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Inhalation Toxicology
International Forum for Respiratory Research
Volume 23, 2011 - Issue 1
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Original Article

Deposition of naphthalene and tetradecane vapors in models of the human respiratory system

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Pages 44-57 | Received 23 Apr 2010, Accepted 11 Nov 2010, Published online: 12 Jan 2011

References

  • Abdo KM, Grumbein S, Chou BJ, Herbert R. 2001. Toxicity and carcinogenicity study in F344 rats following 2 years of whole-body exposure to naphthalene vapors. Inhal Toxicol 13:931–950.
  • Agency for Toxic Substances and Disease Registry (ATSDR). 2005. Toxicological Profile for Naphthalene, 1-Methylnaphthalene, and 2-Methylnaphthalene. US Department of Health and Human Services.
  • Aharonson EF, Menkes H, Gurtner G, Swift DL, Proctor DF. 1974. Effect of respiratory airflow rate on removal of soluble vapors by the nose. J Appl Physiol 37:654–657.
  • Ambrose D, Lawrenson IJ, Sprake CHS. 1975. The vapor pressure of naphthalene. J Chem Thermodyn 7:1173–1176.
  • Asgharian B, Hofman W, Bergmann R. 2001. Particle deposition in a multiple-path model of the human lung. Aerosol Sci Technol 34:332–339.
  • BallCG, Uddin M, Pollard A. 2008. High resolution turbulence modelling of airflow in an idealised human extra-thoracic airway. Computers Fluids 37:943–964.
  • Bui TD, Dabdub D, George SC. 1998. Modeling bronchial circulation with application to soluble gas exchange: description and sensitivity analysis. J Appl Physiol 84:2070–2088.
  • Bush ML, Frederick CB, Kimbell JS, Ultman JS. 1998. A CFD–PBPK hybrid model for simulating gas and vapor uptake in the rat nose. Toxicol Appl Pharmacol 150:133–145.
  • Campbell JL Jr, Fisher JW. 2007. A PBPK modeling assessment of the competitive metabolic interactions of JP-8 vapor with two constituents, m-xylene and ethylbenzene. Inhal Toxicol 19:265–273.
  • Cheng KH, Cheng YS, Yeh HC, Swift DL. 1995. Deposition of ultrafine aerosols in the head airways during natural breathing and during simulated breath-holding using replicate human upper airway casts. Aerosol Sci Technol 23:465–474.
  • Choi JI, Kim CS. 2007. Mathematical analysis of particle deposition in human lungs: an improved single path transport model. Inhal Toxicol 19:925–939.
  • Davidson MR, Schroter R. 1983. A theoretical model of absorption of gases by the bronchial wall. J Fluid Mech 129:313–335.
  • George SC, Babb AL, Hlastala MP. 1995. Modeling the concentration of ethanol in the exhaled breath following pretest breathing maneuvers. Ann Biomed Eng 23:48–60.
  • Grotberg JB. 2001. Respiratory fluid mechanics and transport processes. Annu Rev Biomed Eng 3:421–457.
  • Grotberg JB, Sheth BV, Mockros LF. 1990. An analysis of pollutant gas transport and absorption in pulmonary airways. J Biomech Eng 112:168–176.
  • Gustafson JB, Tell JG, Orem D. 1997. Selection of Representative TPH Fractions Based on Fate and Transport Consideration. Amherst, MA: Amherst Scientific Publishers.
  • Horsfield K, Dart G, Olson DE, Filley GF, Cumming G. 1971. Models of the human bronchial tree. J Appl Physiol 31:207–217.
  • IARC. 2002. Naphthalene. IARC monographs on the evaluation of the carcinogenic risk of chemicals to humans. IARC Monogr Eval Carcinog Risks Hum 82:367–435.
  • Keyhani K, Scherer PW, Mozell MM. 1997. A numerical model of nasal odorant transport for the analysis of human olfaction. J Theor Biol 186:279–301.
  • Kleinstreuer C, Zhang Z. 2010. Airflow and particle transport in the human respiratory system. Annu Rev Fluid Mech 42:301–334.
  • Kleinstreuer C, Zhang Z. 2009. An adjustable triple-bifurcation unit model for air–particle flow simulations in human tracheobronchial airways. J Biomech Eng 131:021007.
  • Li W, Xiong JQ, Cohen BS. 1998. The deposition of unattached radon progeny in a tracheobronchial cast as measured with iodine vapor. Aerosol Sci Technol 28:502–510.
  • Li Z, Kleinstreuer C, Zhang Z. 2007. Particle deposition in the human tracheobronchial airways due to transient inspiratory flow patterns. J Aerosol Sci 38:625–644.
  • Long PH, Herbert RA, Peckham JC, Grumbein SL, Shackelford CC, Abdo K. 2003. Morphology of nasal lesions in F344/N rats following chronic inhalation exposure to naphthalene vapors. Toxicol Pathol 31:655–664.
  • Martin SA, Tremblay RT, Brunson KF, Kendrick C, Fisher JW. 2010. Characterization of a nose-only inhalation exposure system for hydrocarbon mixtures and jet fuels. Inhal Toxicol 22:382–393.
  • Merrill EA, Gearhart JM, Sterner TR, Robinson PJ. 2008. Improved predictive model for n-decane kinetics across species, as a component of hydrocarbon mixtures. Inhal Toxicol 20:851–863.
  • Morris JB, Buckpitt AR. 2009. Upper respiratory tract uptake of naphthalene. Toxicol Sci 111:383–391.
  • Morris JB, Hubbs AF. 2009. Inhalation dosimetry of diacetyl and butyric acid, two components of butter flavoring vapors. Toxicol Sci 108:173–183.
  • National Council on Radiation Protection and Measurements (NCRP). 1997. Deposition, Retention, and Dosimetry of Inhaled Radioactive Substances, Report No. 125, National Council on Radiation Protection and Measurements, Bethesda, MD.
  • National Institute for Public Health and the Environment (RIVM). 2002. Multiple Path Particle Dosimetry Model (MPPD v 1.0): A Model for Human and Rat Airway Particle Dosimetry. Bilthoven, The Netherlands. RIVA Report 650010030.
  • National Research Council (NRC) Board on Environmental Studies of Toxicology (BEST). 2003. Toxicologic Assessment of Jet-Propulsion Fuel-8. Washington, DC: National Academy Press.
  • NTP. 1992. Toxicology and Carcinogenesis Studies of Naphthalene (CAS No. 91-20-3) in B6C3F1 Mice (Inhalation Studies). Research Triangle Park, NC: U.S. Department of Health and Human Services, Public Health Service, National Institutes of Health. National Toxicology Program. NIH Publication No. 92-3141. Technical Report Series No. 410.
  • NTP. 2000. Toxicology and Carcinogenesis Studies of Naphthalene (CAS No. 91-20-3) in F344/N Rats (Inhalation Studies). National Toxicology Program. NTP TR 500, NIH Publ. No. 01-4434.
  • Perleberg UR, Keys DA, Fisher JW. 2004. Development of a physiologically based pharmacokinetic model for decane, a constituent of jet propellent-8. Inhal Toxicol 16:771–783.
  • Raabe OG, Yeh HC, Schum GM, Phalen RF. 1976. Tracheobronchial Geometry: Human, Dog, Rat, Hamster, LF-53. Lovelace Foundation Report, Albuquerque, New Mexico.
  • Ritchie G, Still K, Rossi J 3rd, Bekkedal M, Bobb A, Arfsten D. 2003. Biological and health effects of exposure to kerosene-based jet fuels and performance additives. J Toxicol Environ Health B Crit Rev 6:357–451.
  • Savino R, Fico S. 2004. Transient Marangoni convection in hanging evaporating drops. Physics Fluids 16:3738–3754.
  • Shi H, Kleinstreuer C, Zhang Z. 2008. Dilute suspension flow with nanoparticle deposition in a representative nasal airway model. Physics Fluids 20:013301.
  • Swift DL, Montassier N, Hopke PK, Karpenhayes K, Cheng YS, SuYF, YehHC, Strong JC. 1992. Inspiratory deposition of ultrafine particles in human nasal replicate cast. J Aerosol Sci 23:65–72.
  • Swift DL, Strong JC. 1996. Nasal deposition of ultrafine Po-218 aerosols in human subjects. J Aerosol Sci 27:1125–1132.
  • Tian G, Longest PW. 2010. Transient absorption of inhaled vapors into a multilayer mucus–tissue–blood system. Ann Biomed Eng 38:517–536.
  • Widdicombe J. 1997. Airway and alveolar permeability and surface liquid thickness: theory. J Appl Physiol 82:3–12.
  • Xi JX, LongestPW. 2008. Numerical predictions of submicrometer aerosol deposition in the nasal cavity using a novel drift flux approach. Int J Heat Mass Transfer 51:5562–5577.
  • Zeiger E. 2005. AFOSR JP-8 Jet Fuel Toxicology Workshop. Summary Report prepared for Dr. W. Kozumbo (AFOSR, Arlington, VA), Errol Zeiger Consulting, Chapel Hill, NC.
  • Zhang Y, Finlay WH. 2005. Measurement of the effect of cartilaginous rings on particle deposition in a proximal lung bifurcation model. Aerosol Sci Technol 39:394–399.
  • Zhang Z, Kleinstreuer C. 2010. Laminar-to-turbulent fluid–nanoparticle dynamics simulations: model comparisons and nanoparticle-deposition applications. International Journal for Numerical Methods in Biomedical Engineering, in review.
  • ZhangZ, Kleinstreuer C. 2003. Species heat and mass transfer in a human upper airway model. Int J Heat Mass Transfer 46:4755–4768.
  • Zhang Z, Kleinstreuer C, Kim CS. 2008. Airflow and nanoparticle deposition in a 16-generation tracheobronchial airway model. Ann Biomed Eng 36:2095–2110.
  • Zhang Z, Kleinstreuer C, Kim CS. 2006. Transport and uptake of MTBE and ethanol vapors in a human upper airway model. Inhal Toxicol 18:169–184.
  • Zhao K, Scherer PW, Hajiloo SA, Dalton P. 2004. Effect of anatomy on human nasal air flow and odorant transport patterns: implications for olfaction. Chem Senses 29:365–379.

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