: 755–763
  • Lewis E., Hunsicker L., Bain R., Rhode R. The effect of angiotensin-converting enzyme inhibition on diabetic nephropathy. New Engl. J. Med. 1993; 329: 1456–1462
  • Testa M., Anderson R., Nackley J., Hollenberg N. Quality of Life Hypertension Study Group. Quality of life and antihypertensive therapy in men-a comparison of captopril and enalapril. New Engl. J. Med. 1993; 328: 907–913
  • Hafler D., Fox D., Manning M., Schlossman S., Reinherz E., Weiner H. In vivo activated T lymphocytes in peripheral blood and cerebrospinal fluid of patients with multiple sclerosis. New Engl J. Med. 1985; 213: 1405–1411

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.