Variation in the Response of T Cells to Concanavalin a After In Vitro Exposure to Benzo[A]Pyrene and 2-Aminof'luorene

References

• Blanton R., Lyte M., Myers M., Bick P. Immunomodulation by polyaromatic hydrocarbons in mice and murine cells. Cancer Res. 1985; 46: 2735
   Web of Science ®Google Scholar
• Ginsberg G., Atherholt T., Butler G. Benzo[a]pyrene-induced immunotoxicity: Comparison to DNA adduct formation in vivo, in cultured splenocytes, and in microsomal systems. J. Tox. Envir. Health 1989; 28: 205
   PubMed Web of Science ®Google Scholar
• Hakim A. Peripheral blood lymphocytes from patients with cancer lack interleukin-2 receptor expression: Isolation of mRNA encoding IL-2R. Can. Det. Prev. 1988; 12: 59
   PubMedGoogle Scholar
• Kawabata T., White K. Suppression of the in vitro humoral immune response of mouse splenocytes by benzo(a)pyrene metabolites and inhibition of benzo(a)pyrene-induced immunosuppression by α-naphthoflavone. Cancer Res. 1987; 47: 2317
   PubMed Web of Science ®Google Scholar
• Lioy P. Human exposure to benzo[a]pyrene: Some more of the story; a letter to the editor. Toxicol. and Ind. Health 1992; 8: 213
   PubMedGoogle Scholar
• Lyte M., Blanton R., Myers M., Bick P. Effect of in vivo administration of the carcinogen benzo[a]pyrene on interleukin-2 and interleukin-3 production. Int. J. Immunopharmac. 1987; 9: 307
   PubMed Web of Science ®Google Scholar
• Pallardy M., House R., Dean J. Molecular Mechanism of 7,12-Dimethylbenz[a]anthracene-induced immunosuppression: Evidence for action via the interleukin 2 pathway. Mol. Pharmacol. 1988; 36: 128
   Web of Science ®Google Scholar
• Urso P., Gengozian N., Rossi R., Johnson R. Suppression of humoral and cell-mediated immune responses in vitro by benzo[a]pyrene. J. Immunopharm. 1986; 8: 223
   PubMedGoogle Scholar
• Urso P., Gengozian N. Alterations in the humoral immune response and tumor frequencies in mice exposed to benzo[a]pyrene and X-rays before or after Birth. J. Toxicol. Environ. Health 1982; 10: 817
   PubMed Web of Science ®Google Scholar
• Urso P., Gengozian N. Subnormal expression of cell-mediated and humoral immune responses in progeny disposed toward a high incidence of tumors after in utero exposure to benzo[a]pyrene. J. Toxicol. Environ. Health 1984; 14: 569
   PubMed Web of Science ®Google Scholar
• Kim B., Kim D., Holsapple M., Yang K. Immunosuppressive effects of 2-acetylaminofluorene and 2-aminofluorene on murine splenocytes culture. Drug and Chem. Toxicol. 1989; 12: 297
   PubMed Web of Science ®Google Scholar
• Frederick C., Mays J., Ziegler D., Guengerich F., Kadlubar F. Cytochrome P-450 and flavin-containing monooxygenase-catalyzed formation of the carcinogenic N-OH-AF and its covalent binding to nuclear DNA. Cancer Res. 1982; 42: 2671
   PubMed Web of Science ®Google Scholar
• Gelboin H. Benzo[a]pyrene metabolism, activation, and carcinogenesis: Role and regulation of mixed-function oxidases and related enzymes. Physiological Reviews 1980; 60: 1107
   PubMed Web of Science ®Google Scholar
• Guengerich F. Roles of Cytochrome P-450 enzymes in chemical carcinogenesis and cancer chemotherapy. Cancer Res. 1988; 48: 2946
   PubMed Web of Science ®Google Scholar
• Kuntzman R., Mark L., Brand M., Jacobson M, Levin M., Conney A. Metabolism of drugs and carcinogens by human liver enzymes. J. Pharmacol. Exp. Ther. 1966; 152: 152
   Web of Science ®Google Scholar
• Smith B., Springfield J., Gutmann H. Interaction of the synthetic ultimate carcinogens, N-sulfonoxy- and N-acetoxy-2-acetylaminoflourene, and of enzymatically activated N-hydroxy-2-acetylaminofluorene with nucleophiles. Carcinogenesis 1986; 7: 405
   PubMed Web of Science ®Google Scholar
• Weston A., Rowe M., Manchester D., Farmer P., Mann D., Harris C. Fluorescence and mass spectral evidence for the formation of benzo[a]pyrene anti-diol-epoxide-DNA and -hemoglobin adducts in humans. Carcinogenesis 1989; 10: 251
   PubMed Web of Science ®Google Scholar
• Heidelberger C., Gehly E., Fahl W., Jefcoate C. Microsomes, Drug Oxidations and Chemical Carcinogenesis, M Coan, A. Cooney, R. Estabrook, H. Gelboin, P. O'Brien. Academic Press, New York 1980; 1023
   Google Scholar
• Chilson O., Kelly-Chilson A. Mitogenic lectins bind to the antigen receptor on human lymphocytes. Eur. J. Immunol. 1989; 19: 389
   PubMed Web of Science ®Google Scholar
• Urso P., Zhang W., Cobb J. Immunological consequences from exposure to benzo[a]pyrene during pregnancy. Scand. J. Immunol. 1992; 36: 203
   Web of Science ®Google Scholar
• Wojdani A., Lawrence A. Alterations in cell-mediated immune functions induced in mouse splenic lymphocytes by polycyclic aromatic hydrocarbons. Cancer Res. 1984; 44: 942
   PubMed Web of Science ®Google Scholar
• Weiss A., Imboden J. Cell surface molecules and early events involved in human T lymphocyte activation. Adv. Immun. 1987; 41: 1
   PubMed Web of Science ®Google Scholar
• Shen J., Wegenke M., Wolff T. Capability of human blood cells to form the DNA adduct, C8–(N2-aminofluoreny l)-deoxyguanosine-3′-5′-diphosphate from 2-aminofluorene. Carcinogenesis 1990; 11: 1441
   PubMed Web of Science ®Google Scholar
• Borgen A., Davey H., Castagnoli N., Crocker T., Rasmussen R., Wang I. Metabolic conversion of benzo(a)pyrene by Syrian hamster liver microsomes and binding of metabolites to deoxyribonucleic acid. J. Med. Chem. 1973; 16: 502
   PubMed Web of Science ®Google Scholar
• Dean J., Luster M., Boorman G., Lauer L. Procedures available to examine the immunotoxicity of chemicals and drugs. Pharmacol. Rev. 1982; 34: 137
   PubMed Web of Science ®Google Scholar
• Blanton R., Myers M., Bick P. Modulation of immunocompetent cell populations by benzo[a]pyrene. Toxicol. Appl. Pharmacol 1988; 13: 267
   Google Scholar
• Ladics G., Kawabata T., White K. Suppression of the in vitro humoral immune response of mouse splenocytes by 7,12-dimethylbenz[a]anthracene metabolites and inhibition of immunosuppression by alpha-naphthaflavone. Toxicol. Appl. Pharmacol. 1991; 110: 31
   PubMed Web of Science ®Google Scholar
• Zhang W., Cobb J., Rodriguez J., Kirlin W., Lee M., Urso P. Benzo[a]pyrene affects functional profile of developing T-cells. 8TH INTERNATIONAL CONGRESS OF IMMUNOLOGY. 1992
   Google Scholar
• Mattano S., Weber W. Kinetics of arylamine N-acetyltransferase in tissues from rapid and slow acetylator mice. Carcinogenesis 1987; 8: 133
   PubMed Web of Science ®Google Scholar
• Chung J., Levy G., Weber W. Distribution of 2-aminofluorene and p-aminobenzoic acid N-acetyltransferase activity in C57BL/6J rapid and B6.A-Nats slow acetylator congenic mice. Drug Metab. Dispos. Biol. Fate Chem. 1993; 21: 1057
   PubMed Web of Science ®Google Scholar
• Levy G., Chung J., Weber W. 2-Aminofluorene metabolism and DNA adduct formation by mononuclear leukocytes from rapid and slow acetylator mouse strains. Carcinogenesis 1994; 15: 353
   PubMed Web of Science ®Google Scholar