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Inhalation Toxicology
International Forum for Respiratory Research
Volume 27, 2015 - Issue 9
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Research Article

Development of a chronic inhalation reference value for hexamethylenediamine using an exposure model based on the dihydrochloride salt

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Pages 440-449 | Received 18 May 2015, Accepted 26 Jun 2015, Published online: 27 Jul 2015

References

  • American Conference for Governmental and Industrial Hygienist (ACGIH). (2001). 1,6-Hexanediamine. In: Documentation of the threshold limit values and biological exposure indices, 7th ed. American Conference of Government Industrial Hygienists, Cincinnati, OH
  • Asgharian B, Price OT, Oldham M, et al. (2014). Computational modeling of nanoscale and microscale particle deposition, retention and dosimetry in the mouse respiratory tract. Inhal Toxicol 26:829–42
  • Capobianco T, Hildebrand SM, Honeycutt M, et al. (2013). Impact of three interactive Texas state regulatory programs to decrease ambient air toxic levels. J Air Waste Manage Assoc 63:507–20
  • Ceresa C. (1948). Observations on the picture of blood constitution in some workers employed in preparation of nylon. Med Lavoro 39:162–5 (In Italian, English Abstr.) (cited in NTP 1993)
  • David RM, Heck Hd'A. (1983). Localization of 1,6-[14C]diaminohexane (HMDA) in the prostate and the effects of HMDA on early gestation in Fischer-344 rats. Toxicol Lett 17:49--55
  • de Winter-Sorkina R, Cassee FR. (2002). From concentration to dose: factors influencing airborne particulate matter deposition in humans and rats. RIVM Report 650010031. Available from: http://rivm.openrepository.com/rivm/bitstream/10029/9272/1/650010031.pdf. [Last accessed: 14 Jul 2015]
  • Erranguntla NE, Grant RL. (2015). Health- and vegetative-based effect screening values for ethylene, Chemico-Biol Interact. [Epub ahead of print]. doi: http://dx.doi.org/10.1016/j.cbi.2015.02.010
  • Gallo G, Ghiringhelli L. (1958). Occupational exposure to hexamethylenediamine. Med Lavoro 49:683--9 (In Italian, English Abstr.) (cited in NTP 1993)
  • Grant RL, Haney J, Curry AL, Honeycutt M. (2010). A chronic reference value for 1,3-butadiene based on an updated noncancer toxicity assessment. J Toxicol Environ Health Part B 13:460–75
  • Grant RL, Santos SL, Dourson ML, et al. (2015). Unpacking toxicity assessments to understand and improve confidence. In: The Toxicologist: Supplement to Toxicological Sciences, 144, Society of Toxicology, 2015, Abstract no. 873. Available from: http://blog.americanchemistry.com/wp-content/uploads/2015/04/Grant-SOT-2015-Final.pdf. [Last accessed: 14 Jul 2015]
  • Hébert CD, Elwell MR, Travlos GS, et al. (1993). Inhalation toxicity of 1,6-hexanediamine dihydrochloride in F344/N rats and B6C3F1 mice. Fundam Appl Toxicol 20:348–59
  • Johannsen FR, Levinskas GJ. (1987). Toxicological profile of orally administered 1,6-hexane diamine in the rat. J Appl Toxicol 7:259–63 (cited in Kennedy 2005)
  • Johannsen FR, Levinskas GJ, Ben-Dyke R, Hogan GK. (1987). Subchronic inhalation toxicity of hexamethylenediamine in rats. Fundam Appl Toxicol 9:504–11
  • Kennedy Jr GL. (2005). Toxicity of hexamethylenediamine. Drug Chem Toxicol 28:15–33
  • Kulakov AE. (1965). The effect of small concentrations of hexamethylenediamine on experimental animals under conditions of chronic inhalation poisoning. Gig Sani 30:15–20 (In Russian, English Abstr.) (cited in NTP 1993 and Kennedy 2005)
  • Manen C-A, Hood RD, Farin J. (1983). Ornithine decarboxylase inhibitors and fetal growth retardation in mice. Teratology 28:237--42 (cited in Kennedy 2005)
  • Monsanto Chemical Co. (nd). (cited in Kennedy 2005)
  • Monsanto Company. (1990). Two generation reproduction study in rat. NTIS/FYI-OTS0526381-1. Springfield, VA: U.S. Department of Commerce
  • National Research Council (NRC). (1983). Risk assessment in the federal government. Washington, DC: National Research Council, National Academy Press
  • National Research Council (NRC). (1994). Science and judgment in risk assessment. Washington, DC: National Research Council, National Academy Press
  • National Research Council (NRC). (2001). Standing operating procedures for developing acute exposure guideline levels for hazardous chemicals. Washington, DC: National Research Council, National Academy Press
  • National Toxicology Program (NTP). (1993). NTP Technical Report on toxicity studies of 1,6-hexanediamine dihydrochloride, CAS No. 6055-52-3. Research Triangle Park, NC: U.S. Department of Health and Human Services, Public Health Service, National Institutes of Health. NTP Toxicity Report Series Number 24
  • National Science Foundation (NSF) International. (2006). Hexamethylenediamine. CAS # 124-09-4. Oral Risk Assessment Document. July. Available for a fee at http://www.techstreet.com/products/1274288. [Last accessed: 14 Jul 2015]
  • Organisation for Economic Co-operation and Development (OECD). (2011). 201 SIAM 32, 19–21 April 2011. US/ICCA. SIDS Initial Assessment Profile, Chemical Category C1-13 Primary amines. Available from: http://webnet.oecd.org/Hpv/UI/handler.axd?id=9e86965a-715b-4cb8-99a4-f7113a364ea9 [Last accessed: 14 April 2015]
  • Organisation for Economic Co-operation and Development (OECD). (2013). CoCAM4, 16--18 April 2013. US/ICCA. SIDS Initial Assessment Profile, Aliphatic Secondary Amines. Available from: http://webnet.oecd.org/hpv/ui/handler.axd?id=D79CCEC2-4FF0-4DA5-88DE-9690EA9F3FF9 [Last accessed: 28 April 2015]
  • Osintseva, VP, Kulakov AE, Bonashevskaia TI, Kolbasova OV. (1966). Morphological studies on the effect of hexamethylene diamine on albino rats. Gig Sanit 31:89–91 (cited in Kennedy 2005)
  • Short RD, Johannsen FR, Scharden JL. (1991). A two-generation reproduction study in rats receiving diets containing hexamethylenediamine. Fundam Appl Toxicol 16:490–4
  • Texas Commission on Environmental Quality (TCEQ). (2012). TCEQ guidelines to develop toxicity factors (Revised RG-442). Texas Commission on Environmental Quality. Office of the Executive Director
  • Texas Commission on Environmental Quality (TCEQ). (2015). Development support document for hexamethylenediamine. CAS#124-09-4. Texas Commission on Environmental Quality, Toxicology Division, Office of the Executive Director. Available from: http://www.tceq.state.tx.us/toxicology/dsd/final.html. [Last accessed: 14 Jul 2015]
  • U.S. Environmental Protection Agency (USEPA). (1994). Methods for derivation of inhalation reference concentrations and application of inhalation dosimetry. EPA/600/8–90/066F. Washington, DC: U.S. Environmental Protection Agency, Office of Research and Development, Washington, DC
  • U.S. Environmental Protection Agency (USEPA). (2002). A review of the reference dose and reference concentration processes. EPA/630/P-02/002F. Washington, DC: U.S. Environmental Protection Agency, Risk Assessment Forum

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