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Inhalation Toxicology
International Forum for Respiratory Research
Volume 22, 2010 - Issue 10
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Research Article

Gene expression profile in circulating mononuclear cells after exposure to ultrafine carbon particles

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Pages 835-846 | Received 21 Jan 2010, Accepted 13 Apr 2010, Published online: 27 May 2010

References

  • Abbas A, Grant PJ, Kearney MT. 2008. Role of IGF-1 in glucose regulation and cardiovascular disease. Expert Rev Cardiovasc Ther 6:1135–1149.
  • Anderson PJ, Wilson JD, Hiller FC. 1990. Respiratory tract deposition of ultrafine particles in subjects with obstructive or restrictive lung disease. Chest 97:1115–1120.
  • Bateson TF, Schwartz J. 2004. Who is sensitive to the effects of particulate air pollution on mortality? A case-crossover analysis of effect modifiers. Epidemiology 15:143–149.
  • Brook RD. 2008. Cardiovascular effects of air pollution. Clin Sci 115:175–187.
  • Conti E, Pitocco D, Capoluongo E, Zuppi C, Ghirlanda G, Crea F, Andreotti F. 2003. IGF-1 and macrovascular complications of diabetes: alternative interpretations of recently published data. Diabetes Care 26:1653–4; author reply 1654.
  • Dubowsky SD, Suh H, Schwartz J, Coull BA, Gold DR. 2006. Diabetes, obesity, and hypertension may enhance associations between air pollution and markers of systemic inflammation. Environ Health Perspect 114:992–998.
  • Edgar R, Domrachev M, Lash AE. 2002. Gene Expression Omnibus: NCBI gene expression and hybridization array data repository. Nucleic Acids Res 30:207–210.
  • Frampton MW. 2001. Systemic and cardiovascular effects of airway injury and inflammation: ultrafine particle exposure in humans. Environ Health Perspect 109 Suppl 4:529–532.
  • Frampton MW, Stewart JC, Oberdörster G, Morrow PE, Chalupa D, Pietropaoli AP, Frasier LM, Speers DM, Cox C, Huang LS, Utell MJ. 2006. Inhalation of ultrafine particles alters blood leukocyte expression of adhesion molecules in humans. Environ Health Perspect 114:51–58.
  • Frampton MW, Utell MJ, Zareba W, Oberdörster G, Cox C, Huang LS, Morrow PE, Lee FE, Chalupa D, Frasier LM, Speers DM, Stewart J. 2004. Effects of exposure to ultrafine carbon particles in healthy subjects and subjects with asthma. Res Rep Health Eff Inst 126:1–47; discussion 49.
  • Hathout EH, Beeson WL, Nahab F, Rabadi A, Thomas W, Mace JW. 2002. Role of exposure to air pollutants in the development of type 1 diabetes before and after 5 yr of age. Pediatr Diabetes 3:184–188.
  • Hochberg Y, Benjamini Y. 1990. More powerful procedures for multiple significance testing. Stat Med 9:811–818.
  • Ibald-Mulli A, Wichmann HE, Kreyling W, Peters A. 2002. Epidemiological evidence on health effects of ultrafine particles. J Aerosol Med 15:189–201.
  • Li N, Alam J, Venkatesan MI, Eiguren-Fernandez A, Schmitz D, Di Stefano E, Slaughter N, Killeen E, Wang X, Huang A, Wang M, Miguel AH, Cho A, Sioutas C, Nel AE. 2004. Nrf2 is a key transcription factor that regulates antioxidant defense in macrophages and epithelial cells: protecting against the proinflammatory and oxidizing effects of diesel exhaust chemicals. J Immunol 173:3467–3481.
  • McDonald JD, Powell QH, Bowen LE, Mauderly JL. 2001. Organic carbon content of aerosols produced from a Palas carbon generation system. Toxicologist 60:430.
  • Moses AC. 2005. Insulin resistance and type 2 diabetes mellitus: is there a therapeutic role for IGF-1? Endocr Dev 9:121–134.
  • Nemmar A, Hoet PH, Vanquickenborne B, Dinsdale D, Thomeer M, Hoylaerts MF, Vanbilloen H, Mortelmans L, Nemery B. 2002. Passage of inhaled particles into the blood circulation in humans. Circulation 105:411–414.
  • Nemmar A, Vanbilloen H, Hoylaerts MF, Hoet PH, Verbruggen A, Nemery B. 2001. Passage of intratracheally instilled ultrafine particles from the lung into the systemic circulation in hamster. Am J Respir Crit Care Med 164:1665–1668.
  • O’Neill MS, Veves A, Sarnat JA, Zanobetti A, Gold DR, Economides PA, Horton ES, Schwartz J. 2007. Air pollution and inflammation in type 2 diabetes: a mechanism for susceptibility. Occup Environ Med 64:373–379.
  • Oberdorster G, Gelein RM, Ferin J, Weiss B. 1995. Association of particulate air pollution and acute mortality: involvement of ultrafine particles? Inhal Toxicol 7:111–124.
  • Oberdörster G, Sharp Z, Atudorei V, Elder A, Gelein R, Kreyling W, Cox C. 2004. Translocation of inhaled ultrafine particles to the brain. Inhal Toxicol 16:437–445.
  • Oberdörster G, Sharp Z, Atudorei V, Elder A, Gelein R, Lunts A, Kreyling W, Cox C. 2002. Extrapulmonary translocation of ultrafine carbon particles following whole-body inhalation exposure of rats. J Toxicol Environ Health Part A 65:1531–1543.
  • Oberdörster G, Utell MJ. 2002. Ultrafine particles in the urban air: to the respiratory tract–and beyond? Environ Health Perspect 110:A440–A441.
  • Penttinen P, Timonen KL, Tiittanen P, Mirme A, Ruuskanen J, Pekkanen J. 2001. Ultrafine particles in urban air and respiratory health among adult asthmatics. Eur Respir J 17:428–435.
  • Peretz A, Peck EC, Bammler TK, Beyer RP, Sullivan JH, Trenga CA, Srinouanprachnah S, Farin FM, Kaufman JD. 2007. Diesel exhaust inhalation and assessment of peripheral blood mononuclear cell gene transcription effects: an exploratory study of healthy human volunteers. Inhal Toxicol 19:1107–1119.
  • Peters A, Wichmann HE, Tuch T, Heinrich J, Heyder J. 1997. Respiratory effects are associated with the number of ultrafine particles. Am J Respir Crit Care Med 155:1376–1383.
  • Pietropaoli AP, Frampton MW, Hyde RW, Morrow PE, Oberdörster G, Cox C, Speers DM, Frasier LM, Chalupa DC, Huang LS, Utell MJ. 2004. Pulmonary function, diffusing capacity, and inflammation in healthy and asthmatic subjects exposed to ultrafine particles. Inhal Toxicol 16 Suppl 1:59–72.
  • Schneider A, Neas L, Herbst MC, Case M, Williams RW, Cascio W, Hinderliter A, Holguin F, Buse JB, Dungan K, Styner M, Peters A, Devlin RB. 2008. Endothelial dysfunction: associations with exposure to ambient fine particles in diabetic individuals. Environ Health Perspect 116:1666–1674.
  • Seaton A, MacNee W, Donaldson K, Godden D. 1995. Particulate air pollution and acute health effects. Lancet 345:176–178.
  • Shah AP, Pietropaoli AP, Frasier LM, Speers DM, Chalupa DC, Delehanty JM, Huang LS, Utell MJ, Frampton MW. 2008. Effect of inhaled carbon ultrafine particles on reactive hyperemia in healthy human subjects. Environ Health Perspect 116:375–380.
  • Sun Q, Yue P, Deiuliis JA, Lumeng CN, Kampfrath T, Mikolaj MB, Cai Y, Ostrowski MC, Lu B, Parthasarathy S, Brook RD, Moffatt-Bruce SD, Chen LC, Rajagopalan S. 2009. Ambient air pollution exaggerates adipose inflammation and insulin resistance in a mouse model of diet-induced obesity. Circulation 119:538–546.
  • Whitsel EA, Quibrera PM, Christ SL, Liao D, Prineas RJ, Anderson GL, Heiss G. 2009. Heart rate variability, ambient particulate matter air pollution, and glucose homeostasis: the environmental epidemiology of arrhythmogenesis in the women’s health initiative. Am J Epidemiol 169:693–703.
  • Wichmann HE, Spix C, Tuch T, Wölke G, Peters A, Heinrich J, Kreyling WG, Heyder J. 2000. Daily mortality and fine and ultrafine particles in Erfurt, Germany part I: role of particle number and particle mass. Res Rep Health Eff Inst 98:5–86; discussion 87.
  • Xia T, Kovochich M, Nel A. 2006. The role of reactive oxygen species and oxidative stress in mediating particulate matter injury. Clin Occup Environ Med 5:817–836.
  • Zanobetti A, Schwartz J. 2002. Cardiovascular damage by airborne particles: are diabetics more susceptible? Epidemiology 13:588–592.

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