A Comparative Investigation of the Analgesic Effects of Metamizole and Paracetamol in Rats

REFERENCES

• Milton L. Principles of Pain and Pain Management. New York, NY: Mosby; 2003.
   Google Scholar
• Dahi-Taleghani M, Fazli B, Ghasemi M, et al. Effect of intravenous patient controlled ketamine analgesiaon postoperative pain in opium abusers. Anesth Pain Med. 2014;4: e14129.
   Google Scholar
• Veiga AP, Duarte ID, Avila MN, et al. Prevention by celecoxib of secondary hyperalgesia induced by formalin in rats. Life Sci. 2004;75:2807–2817.
   Google Scholar
• Carreira EU, Carregaro V, Teixeira MM, et al. Neutrophils recruited by CXCR1/2 signalling mediate post-incisional pain. Eur J Pain. 2013;17:654–663.
   Google Scholar
• Kara C, Suleyman H, Tezel A, et al. Evaluation of pain levels after Nd: YAG laser and scalpel incisions: an experimental study in rats. Photomed Laser Surg. 2010;28:635–638.
   PubMedGoogle Scholar
• Anand R, Kaithwas G. Anti-inflammatory potential of alpha-linolenic acid mediated through selective COX inhibition: computational and experimental data. Inflammation 2014;37:1297–1306.
   PubMed Web of Science ®Google Scholar
• Tamaddonfard E, Farshid AA, Eghdami K, et al. Comparison of the effects of crocin, safranal and diclofenac on local inflammation and inflammatory pain responses induced by carrageenan in rats. Pharmacol Rep. 2013;65:1272–1280.
   Google Scholar
• Sadeghi H, Hajhashemi V, Minaiyan M, et al. Further studies on anti-inflammatory activity of maprotiline in carrageenan-induced paw edema in rat. Int Immunopharmacol. 2013;15:505–510.
   PubMed Web of Science ®Google Scholar
• Eltzschig HK, Collard CD. Vascular ischaemia and reperfusion injury. Br Med Bull. 2004;70:71–86.
   PubMed Web of Science ®Google Scholar
• Miettinen S, Fusco FR, Yrjanheikki J, et al. Spreading depression and focal brain ischemia induce cyclooxygenase-2 in cortical neurons through N-methyl-D-aspartic acid-receptors and phospholipase A2. Proc Natl Acad Sci USA. 1997;94:6500–6505.
   PubMed Web of Science ®Google Scholar
• Brogden RN. Pyrazolone derivatives. Drugs 1986;32(Suppl 4):60–70.
   Google Scholar
• Bannwarth B, Pehourcq F. Pharmacologic basis for using paracetamol: pharmacokinetic and pharmacodynamic issues. Drugs 2003;(63 Spec No 2):5–13.
   Google Scholar
• Giri AK, Mukhopadhyay A. Mutagenicity assay in Salmonella and in vivo sister chromatid exchange in bone marrow cells of mice for four pyrazolone derivatives. Mutat Res. 1998;420:15–25.
   PubMed Web of Science ®Google Scholar
• Woodbury D, Fingl, E. Analgesic, antipyretic, anti-inflammatory agents and drugs employed in the therapy of gout. In: The Pharmacological Basis of Therapeutics. Gilman LSGA, ed. New York, NY: Macmillan; 1975: 334–339.
   Google Scholar
• Costa D, Gomes A, Lima JL, Fernandes E. Singlet oxygen scavenging activity of non-steroidal anti-inflammatory drugs. Redox Rep. 2008;13:153–160.
   PubMed Web of Science ®Google Scholar
• Chandrasekharan NV, Dai H, Roos KL, et al. COX-3, a cyclooxygenase-1 variant inhibited by acetaminophen and other analgesic/antipyretic drugs: cloning, structure, and expression. Proc Natl Acad Sci USA. 2002;99:13926–13931.
   PubMed Web of Science ®Google Scholar
• Cadirci E, Suleyman H, Hacimuftuoglu A, et al. Indirect role of beta2-adrenergic receptors in the mechanism of analgesic action of nonsteroidal anti-inflammatory drugs. Crit Care Med. 2010;38:1860–1867.
   Google Scholar
• Ohkawa H, Ohishi N, Yagi K. Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction. Anal Biochem. 1979;95:351–358.
   PubMed Web of Science ®Google Scholar
• Sedlak J, Lindsay RH. Estimation of total, protein-bound, and nonprotein sulfhydryl groups in tissue with Ellman's reagent. Anal Biochem. 1968;25:192–205.
   PubMed Web of Science ®Google Scholar
• Hernandez-Palazon J, Tortosa JA, Martinez-Lage JF, Perez-Flores D. Intravenous administration of propacetamol reduces morphine consumption after spinal fusion surgery. Anesth Analg. 2001;92:1473–1476.
   PubMed Web of Science ®Google Scholar
• Lerea LS, Carlson NG, Simonato M, et al. Prostaglandin F2alpha is required for NMDA receptor-mediated induction of c-fos mRNA in dentate gyrus neurons. J Neurosci. 1997;17:117–124.
   Google Scholar
• Ancian P, Lambeau G, Mattei MG, Lazdunski M. The human 180-kDa receptor for secretory phospholipases A2. Molecular cloning, identification of a secreted soluble form, expression, and chromosomal localization. J Biol Chem. 1995;270:8963–8970.
   PubMed Web of Science ®Google Scholar
• Rezende RM, Franca DS, Menezes GB, et al. Different mechanisms underlie the analgesic actions of paracetamol and dipyrone in a rat model of inflammatory pain. Br J Pharmacol. 2008;153:760–768.
   Google Scholar
• Sauzem PD, Sant'Anna Gda S, Machado P, et al. Effect of 5-trifluoromethyl-4,5-dihydro-1H-pyrazoles on chronic inflammatory pain model in rats. Eur J Pharmacol. 2009;616:91–100.
   Google Scholar
• Shih CM, Cheng SN, Wong CS, et al. Anti-inflammatory and antihyperalgesic activity of C-phycocyanin. Anesth Analg. 2009;108:1303–1310.
   PubMed Web of Science ®Google Scholar
• Marzocco S, Di Paola R, Serraino I, et al. Effect of methylguanidine in carrageenan-induced acute inflammation in the rats. Eur J Pharmacol. 2004;484:341–350.
   PubMed Web of Science ®Google Scholar
• Gilligan JP, Lovato SJ, Erion MD, Jeng AY. Modulation of carrageenan-induced hind paw edema by substance P. Inflammation 1994;18:285–292.
   PubMed Web of Science ®Google Scholar
• Prianti AC, Jr., Silva JA, Jr., Dos Santos RF, et al. Low-level laser therapy (LLLT) reduces the COX-2 mRNA expression in both subplantar and total brain tissues in the model of peripheral inflammation induced by administration of carrageenan. Lasers Med Sci. 2014.
   Google Scholar
• Posadas I, Bucci M, Roviezzo F, et al. Carrageenan-induced mouse paw oedema is biphasic, age-weight dependent and displays differential nitric oxide cyclooxygenase-2 expression. Br J Pharmacol. 2004;142:331–338.
   PubMed Web of Science ®Google Scholar
• Nonato FR, Santana DG, de Melo FM, et al. Anti-inflammatory properties of rose oxide. Int Immunopharmacol. 2012;14:779–784.
   Google Scholar
• Kisaoglu A, Borekci B, Yapca OE, et al. Tissue damage and oxidant/antioxidant balance. Eurasian J Med. 2013;45:47–49.
   PubMedGoogle Scholar
• El-Shitany NA, El-Masry SA, El-Ghareib MA, El-Desoky K. Thioctic acid protects against carrageenan-induced acute inflammation in rats by reduction in oxidative stress, downregulation of COX-2 mRNA and enhancement of IL-10 mRNA. Fundam Clin Pharmacol. 2010;24: 91–99.
   Google Scholar