Postoperative Bile Leakage Inhibits Liver Regeneration after 70% Hepatectomy in Rats

REFERENCES

• Poon RT, Lau C, Yu WC, High serum levels of vascular endothelial growth factor predict poor response to transarterial chemoembolization in hepatocellular carcinoma: a prospective study. Oncol Rep. 2004;11(5):1077–1084.
   PubMed Web of Science ®Google Scholar
• Clavien PA, Petrowsky H, DeOliveira ML, Strategies for safer liver surgery and partial liver transplantation. N Engl J Med. 2007;356(15):1545–1559.
   PubMed Web of Science ®Google Scholar
• Jarnagin WR, Gonen M, Fong Y, Improvement in perioperative outcome after hepatic resection: analysis of 1,803 consecutive cases over the past decade. Ann Surg. 2002;236(4):397–406 [discussion pp. 406–407].
   PubMed Web of Science ®Google Scholar
• Imamura H, Seyama Y, Kokudo N, One thousand fifty-six hepatectomies without mortality in 8 years. Arch Surg. 2003;138(11):1198–1206 [discussion p. 1206].
   PubMedGoogle Scholar
• Simmonds PC, Primrose JN, Colquitt JL, Surgical resection of hepatic metastases from colorectal cancer: a systematic review of published studies. Br J Cancer. 2006;94(7):982–999.
   PubMed Web of Science ®Google Scholar
• Yamashita Y, Hamatsu T, Rikimaru T, Bile leakage after hepatic resection. Ann Surg. 2001;233(1):45–50.
   Google Scholar
• Capussotti L, Ferrero A, Vigano L, Bile leakage and liver resection: where is the risk? Arch Surg. 2006;141(7):690–694 [discussion p. 695].
   Google Scholar
• Erdogan D, Busch OR, van Delden OM, Incidence and management of bile leakage after partial liver resection. Dig Surg. 2008;25(1):60–66.
   Google Scholar
• Wojcicki M, Milkiewicz P, Silva M. Biliary tract complications after liver transplantation: a review. Dig Surg. 2008;25(4):245–257.
   Google Scholar
• Mutsaerts E, Zoetmulder F, Hart A, Perioperative morbidity in hepatic surgery. Hepatogastroenterology 2007;54(74):458–462.
   Google Scholar
• Walker EM, Ellis H. Relationship of the constituents of bile to biliary peritonitis in the rat. Gut 1978;19(9):827–830.
   Google Scholar
• Andersson R, Tranberg KG, Bengmark S. Roles of bile and bacteria in biliary peritonitis. Br J Surg. 1990;77(1):36–39.
   Google Scholar
• Fukuhara K, Suzuki M, Unno M, The degree of hepatic regeneration after partial hepatectomy in rats with peritonitis and the role of lipid peroxidation. Free Radic Biol Med. 1999;26(7–8):881–886.
   Google Scholar
• Reed DNJ, Vitale GC, Wrightson WR, Decreasing mortality of bile leaks after elective hepatic surgery. Am J Surg. 2003;185(4):316–318.
   Google Scholar
• Seehofer D, Stockmann M, Schirmeier A, Intraabdominal bacterial infections significantly alter regeneration and function of the liver in a rat model of major hepatectomy. Langenbecks Arch Surg. 2007;392(3):273–284.
   Google Scholar
• Seehofer D, Rayes N, Schiller R, Probiotics partly reverse increased bacterial translocation after simultaneous liver resection and colonic anastomosis in rats. J Surg Res. 2004;117(2):262–271.
   Google Scholar
• MacDonald RA, Rogers AE, Pechet G. Regeneration of the liver: relation of regenerative response to size of partial hepatectomy. Lab Invest. 1962;11:544–548.
   Google Scholar
• Webber EM, Bruix J, Pierce RH, Tumor necrosis factor primes hepatocytes for DNA replication in the rat. Hepatology 1998;28(5):1226–1234.
   Google Scholar
• Taub R. Liver regeneration: from myth to mechanism. Nat Rev Mol Cell Biol. 2004;5(10):836–847.
   PubMed Web of Science ®Google Scholar
• Fausto N, Campbell JS, Riehle KJ. Liver regeneration. Hepatology 2006;43(2 Suppl. 1):S45–S53.
   PubMed Web of Science ®Google Scholar
• Bautista AP, Schuler A, Spolarics Z, Tumor necrosis factor-alpha stimulates superoxide anion generation by perfused rat liver and Kupffer cells. Am J Physiol. 1991;261(6 Pt 1):G891–G895.
   Google Scholar
• Schwabe RF, Brenner DA. Mechanisms of liver injury. I. TNF-alpha-induced liver injury: role of IKK, JNK, and ROS pathways. Am J Physiol Gastrointest Liver Physiol. 2006;290(4):G583–G589.
   PubMed Web of Science ®Google Scholar
• Beyer TA, Xu W, Teupser D, Impaired liver regeneration in Nrf2 knockout mice: role of ROS-mediated insulin/IGF-1 resistance. EMBO J. 2008;27(1):212–223.
   Google Scholar
• Meijer DK, Weert B, Vermeer GA. Pharmacokinetics of biliary excretion in man. VI. Indocyanine green. Eur J Clin Pharmacol. 1988;35(3):295–303.
   Google Scholar
• Paumgartner G, Probst P, Kraines R, Kinetics of indocyanine green removal from the blood. Ann N Y Acad Sci. 1970;170(1):134–147.
   Google Scholar
• Mann DV, Lam WW, Hjelm NM, Human liver regeneration: hepatic energy economy is less efficient when the organ is diseased. Hepatology 2001;34(3):557–565.
   Google Scholar
• Mann DV, Lam WW, Hjelm NM, Metabolic control patterns in acute phase and regenerating human liver determined in vivo by 31-phosphorus magnetic resonance spectroscopy. Ann Surg. 2002;235(3):408–416.
   Google Scholar
• Corbin IR, Buist R, Volotovskyy V, Regenerative activity and liver function following partial hepatectomy in the rat using (31)P-MR spectroscopy. Hepatology 2002;36(2):345–353.
   Google Scholar
• Ueda J, Chijiiwa K, Nakano K, Lack of intestinal bile results in delayed liver regeneration of normal rat liver after hepatectomy accompanied by impaired cyclin E-associated kinase activity. Surgery 2002;131(5):564–573.
   Google Scholar
• Huang W, Ma K, Zhang J, Nuclear receptor-dependent bile acid signaling is required for normal liver regeneration. Science 2006;312(5771):233–236.
   PubMed Web of Science ®Google Scholar
• Wang H, Chen J, Hollister K, Endogenous bile acids are ligands for the nuclear receptor FXR/BAR. Mol Cell. 1999;3(5):543–553.
   PubMed Web of Science ®Google Scholar
• Makishima M, Okamoto AY, Repa JJ, Identification of a nuclear receptor for bile acids. Science 1999;284(5418):1362–1365.
   PubMed Web of Science ®Google Scholar
• Chamuleau RA, Aronson DC, Frederiks WM, Liver regeneration after partial hepatectomy in rats with defective bilirubin conjugation or biliary excretion. Dig Dis Sci. 1991;36(4):510–512.
   Google Scholar
• Alexandris IH, Assimakopoulos SF, Vagianos CE, Oxidative state in intestine and liver after partial hepatectomy in rats. Effect of bombesin and neurotensin. Clin Biochem. 2004;37(5):350–356.
   Google Scholar
• Xu CP, Liu J, Liu JC, Dynamic changes and mechanism of intestinal endotoxemia in partially hepatectomized rats. World J Gastroenterol. 2007;13(26):3592–3597.
   Google Scholar
• Boermeester MA, Straatsburg IH, Houdijk AP, Endotoxin and interleukin-1 related hepatic inflammatory response promotes liver failure after partial hepatectomy. Hepatology 1995;22(5):1499–1506.
   PubMed Web of Science ®Google Scholar
• Straatsburg IH, Boermeester MA, Houdijk AP, Endotoxin- and cytokine-mediated effects on liver cell proliferation and lipid metabolism after partial hepatectomy: a study with recombinant N-terminal bactericidal/ permeability-increasing protein and interleukin-1 receptor antagonist. J Pathol. 1996;179(1):100–105.
   Google Scholar
• Helling TS, Dhar A, Helling TS, Partial hepatectomy with or without endotoxin does not promote apoptosis in the rat liver. J Surg Res. 2004;116(1):1–10.
   Google Scholar
• Borowiak M, Garratt AN, Wustefeld T, Met provides essential signals for liver regeneration. Proc Natl Acad Sci U S A. 2004;101(29):10608–10613.
   PubMed Web of Science ®Google Scholar
• Huh CG, Factor VM, Sanchez A, Hepatocyte growth factor/c-met signaling pathway is required for efficient liver regeneration and repair. Proc Natl Acad Sci U S A. 2004;101(13):4477–4482.
   PubMed Web of Science ®Google Scholar
• Paranjpe S, Bowen WC, Bell AW, Cell cycle effects resulting from inhibition of hepatocyte growth factor and its receptor c-Met in regenerating rat livers by RNA interference. Hepatology 2007;45(6):1471–1477.
   Google Scholar
• Sakon M, Kita Y, Yoshida T, Plasma hepatocyte growth factor levels are increased in systemic inflammatory response syndrome. Surg Today 1996;26(4):236–241.
   Google Scholar
• Masson S, Daveau M, Francois A, Up-regulated expression of HGF in rat liver cells after experimental endotoxemia: a potential pathway for enhancement of liver regeneration. Growth Factors 2001;18(4):237–250.
   PubMed Web of Science ®Google Scholar
• Rampino T, Cancarini G, Gregorini M, Hepatocyte growth factor/scatter factor released during peritonitis is active on mesothelial cells. Am J Pathol. 2001;159(4):1275–1285.
   PubMed Web of Science ®Google Scholar
• Mizuguchi T, Kamohara Y, Hui T, Regulation of c-met expression in rats with acute hepatic failure. J Surg Res. 2001;99(2):385–396.
   Google Scholar